TWiV 983: One flu vaccine for them all with Scott Hensley
Scott returns to TWiV to explain the development of an experimental mRNA vaccine that encodes hemagglutinin antigens against all known influenza A virus subtypes and influenza B virus lineages, and why he is worried about avian H5N1 influenza virus. Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker Guest: Scott Hensley Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Multivalent influenza mRNA vaccine (Science) •Influenza virus mRNA v...
Source: This Week in Virology - MP3 Edition - February 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 982: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the consistency of COVID-19 trial preprints with published reports and impact for decision making, the negative effect of preexisting immunity on Influenza vaccine responses transcends the impact of vaccine formulation type and vaccination history, highly pathogenic avian influenza A(H5N1) virus infection in farmed minks in Spain, Peru confirms H5N1 avian flu in marine mammals, prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies, bacillu...
Source: This Week in Virology - MP3 Edition - February 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 756: Precluding problematic polio prophylaxis
TWiV returns to the 2012 brouhaha over transmission experiments with avian H5N1 influenza virus, re-examines the claim of SARS-CoV-2 RNA integration into human DNA, and reviews the engineering and testing of a genetically stable version of the attenuated type 2 Sabin poliovirus vaccine. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV vaccine town halls 3:16 First smallpox vaccine day Revised masking and distancing (CDC) Science vs Spin (Sandman) Artifactual SARS-CoV-2 in...
Source: This Week in Virology - MP3 Edition - May 16, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 396: Influenza viruses with Peter Palese
Host: Vincent Racaniello Guest: Peter Palese Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines.   Become a patron of TWiV! Links for this episode Palese Laboratory Pig kidney neuraminidase (Hoppe Seylers Z Physiol Chem) DNAse in cytoplasmic DNA virus (Virology) Inhibitor of influenza virus neuraminidase (Virology) Influenza neuraminidase defective mutants (Virology) Swine influenza virus of 1976 RNA pattern (Nature) 1977 influenza H1N1 similar to 1950s strains (Nature) H5N1 influenza: Facts, not fear (PNAS) Influenza HA ...
Source: This Week in Virology - MP3 Edition - July 3, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 377: Chicken with a side of Zika
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVniks review the past week's findings on Zika virus and microcephaly, and reveal a chicken protein that provides insight on the restriction of transmission of avian influenza viruses to humans.   Links for this episode Larvicide not involved in microcephaly (CBS News) Obama seeks $1.8b for Zika virus (Guardian) Zika virus in Puerto Rico (MMWR) Zika virus in semen (EID) Zika virus in Indonesia (EID) Phylogeny of Zika virus (EID) Zika virus may cause mental disease (NYTimes) Zika virus from amniotic f...
Source: This Week in Virology - MP3 Edition - February 21, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 297: Ebola! Don't panic
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiVites present an all-ebolavirus episode, tackling virology, epidemiology, and approaches to prevention and cure that are in the pipeline. Links for this episode Risks and benefits of gain-of-function experiments (mBio) Scientists for Science US Policy for oversight of DURC (pdf) US framework for guiding H5N1 transmission expts (pdf) Extra oversight for H7N9 experiments (Science) TWiV 283: No Reston for the weary Is it Ebolavirus or Ebola virus? (virology blog) Ebola virus disease update&...
Source: This Week in Virology - MP3 Edition - August 10, 2014 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 227: Lacks security and bad poultry
Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, Alan Dove, and Kathy Spindler The complete TWiV team reviews the controversial publication of the HeLa cell genome, a missing vial of Guanarito virus in a BSL-4 facility, and human infections with avian influenza H7N9 virus. Links for this episode: Containment plan for poliovirus (pdf, WHO) Post-eradication of polio Ocular tropism of respiratory viruses (MMBR) Rally for medical research HeLa genome sequence withdrawn (ScienceInsider) Immortal life sequel (Rebecca Skloot) HeLa genome sequence publish...
Source: This Week in Virology - MP3 Edition - April 7, 2013 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 213: Not bad for a hobby
Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler In their final episode of the year, the TWiV team reviews twelve cool virology stories from 2012. Twelve virology stories from 2012: H5N1 (TWiV 190, 182, 177, 173, 168) Polymorphisms that control susceptibility (TWiV 175, 180) New virus receptors (TWiV 166, 210) XMRV: Last nail in the coffin (TWiV special) Polio eradication troubles in Pakistan (NY Times one, two, three; virology blog) Biomedical research crisis (TWiV 208, 184, 189, 194) Polydna...
Source: This Week in Virology - MP3 Edition - December 30, 2012 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 191: When two rights make a wrong
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Nissin Moussatche Nissin joins the TWiV crew to discuss an outbreak of lethal disease among Cambodian children, and recombination among attenuated herpesvirus vaccines leading to pathogenic viruses. Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Outbreak in Cambodia (CNN) Pathogen mix in Cambodian illness (ProMedMail) Undiagnosed illness in Cambodia (WHO) Enterovirus 71 (virol...
Source: This Week in Virology - MP3 Edition - July 15, 2012 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

JAMA: 2012-07-11, Vol. 308, No. 2, Author Interview
Interview with Björn Pasternak, MD, PhD, author of Risk of Adverse Fetal Outcomes Following Administration of a Pandemic Influenza A(H1N1) Vaccine During Pregnancy (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 10, 2012 Category: Journals (General) Authors: The JAMA Network Source Type: podcasts

Risk of Adverse Fetal Outcomes Following Administration of a Pandemic Influenza A(H1N1) Vaccine During Pregnancy
Interview with Björn Pasternak, MD, PhD, author of Risk of Adverse Fetal Outcomes Following Administration of a Pandemic Influenza A(H1N1) Vaccine During Pregnancy (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 10, 2012 Category: Journals (General) Authors: The JAMA Network Source Type: podcasts