Environmental risk factors for schizophrenia and bipolar disorder from childhood to diagnosis: a Swedish nested case-control study
CONCLUSIONS: There were both shared and unique environmental risk factors: SUDs and ACEs were risk factors for both disorders, while infections were more strongly associated with BD and urbanicity with SCZ.PMID:38425272 | DOI:10.1017/S0033291724000266 (Source: Psychological Medicine)
Source: Psychological Medicine - March 1, 2024 Category: Psychiatry Authors: Natassia Robinson Alexander Ploner Marica Leone Paul Lichtenstein Kenneth S Kendler Sarah E Bergen Source Type: research

Environmental risk factors for schizophrenia and bipolar disorder from childhood to diagnosis: a Swedish nested case-control study
CONCLUSIONS: There were both shared and unique environmental risk factors: SUDs and ACEs were risk factors for both disorders, while infections were more strongly associated with BD and urbanicity with SCZ.PMID:38425272 | DOI:10.1017/S0033291724000266 (Source: Psychological Medicine)
Source: Psychological Medicine - March 1, 2024 Category: Psychiatry Authors: Natassia Robinson Alexander Ploner Marica Leone Paul Lichtenstein Kenneth S Kendler Sarah E Bergen Source Type: research

Genetic causal association between varicella-zoster virus infection and psychiatric disorders: A 2-sample Mendelian randomization study
CONCLUSIONS: Our findings provide compelling evidence of a causal effect of chickenpox on the risk of BD. To gain a more comprehensive understanding of this association and its underlying mechanisms, additional research is needed. Such investigations are pivotal in identifying effective interventions for promoting BD prevention.PMID:38428645 | DOI:10.1016/j.bbr.2024.114927 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 1, 2024 Category: Neurology Authors: Bo Yan Pan Liao Conglin Wang Zhaoli Han Fangyuan Cheng Ping Lei Source Type: research

Genetic causal association between varicella-zoster virus infection and psychiatric disorders: A 2-sample Mendelian randomization study
CONCLUSIONS: Our findings provide compelling evidence of a causal effect of chickenpox on the risk of BD. To gain a more comprehensive understanding of this association and its underlying mechanisms, additional research is needed. Such investigations are pivotal in identifying effective interventions for promoting BD prevention.PMID:38428645 | DOI:10.1016/j.bbr.2024.114927 (Source: Brain Research)
Source: Brain Research - March 1, 2024 Category: Neurology Authors: Bo Yan Pan Liao Conglin Wang Zhaoli Han Fangyuan Cheng Ping Lei Source Type: research

Environmental risk factors for schizophrenia and bipolar disorder from childhood to diagnosis: a Swedish nested case-control study
CONCLUSIONS: There were both shared and unique environmental risk factors: SUDs and ACEs were risk factors for both disorders, while infections were more strongly associated with BD and urbanicity with SCZ.PMID:38425272 | DOI:10.1017/S0033291724000266 (Source: Psychological Medicine)
Source: Psychological Medicine - March 1, 2024 Category: Psychiatry Authors: Natassia Robinson Alexander Ploner Marica Leone Paul Lichtenstein Kenneth S Kendler Sarah E Bergen Source Type: research

GSE259219 Cas13bt3 knockdown of VEGFA mRNA in retinal organoid [scRNA-Seq]
Conclusions: AAV2.7m8 can be used for retina-wide transduction, and Cas13bt3 may be a potential new tool for control of VEGFA. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - March 1, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Causal effects of diabetic retinopathy on depression, anxiety and bipolar disorder in the European population: a Mendelian randomization study
ConclusionsThe results of the current MR analysis indicated a causal relationship between DR and BD in the European population, while there was no causal connection between DR and depression or anxiety. However, further research is needed to confirm these conclusions. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 1, 2024 Category: Endocrinology Source Type: research

Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1
Translational Psychiatry, Published online: 01 March 2024; doi:10.1038/s41398-024-02824-zDecreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1 (Source: Translational Psychiatry)
Source: Translational Psychiatry - March 1, 2024 Category: Psychiatry Authors: Luana Spano Cynthia Marie-Claire Oph élia Godin Apolline Lebras Cindie Courtin Jean-Louis Laplanche Marion Leboyer Bruno Aouizerate Antoine Lefrere Raoul Belzeaux Philippe Courtet Emilie Oli é Caroline Dubertret Raymund Schwan Val érie Aubin Paul Roux Source Type: research

Causal effects of diabetic retinopathy on depression, anxiety and bipolar disorder in the European population: a Mendelian randomization study
ConclusionsThe results of the current MR analysis indicated a causal relationship between DR and BD in the European population, while there was no causal connection between DR and depression or anxiety. However, further research is needed to confirm these conclusions. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 1, 2024 Category: Endocrinology Source Type: research

Early and Frequent Psychiatric Readmissions in a Brazilian Cohort of Hospitalized Patients Between 2001 and 2013
ConclusionEarly and frequent readmissions are linked to patients ’ demographics, clinical information and health system’s organization. Early readmission should be a priority in treatment planning to prevent frequent readmissions due to its strong association. (Source: Administration and Policy in Mental Health and Mental Health Services Research)
Source: Administration and Policy in Mental Health and Mental Health Services Research - March 1, 2024 Category: Psychiatry Source Type: research

Psychopathological symptoms in fibromyalgia and their associations with resistance to pharmacotherapy with SNRI
CONCLUSIONS: Modifiable psychopathological symptoms vary in FM T[+] vs. FM T[-] and are predictors of resistance to SNRI. Psychological assessment should be integrated into standard care for FM patients.PMID:38421347 | DOI:10.12740/PP/OnlineFirst/176000 (Source: Psychiatria Polska)
Source: Psychiatria Polska - February 29, 2024 Category: Psychiatry Authors: Anna Julia Krupa Adrian Andrzej Chrobak Zbigniew So łtys Mariusz Korkosz Jaroslaw Nowakowski Dominika Dudek Marcin Siwek Source Type: research

Co-treatment With Aripiprazole and Vincristine Sensitizes P-Glycoprotein-Overexpressing Drug-resistant MCF-7/ADR Breast Cancer Cells
CONCLUSION: Co-treatment with low doses of aripiprazole sensitized MCF-7/ADR cells to VIC. Combination therapy with aripiprazole may be a valuable tool for delaying or reducing cancer recurrence by targeting P-gp-overexpressing drug-resistant breast cancer cells.PMID:38423668 | DOI:10.21873/anticanres.16900 (Source: Cell Research)
Source: Cell Research - February 29, 2024 Category: Cytology Authors: Joo Kyung Shin Hyung Sik Kim Sungpil Yoon Source Type: research

Psychopathological symptoms in fibromyalgia and their associations with resistance to pharmacotherapy with SNRI
CONCLUSIONS: Modifiable psychopathological symptoms vary in FM T[+] vs. FM T[-] and are predictors of resistance to SNRI. Psychological assessment should be integrated into standard care for FM patients.PMID:38421347 | DOI:10.12740/PP/OnlineFirst/176000 (Source: Psychiatria Polska)
Source: Psychiatria Polska - February 29, 2024 Category: Psychiatry Authors: Anna Julia Krupa Adrian Andrzej Chrobak Zbigniew So łtys Mariusz Korkosz Jaroslaw Nowakowski Dominika Dudek Marcin Siwek Source Type: research