Understanding the diversity of cancer evolution based on computational simulation
(The Institute of Medical Science, The University of Tokyo) Understanding the principles of cancer evolution is important in designing a therapeutic strategy. A research group at The Institute of Medical Science, The University of Tokyo (IMSUT) announced a new simulation model that describes various modes of cancer evolution in a unified manner. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 30, 2020 Category: Biology Source Type: news

New evidence for optimizing malaria treatment in pregnant women
(The Institute of Medical Science, The University of Tokyo) The research, published in The Lancet Infectious Diseases is the fruit of joint project between investigators from around the world to conduct the largest individual patient data meta-analysis to date under The WorldWide Antimalarial Resistance Network (WWARN) umbrella. The study found that artemether-lumefantrine (AL) and other artemisinin-based combination therapies (ACTs) were significantly more effective than quinine, the current recommended treatment. Authors urgently call for further investigation into dose optimization for pregnant women to ensure the highe...
Source: EurekAlert! - Infectious and Emerging Diseases - April 29, 2020 Category: Infectious Diseases Source Type: news

Proteasome phase separation for destruction
(Tokyo Metropolitan Institute of Medical Science) Researchers at the Tokyo Metropolitan Institute of Medical Science (TMiMS) discovered proteasome-containing droplets, which are formed by acute hyperosmotic stress. The proteasome droplets also contain ubiquitin-tagged proteins and multiple interacting proteins, by which induce liquid-liquid phase separation of the proteasome for rapid degradation of unwanted proteins. The ubiquitin-dependent proteasome phase separation may be linked to clearance of aggregates that causes neurodegenerative diseases. These results were published in Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 27, 2020 Category: Cancer & Oncology Source Type: news

Free program on conducting scientific research without using laboratory animals
(Physicians Committee for Responsible Medicine) From June 22 to 25, students and early-career scientists will gather virtually for a free program of lectures, laboratory tours, interactive sessions, e-poster presentations, and virtual engagement with speakers and attendees on innovative methods to reduce and replace animal tests in toxicology and biomedical science. Originally planned to be hosted at Johns Hopkins University, the Summer School on Innovative Approaches in Science will now take place as a virtual meeting due to the COVID-19 pandemic. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 10, 2020 Category: Biology Source Type: news

Learning from Past Pandemics: Bridging the Science Gap
Source: Dart Center for Journalism and Trauma [Columbia University]. Published: 3/31/2020. This 46-minute webinar, part of Reporting and Covid-19: A Webinar Series for Journalists, discusses how journalists can best develop the right expert sources, and how they can effectively bridge complicated medical science and public understanding. (Video or Multimedia) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 31, 2020 Category: International Medicine & Public Health Source Type: news

Allegro: A little about Lucinda
  A little about me… After completing a BSc in Biomedical Science and Msc (Res) in Translational Oncology at the University of Sheffield, I took a gap year... The post Allegro: A little about Lucinda appeared first on Ashfield Healthcare. (Source: Ashfield Healthcare News)
Source: Ashfield Healthcare News - March 30, 2020 Category: Pharmaceuticals Authors: Ashfield Healthcare Communications Source Type: news

Nafamostat is expected to prevent the transmission of new coronavirus infection (COVID-19)
(The Institute of Medical Science, The University of Tokyo) Nafamostat mesylate (brand name: Fusan), which is the drug used to treat acute pancreatitis, may effectively block the requisite viral entry process the new coronavirus (SARS-CoV-2) uses to spread and cause disease (COVID-19). The University of Tokyo announced these new findings on March 18, 2020. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 30, 2020 Category: Biology Source Type: news

East Asian Lessons for Controlling Covid-19
By Nazihah Muhamad Noor and Jomo Kwame SundaramKUALA LUMPUR, Malaysia, Mar 26 2020 (IPS) By the third week of March 2020, the number of Covid-19 deaths in Italy had overtaken the number of deaths in China. Authorities all over the world are restricting the movements of their populations as part of efforts to control the spread of Covid-19. For the time being, more and more governments are benchmarking their responses on the very worst outbreaks in Wuhan and northern Italy. But lockdowns inevitably have adverse economic impacts, especially for businesses, particularly small ones heavily reliant on continuous turnover. Are ...
Source: IPS Inter Press Service - Health - March 26, 2020 Category: International Medicine & Public Health Authors: Nazihah Muhamad Noor and Jomo Kwame Sundaram Tags: Asia-Pacific Economy & Trade Featured Global Globalisation Headlines Health Human Rights Humanitarian Emergencies TerraViva United Nations Source Type: news

Finding the Achilles' heel of cancer cells
(Tokyo Metropolitan Institute of Medical Science) The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells. Researchers at the Tokyo Metropolitan Institute of Medical Science found that cancerous and non-cancerous cells depend on different factors for survival when their DNA replication is blocked. Drugs that inhibited the survival factor required by cancer cells would selectively make cancer cells more vulnerable to replication inhibition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 17, 2020 Category: International Medicine & Public Health Source Type: news

Elucidation of mechanisms that coordinate cell memory inheritance with DNA replication
(The Institute of Medical Science, The University of Tokyo) Why normal cells turn into cancer cells? One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation. The joint research groups of The Institute of Medical Science, the University of Tokyo, Yokohama City University, and Center for Integrated Protein Science Munich (CIPSM) have clarified new mechanism for controlling DNA methylation in cells. Ubiquitination of a protein called PAF15 is an important factor for the inheritance of DNA methylation, according to the new research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 16, 2020 Category: International Medicine & Public Health Source Type: news

The Vilcek Foundation allocates $150,000 for 2021 Vilcek Prizes for Creative Promise
(Vilcek Foundation) The Vilcek Foundation has allocated $150,000 to make 3 awards in 2021 to foreign-born researchers in biomedical science now living and working in the United States. These funds will support the award of the 2021 Vilcek Prizes for Creative Promise in Biomedical Science. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 10, 2020 Category: Biology Source Type: news

FDA Bans Shock Device Used On Patients At Judge Rotenberg Center In Canton
WASHINGTON (AP) — Federal officials on Wednesday banned electrical shock devices used to discourage aggressive, self-harming behavior in patients with mental disabilities. The announcement from the Food and Drug Administration follows years of pressure from disability rights groups and mental health experts who have called the treatment outdated, ineffective and unethical. The agency first announced its intent to ban the devices in 2016. For years, the shock devices have been used by only one place in the U.S., the Judge Rotenberg Educational Center of Canton, Massachusetts, a residential school for people with autism an...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 5, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Canton News FDA Judge Rotenberg Center Source Type: news

Pence’s role as US coronavirus overseer draws backlash
Critics point to record of scepticism of established medical science by vice-president (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - February 27, 2020 Category: Pharmaceuticals Source Type: news

Allegro: A little about Eleanor …
Joining the Allegro programme Originally from Derby, I completed my BSc in Biomedical Science in Manchester. Upon completion of my exams, I made the (somewhat clichéd) choice to... The post Allegro: A little about Eleanor… appeared first on Ashfield Healthcare. (Source: Ashfield Healthcare News)
Source: Ashfield Healthcare News - February 27, 2020 Category: Pharmaceuticals Authors: Ashfield Healthcare Communications Source Type: news

Iran confirms another dead because of the new coronavirus: official
Iran said on Sunday an Iranian infected by the new coronavirus died in the country, head of the Medical Science University in the Mazandaran province was quoted as saying, bringing the number of deaths to seven in the Islamic Republic. (Source: Reuters: Health)
Source: Reuters: Health - February 23, 2020 Category: Consumer Health News Tags: healthNews Source Type: news