CityU's CRISPR-assisted novel method detects RNA-binding proteins in living cells
(City University of Hong Kong) A research led by biomedical scientists from City University of Hong Kong (CityU) has developed a novel detection method, called CARPID, to identify binding proteins of specific RNAs in the living cells. It is expected the innovation can be applied in various cell researches, from identifying biomarkers of cancer diagnosis to detecting potential drug targets for treating viral diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 1, 2020 Category: International Medicine & Public Health Source Type: news

R & D of mRNA vaccine production technology against COVID-19 and further new coronavirus
(Innovation Center of NanoMedicine) The Innovation Center of NanoMedicine (iCONM) and the Tokyo Metropolitan Institute of Medical Science (TMIMS) started joint research with the aim of establishing a rapid vaccine development technology in preparation for the re-epidemic of covid-19 and the next coming pandemic of further new coronaviruses. An efficient procedure for the production of mRNA vaccine incorporated with immunostimulatory adjuvant functionality will be optimized using iCONM's smart nanomachine technologies and TMIMS's expertise for the discovery of recombinant vaccines. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 1, 2020 Category: International Medicine & Public Health Source Type: news

Novel pathology could improve diagnosis and treatment of Huntington ’ s and other diseases
Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington ’ s disease. (Source: University of Bristol news)
Source: University of Bristol news - June 30, 2020 Category: Universities & Medical Training Tags: Health, International, Postgraduate, Publications, Research; Faculty of Biomedical Sciences, School of Physiology, Pharmacology and Neuroscience, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Faculty of Biomedical Science Source Type: news

Blood cell mutations linked to leukemias are inevitable as we age
(RIKEN) A new study by researchers at the RIKEN Center for Integrative Medical Science in Japan reports differences in blood cell mutations between Japanese and European populations. The study found that these pre-clinical mutations were strongly associated with different types of cancers and can explain why Europeans have higher rates of chronic lymphocytic leukemia, while Japanese have higher rates of T-cell leukemia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 24, 2020 Category: Cancer & Oncology Source Type: news

The Lancet ’s editor: ‘The UK's response to coronavirus is the greatest science policy failure for a generation’                                                                           '
Richard Horton does not hold back in his criticism of the UK ’s response to the pandemic and the medical establishment’s part in backing fatal government decisionsCoronavirus – latest updatesSee all our coronavirus coverageThere is a school of thought that says now is not the time to criticise the government and its scientific advisers about the way they have handled theCovid-19 pandemic. Wait until all the facts are known and the crisis has subsided, goes this thinking, and then we can analyse the performance of those involved. It ’s safe to say thatRichard Horton, the editor of the influential medical journaltheL...
Source: Guardian Unlimited Science - June 14, 2020 Category: Science Authors: Andrew Anthony Tags: Health policy Science Coronavirus outbreak Microbiology Infectious diseases Medical research Chris Whitty Patrick Vallance Medicine UK news Society Politics Economics Public services policy Pharmaceuticals industry Source Type: news

How is electricity being used in wound care?
Some wounds just don't seem to heal. Now, pioneering medical research has come up with some promising new treatments that employ electricity to speed recovery, killing bacteria more effectively than traditional bandages or antibiotics. Here's a brief summary of these dramatic new developments in healthcare.  Medical research is providing revolutionary new wound care treatments that use electricity to speed healing. The problem: slow-healing or no-healing wounds Physicians and emergency room specialists have long been stymied by chronic wounds that resist most efforts to treat them using conventional antibio...
Source: Advanced Tissue - June 10, 2020 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound healing Wound Infection Source Type: news

Beyond the COVID-19 Pandemic: What Now?
WHO delivered medical supplies to fight the COVID-19 pandemic in the Republic of Congo in April 2020. Credit: World Health Organization (WHO)By Lawrence SurendraBANGKOK, Thailand, Jun 4 2020 (IPS) In the midst of the COVID 19 pandemic, the much-anticipated 73rd World Health Assembly (WHA) of the WHO concluded without any major controversies or disagreements. The landmark WHA resolution to bring the world together to fight the COVID-19 pandemic, co-sponsored by more than 130 countries, and adopted by consensus, called for the intensification of efforts to control the pandemic, and for equitable access to and fair distribut...
Source: IPS Inter Press Service - Health - June 4, 2020 Category: International Medicine & Public Health Authors: Lawrence Surendra Tags: Aid Climate Change Development & Aid Environment Featured Global Headlines Health Poverty & SDGs TerraViva United Nations Source Type: news

How the coronavirus could be prevented from invading a host cell
(University of California - Riverside) How might the novel coronavirus be prevented from entering a host cell in an effort to thwart infection? A team of biomedical scientists has made a discovery that points to a solution. The scientists, led by Maurizio Pellecchia in the UC Riverside School of Medicine, report in the journal Molecules that two proteases -- enzymes that break down proteins -- located on the surface of host cells and responsible for processing viral entry could be inhibited. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 29, 2020 Category: Infectious Diseases Source Type: news

Scientists at UC Riverside to study how lungs respond to worm infections
(University of California - Riverside) A biomedical scientist at the University of California, Riverside, has received a five-year, $3.3 million grant from the National Institutes of Health, or NIH, to investigate lung immune responses to parasitic worm infections. The research will explore how macrophages, a type of white blood cell, mediate tissue repair following infection-induced injury. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 21, 2020 Category: Infectious Diseases Source Type: news

Safer roads to school - Agrawal A, Bhoi S, Galw.ar S, Pal R, Deora H, Ghosh A, Moscote-Salazar LR.
Any and all advances made by medical science cannot solve the problem of road traffic injuries (RTIs) in school-going children, especially if the only concerned people are those of the medical fraternity. Children are a vulnerable part of the traveling pop... (Source: SafetyLit)
Source: SafetyLit - May 16, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

VE Day Marks the End of the Second World War-But the World is Still at War
UN Secretary-General Antonio Guterres calls on President Ashraf Ghani during a visit to Afghanistan’s capital Kabul to show solidarity with the Afghan people. Photo UNAMA / Fardin Waezi/June 2017By Siddharth ChatterjeeNAIROBI, Kenya, May 11 2020 (IPS) The world commemorated the 75th Anniversary to mark the end of the 2nd World War also called VE Day on 08 May 2020. With her nation, and much of the world still in lockdown due to COVID 19, England’s Queen marked 75 years since the allied victory in Europe with a poignant televised address. From Windsor Castle, Queen Elizabeth said, “the wartime generation knew that th...
Source: IPS Inter Press Service - Health - May 11, 2020 Category: International Medicine & Public Health Authors: Siddharth Chatterjee Tags: Armed Conflicts Crime & Justice Global Headlines Health Human Rights Humanitarian Emergencies Migration & Refugees Peace TerraViva United Nations Source Type: news

The Baltimore Bioterrorism Expert Who Inspired South Korea ’s COVID-19 Response
On Oct. 2, 2001, a 62-year-old photojournalist named Bob Stevens became the first victim of a coordinated series of anthrax attacks to be admitted to hospital. Stevens inhaled the deadly pathogen after opening one of several letters laced with anthrax spores which were mailed to the offices of prominent senators and media outlets across the U.S. Over the next seven weeks, he and four others would die as a result of their exposure. For a shell-shocked nation still reeling from the single deadliest terrorist attack in human history on September 11, it was a disturbing realization that there was a new wave of challenges to Am...
Source: TIME: Health - May 6, 2020 Category: Consumer Health News Authors: David Cox Tags: Uncategorized COVID-19 Source Type: news

Understanding the diversity of cancer evolution based on computational simulation
(The Institute of Medical Science, The University of Tokyo) Understanding the principles of cancer evolution is important in designing a therapeutic strategy. A research group at The Institute of Medical Science, The University of Tokyo (IMSUT) announced a new simulation model that describes various modes of cancer evolution in a unified manner. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 30, 2020 Category: Biology Source Type: news

New evidence for optimizing malaria treatment in pregnant women
(The Institute of Medical Science, The University of Tokyo) The research, published in The Lancet Infectious Diseases is the fruit of joint project between investigators from around the world to conduct the largest individual patient data meta-analysis to date under The WorldWide Antimalarial Resistance Network (WWARN) umbrella. The study found that artemether-lumefantrine (AL) and other artemisinin-based combination therapies (ACTs) were significantly more effective than quinine, the current recommended treatment. Authors urgently call for further investigation into dose optimization for pregnant women to ensure the highe...
Source: EurekAlert! - Infectious and Emerging Diseases - April 29, 2020 Category: Infectious Diseases Source Type: news

Proteasome phase separation for destruction
(Tokyo Metropolitan Institute of Medical Science) Researchers at the Tokyo Metropolitan Institute of Medical Science (TMiMS) discovered proteasome-containing droplets, which are formed by acute hyperosmotic stress. The proteasome droplets also contain ubiquitin-tagged proteins and multiple interacting proteins, by which induce liquid-liquid phase separation of the proteasome for rapid degradation of unwanted proteins. The ubiquitin-dependent proteasome phase separation may be linked to clearance of aggregates that causes neurodegenerative diseases. These results were published in Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 27, 2020 Category: Cancer & Oncology Source Type: news