Association between Antibiotic Consumption and Incidence of Clostridioides difficile Infection in a Hospital. Journal of Korean medical science 35(47): e407
Previous exposure to antimicrobials is a major risk factor for Clostridioides difficile infection (CDI). Antibiotic prescription and C. difficile toxin assay records of patients admitted to a tertiary hospital in Korea from 2009 to 2013 were collected to investigate the association between antibiotic consumption and CDI incidence. A Spearman ' s correlation analysis between CDI incidence (positive result of toxin assay/10,000 admissions) and antibiotic consumption (defined daily dose/1,000 patient-days) was performed on a monthly basis. Using the matched month approach, we found a significant correlation between CDI rate a...
Source: Current Awareness Service for Health (CASH) - January 15, 2021 Category: Consumer Health News Source Type: news

Broadening participation in clinical trials: A win for all
The objective is to engage in rea l-world, evidence-based research and bring trials to the local community, where a significant proportion of cancer care is rendered,” he adds.   To help, Cardinal Health ’s real-world evidence and insights teams analyze the real-world data collected from the sites, which can be compared to results from clinical trials to demonstrate the real-world value of therapies.   By bringing these studies to the community, many of the usual challenges are overcome, adds Gajra. These include trial site location (typically academic institutions) and the distances that must be traveled to reac...
Source: EyeForPharma - January 6, 2021 Category: Pharmaceuticals Authors: Joseph Constance Source Type: news

Discovery of aging mechanism for hematopoietic stem cells
(The Institute of Medical Science, The University of Tokyo) By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 24, 2020 Category: International Medicine & Public Health Source Type: news

Women ’ s Bodies, COVID-19 and Male Chauvinism
By Jan LundiusSTOCKHOLM / ROME, Dec 11 2020 (IPS) COVID-19 has in some nations been converted into a noxious, political issue. One of many worrying examples is the rhetoric of Brazil´s president. On 10 November, when Brazil´s COVID-19 death toll surpassed 162,000 victims – the numbers have continued to raise and are now 179,032 second only to USA´s 296,745 – Jair Bolsonaro minimized the effects of COVID-19 by stating: ”All of us are going to die one day. There is no point in escaping from that, in escaping from reality. We have to cease being a country of sissies.” Bolsonaro actually said maricas, which like sis...
Source: IPS Inter Press Service - Health - December 11, 2020 Category: International Medicine & Public Health Authors: Jan Lundius Tags: Education Gender Gender Identity Global Headlines Health Human Rights Humanitarian Emergencies Labour LGBTQ TerraViva United Nations Source Type: news

Development of a new method for decoding viral genes
(The Institute of Medical Science, The University of Tokyo) A research team led by Professor Yasushi Kawaguchi of the Institute of Medical Science, the University of Tokyo, developed a new decoding method for viral genes that can easily and quickly obtain even non-canonical genetic information. Using this new decoding method, they identified nine novel proteins encoded by herpes simplex virus type 1(HSV-1) and found that one of them, piUL49, is a pathogenic factor that specifically controls the onset of herpes encephalitis . (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 7, 2020 Category: International Medicine & Public Health Source Type: news

The New Coronavirus Vaccine Is Changing The Future Of Medicine
The success of mRNA vaccines could usher in a new era of medical science — not just for vaccines, but for cancer treatments, gene therapy, and more. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 2, 2020 Category: Pharmaceuticals Authors: Caroline Seydel, Contributor Tags: Healthcare /healthcare Innovation /innovation Editors' Pick editors-pick Coronavirus Source Type: news

Stanford faculty blasts Hoover senior fellow and presidential adviser Scott Atlas
Dr. Scott Atlas is known to the nation as a controversial Covid-19 advisor to President Donald Trump. But he's also part of the Stanford University community, and faculty there are not happy with him. On Thursday, the Stanford Faculty Senate took up a resolution condemning Atlas and voted overwhelmingly in favor of it — 85% of the faculty joined in to blast his actions to "promote a view of Covid-19 that contradicts medical science." But the Senate did not ask leadership at the Palo Alto uni versity… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 20, 2020 Category: Biotechnology Authors: J. Jennings Moss Source Type: news

Jet-printing microfluidic devices on demand
– a new paper from engineering and biomedical scientists at the University of Oxford and spin-out company iotaSciences Ltd– describes a... (Source: The Scientist)
Source: The Scientist - November 12, 2020 Category: Science Tags: The Scientist The Marketplace Source Type: news

Sixty-year old cohort study reveals adolescent value predicts wellbeing in older age
(Tokyo Metropolitan Institute of Medical Science) Subjective wellbeing leads to better health, but we did not know what in our younger years determines our wellbeing in old age. Researchers at the Tokyo Metropolitan Institute of Medical Science have demonstrated that adolescents who valued their interests and curiosity had higher wellbeing in old age from a 60-year-old cohort in the UK. We additionally found that adolescents with low self-control who valued money and steady jobs had significantly lower wellbeing in old age. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 11, 2020 Category: International Medicine & Public Health Source Type: news

FDA Issues Recommendations for Certain High-Risk Groups Regarding Mercury-Containing Dental Amalgam
 For Immediate Release:September 24, 2020Statement From:Director - CDRH Offices: Office of the Center DirectorDr. Jeffrey E. Shuren MD, JDPart of our role in protecting patients is to regularly evaluate, monitor and update scientific evidence on the risks from medical devices —including issues related to the materials used in devices, such as metals. In the case of implanted and inserted medical devices, where materials may be in contact with the body for extended periods of time, we evaluate safety issues involved with, among other things, the body’s long-term expos ure to certain materials, taking into account t...
Source: Dental Technology Blog - November 11, 2020 Category: Dentistry Source Type: news

The Covid Pandemic: Broadening the Discourse
Thailand’s COVID-19 response an example of resilience and solidarity: a UN Resident Coordinator’s BlogBy Asoka BandarageCOLOMBO, Sri Lanka, Nov 10 2020 (IPS) SARS-CoV-2, the corona virus that causes COVID-19, has been spreading exponentially across the world over the last ten or so months. As of November 6th, according to the Center for Systems Science at Johns Hopkins University, there have been 49,195,581 cases of COVID-19, including 1,241,031 deaths. More than a third of the global population has been placed on lockdown. The global economy is experiencing the deepest global recession since World War 2 and massive n...
Source: IPS Inter Press Service - Health - November 10, 2020 Category: International Medicine & Public Health Authors: Asoka Bandarage Tags: Featured Global Headlines Health Human Rights Humanitarian Emergencies Peace TerraViva United Nations Source Type: news

The sole function of the clitoris is female orgasm. Is that why it ’s ignored by medical science?
Medical textbooks are full of anatomical pictures of the penis, but the clitoris barely rates a mention. Many medical professionals are uncomfortable even talking about itProfessor Caroline de Costa is awaiting feedback. Several months ago the editor of the Australian and New Zealand Journal of Obstetrics and Gynaecology requested an editorial from a world-renowned Melbourne urologist to address what she saw as a lack of research and, more concerningly, a persistent lack of knowledge about an essential part of the female reproductive system.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 31, 2020 Category: Science Authors: Calla Wahlquist Tags: Women Australia news Health Science Sex Sexuality Medical research Melbourne Adelaide Source Type: news

City, University of London academics develop algorithm to analyse HeLa cancer cells
(City University London) Dr Constantino Carlos Reyes-Aldasoro and Dr Cefa Karabag collaborate with the Francis Crick Institute on a novel approach published in thePLoS ONE journal, which significantly reduces the amount of time taken to analyse the cell line named after Henrietta Lacks, an African-American woman whose contribution to medical science was only formally acknowledged decades after her death. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 26, 2020 Category: Cancer & Oncology Source Type: news

Chief Professions Officers ’ medicines mechanisms programme
NHS England and NHS Improvement would like to hear your thoughts on proposals for greater flexibility to be given to how dental hygienists, dental therapists, biomedical scientists, clinical scientists, operating department practitioners, podiatrist independent prescribers, physiotherapist independent prescribers, and paramedics are able to access medicines for their patients. (Source: NHS Networks)
Source: NHS Networks - October 21, 2020 Category: UK Health Source Type: news

A new strategy for siRNA stabilization by an artificial cationic oligosaccharide
(Tokyo Metropolitan Institute of Medical Science) Instability of small interfering RNA (siRNA) is one of the obstacles in the development of siRNA-based drugs. Researchers at Tokyo Metropolitan Institute of Medical Science and Tokyo University of Science have developed a new strategy for improvement of siRNA stability by using an artificial cationic oligosaccharide combined with phosphorothioate linkages. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 16, 2020 Category: Biology Source Type: news