Antifibrotic effect of silymarin on arecoline-induced fibrosis in primary human buccal fibroblasts: an in silico and in vitro analysis
CONCLUSION: Silymarin effectively inhibited fibroblast proliferation and downregulated genes associated with cancer progression and EMT pathway, both of which are implicated in malignant transformation. To our knowledge, this study represents the first exploration of silymarin's potential as a novel therapeutic agent in an in vitro model of OSMF.PMID:38356030 | DOI:10.1007/s11033-023-09177-8 (Source: Mol Biol Cell)
Source: Mol Biol Cell - February 15, 2024 Category: Molecular Biology Authors: Divyambika Catakapatri Venugopal Paramesh Viswanathan Soundharya Ravindran Alan Mathew Punnoose Madhavan Yasasve Davis G Dicky John Lavanya Prabhakar Gnanasambandan Ramanathan Sathasivasubramanian Sankarapandian Vijayalakshmi Ramshankar Source Type: research
Antifibrotic effect of silymarin on arecoline-induced fibrosis in primary human buccal fibroblasts: an in silico and in vitro analysis
CONCLUSION: Silymarin effectively inhibited fibroblast proliferation and downregulated genes associated with cancer progression and EMT pathway, both of which are implicated in malignant transformation. To our knowledge, this study represents the first exploration of silymarin's potential as a novel therapeutic agent in an in vitro model of OSMF.PMID:38356030 | DOI:10.1007/s11033-023-09177-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - February 15, 2024 Category: Molecular Biology Authors: Divyambika Catakapatri Venugopal Paramesh Viswanathan Soundharya Ravindran Alan Mathew Punnoose Madhavan Yasasve Davis G Dicky John Lavanya Prabhakar Gnanasambandan Ramanathan Sathasivasubramanian Sankarapandian Vijayalakshmi Ramshankar Source Type: research
Antifibrotic effect of silymarin on arecoline-induced fibrosis in primary human buccal fibroblasts: an in silico and in vitro analysis
CONCLUSION: Silymarin effectively inhibited fibroblast proliferation and downregulated genes associated with cancer progression and EMT pathway, both of which are implicated in malignant transformation. To our knowledge, this study represents the first exploration of silymarin's potential as a novel therapeutic agent in an in vitro model of OSMF.PMID:38356030 | DOI:10.1007/s11033-023-09177-8 (Source: Mol Biol Cell)
Source: Mol Biol Cell - February 15, 2024 Category: Molecular Biology Authors: Divyambika Catakapatri Venugopal Paramesh Viswanathan Soundharya Ravindran Alan Mathew Punnoose Madhavan Yasasve Davis G Dicky John Lavanya Prabhakar Gnanasambandan Ramanathan Sathasivasubramanian Sankarapandian Vijayalakshmi Ramshankar Source Type: research
Antifibrotic effect of silymarin on arecoline-induced fibrosis in primary human buccal fibroblasts: an in silico and in vitro analysis
CONCLUSION: Silymarin effectively inhibited fibroblast proliferation and downregulated genes associated with cancer progression and EMT pathway, both of which are implicated in malignant transformation. To our knowledge, this study represents the first exploration of silymarin's potential as a novel therapeutic agent in an in vitro model of OSMF.PMID:38356030 | DOI:10.1007/s11033-023-09177-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - February 15, 2024 Category: Molecular Biology Authors: Divyambika Catakapatri Venugopal Paramesh Viswanathan Soundharya Ravindran Alan Mathew Punnoose Madhavan Yasasve Davis G Dicky John Lavanya Prabhakar Gnanasambandan Ramanathan Sathasivasubramanian Sankarapandian Vijayalakshmi Ramshankar Source Type: research
Quercetin Ameliorates Cognitive Impairment in Depression by Targeting HSP90 to Inhibit NLRP3 Inflammasome Activation
AbstractCognitive dysfunction was a common symptom of major depressive disorder (MDD). In previous studies, psychological stress leads to activation and proliferation of microglial cells in different brain regions. Quercetin, a bioflavonoid derived from vegetables and fruits, exerts anti-inflammatory effects in various diseases. To demonstrate the role of quercetin in the hippocampal inflammatory response in depress mice. The chronic unpredictable stress (CUS) depressive mice model built is used to explore the protective effects of quercetin on depression. Neurobehavioral test, protein expression of NOD-like receptor the...
Source: Molecular Neurobiology - February 8, 2024 Category: Neurology Source Type: research
Economic and Productive Comparison of Rutin and Rutin-Loaded Chitosan Alginate Nanoparticles Against Lead-Induced Oxidative Stress in Cobb and Arbor Broiler Breeds
In conclusion, RCA NPs supplementation could be a promising nanoformulation in poultry production through enhancing the antioxidant capacity and bioavailability of rutin.PMID:38153670 | DOI:10.1007/s12011-023-04019-x (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - December 28, 2023 Category: Biology Authors: Noha M Wahed Mohamed Abomosallam Basma M Hendam Zeinab Shouman Nada Ma Hashem Shimaa A Sakr Source Type: research
Economic and Productive Comparison of Rutin and Rutin-Loaded Chitosan Alginate Nanoparticles Against Lead-Induced Oxidative Stress in Cobb and Arbor Broiler Breeds
In conclusion, RCA NPs supplementation could be a promising nanoformulation in poultry production through enhancing the antioxidant capacity and bioavailability of rutin.PMID:38153670 | DOI:10.1007/s12011-023-04019-x (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - December 28, 2023 Category: Biology Authors: Noha M Wahed Mohamed Abomosallam Basma M Hendam Zeinab Shouman Nada Ma Hashem Shimaa A Sakr Source Type: research
Economic and Productive Comparison of Rutin and Rutin-Loaded Chitosan Alginate Nanoparticles Against Lead-Induced Oxidative Stress in Cobb and Arbor Broiler Breeds
In conclusion, RCA NPs supplementation could be a promising nanoformulation in poultry production through enhancing the antioxidant capacity and bioavailability of rutin.PMID:38153670 | DOI:10.1007/s12011-023-04019-x (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - December 28, 2023 Category: Biology Authors: Noha M Wahed Mohamed Abomosallam Basma M Hendam Zeinab Shouman Nada Ma Hashem Shimaa A Sakr Source Type: research
Economic and Productive Comparison of Rutin and Rutin-Loaded Chitosan Alginate Nanoparticles Against Lead-Induced Oxidative Stress in Cobb and Arbor Broiler Breeds
In conclusion, RCA NPs supplementation could be a promising nanoformulation in poultry production through enhancing the antioxidant capacity and bioavailability of rutin.PMID:38153670 | DOI:10.1007/s12011-023-04019-x (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - December 28, 2023 Category: Biology Authors: Noha M Wahed Mohamed Abomosallam Basma M Hendam Zeinab Shouman Nada Ma Hashem Shimaa A Sakr Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats
CONCLUSIONS: A notable pharmacokinetic drug interaction between QUE and AMD was observed in rats and warrants possible drug interaction study in humans, suggesting AMD dose adjustment specifically in patients with arrhythmia having a pre-treatment history and simultaneous administration of QUE-containing products.PMID:38095371 | DOI:10.26355/eurrev_202312_34561 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: E Ahmad M Jahangir N I Bukhari J Khan A Sarwar T Aziz G Nabi M Alharbi H A Thamer A F Alasmari Source Type: research
