Potential glioblastoma treatment has roots in UCLA graduate research
A potential new treatment for glioblastoma that recently received approval for clinical trials not only was developed by three UCLA faculty members but also traces its roots back to 2005, when one of the researchers was a UCLA graduate student.The oral medication, a small molecule called ERAS-801, targets a rogue gene found in approximately 60% of people with the aggressive form of brain cancer. Developed by UCLA professors David Nathanson, Michael Jung and Dr. Timothy Cloughesy, the drug would provide a  complement to existing treatments — surgery, radiation and chemotherapy.In December, ERAS-801 received a go-ahead fr...
Source: UCLA Newsroom: Health Sciences - March 15, 2022 Category: Universities & Medical Training Source Type: news

Women-led life sciences companies push the boundaries of scientific capabilities
The companies are leaders in their field responsible for breakthrough achievements that have pushed the boundaries of scientific capabilities. While these companies may be saving lives and broadening our understanding of health, it may be hard for the general public to cut through the jargon to understand how these firms are revolutionizing the life sciences sector. If you’re like us and want to know more about these companies and th eir work (but you’re also like us and don’t have a biochemistry… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 15, 2022 Category: Pharmaceuticals Authors: Ari Mahrer Source Type: news

Inside the High-Stakes Race to Test the Covid Tests
Researchers in Atlanta have helped the federal government evaluate dozens of Covid tests and pioneer a new model for developing novel diagnostics. (Source: NYT Health)
Source: NYT Health - March 15, 2022 Category: Consumer Health News Authors: Emily Anthes Tags: your-feed-science your-feed-health Tests (Medical) Product Tests Coronavirus (2019-nCoV) Antibodies Biology and Biochemistry Biotechnology and Bioengineering Influenza Source Type: news

Superior Covid protection from better face masks, research shows
New research from the universities of Surrey and Bristol and ESPCI Paris has shown that FFP2 (filtering facepiece) respirator masks are five times more efficient at filtering particles which carry the Covid-19 virus than cloth masks. (Source: University of Bristol news)
Source: University of Bristol news - March 3, 2022 Category: Universities & Medical Training Tags: Health, Research; Faculty of Science, Faculty of Science, School of Chemistry, Faculty of Life Sciences, Faculty of Life Sciences, School of Biochemistry; Press Release Source Type: news

John Q. Trojanowski Dies at 75; Changed Understanding of Brain Diseases
He was able to combine pathology and biochemistry to help figure out how and why people get diseases as disparate as Alzheimer ’s, Parkinson’s and A.L.S. (Source: NYT Health)
Source: NYT Health - March 1, 2022 Category: Consumer Health News Authors: Gina Kolata Tags: Deaths (Obituaries) Alzheimer ' s Disease Parkinson Amyotrophic Lateral Sclerosis University of Pennsylvania Research Proteins Trojanowski, John Q Lee, Virginia M-Y Tau proteins Source Type: news

New research shows virus plays ultimate game of ‘ hide and seek ’ with immune system
SARS-CoV-2-infected individuals could have different variants hidden in different parts of the body. (Source: University of Bristol news)
Source: University of Bristol news - March 1, 2022 Category: Universities & Medical Training Tags: Business and Enterprise, Grants and Awards, Health, International, Research; Faculty of Life Sciences, Faculty of Life Sciences, School of Biochemistry; Press Release Source Type: news

Geisel Professors Dunlap and Loros Receive Pioneer Awards from Society for Research on Biological Rhythms
Jennifer Loros, PhD, a professor of Biochemistry and Cell Biology and of Molecular Systems Biology, and Jay Dunlap, PhD, the Nathan Smith Professor of Molecular and Systems Biology and of Biochemistry and Cell Biology, at Dartmouth’s Geisel School of Medicine have both received the Pioneer Program Award from the Society for Research on Biological Rhythms. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - February 17, 2022 Category: Hospital Management Authors: Timothy Dean Tags: News Jay Dunlap Jennifer Loros Source Type: news

She Wasn ’t on PCP, but Her Own Body Made Her Hallucinate
In “A Molecule Away From Madness,” Sara Manning Peskin explains how neurological aberrations can kill. (Source: NYT Health)
Source: NYT Health - February 10, 2022 Category: Consumer Health News Authors: Annie Murphy Paul Tags: Books and Literature Brain A Molecule Away From Madness: Tales of the Hijacked Brain (Book) Biology and Biochemistry Mental Health and Disorders Peskin, Sara Manning Source Type: news

Sweating the small stuff: Smartwatch developed at UCLA measures key stress hormone
The human body responds to stress, from the everyday to the extreme, by producing a hormone called cortisol.To date, it has been impractical to measure cortisol as a way to potentially identify conditions such as depression and post-traumatic stress, in which levels of the hormone are elevated. Cortisol levels traditionally have been evaluated through blood samples by professional labs, and while those measurements can be useful for diagnosing certain diseases, they fail to capture changes in cortisol levels over time.Now, a UCLA research team has developed a device that could be a major step forward: a smartwatch that ass...
Source: UCLA Newsroom: Health Sciences - February 7, 2022 Category: Universities & Medical Training Source Type: news

The Future is Carbon Farming, Not Cattle Ranching, says Impossible Foods CEO
A new study published Feb. 1 in the journal PLOS Climate suggests that phasing out animal agriculture over the next 15 years would have the same effect as a 68% reduction in carbon dioxide emissions through the end of the century. The analysis draws upon data from the Intergovernmental Panel on Climate Change (IPCC) and the United Nations Food and Agriculture Organization (FAO) showing that at least a third of anthropogenic methane emissions and more than 90% of nitrous oxide emissions—both powerful planet-warming emissions—come from livestock. It combines those findings with estimates of the amount of biomass...
Source: TIME: Science - February 3, 2022 Category: Science Authors: Aryn Baker Tags: Uncategorized climate change Climate Is Everything embargoed study Food & Agriculture healthscienceclimate Londontime overnight Source Type: news

First patients of pioneering CAR T-cell therapy ‘cured of cancer’
Cancer-killing cells still present 10 years on, with results suggesting therapy is a cure for certain blood cancersTwo of the first human patients to be treated with a revolutionary therapy that engineers immune cells to target specific types of cancer still possess cancer-killing cells a decade later with no sign of their illness returning.The finding suggests CAR T-cell therapy constitutes a “cure” for certain blood cancers, although adapting it to treat solid tumours is proving more challenging.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 2, 2022 Category: Science Authors: Linda Geddes Science correspondent Tags: Cancer Medical research Society Science Health Immunology Biochemistry and molecular biology Source Type: news

U.S. FDA Approves CABENUVA (rilpivirine and cabotegravir) for Use Every Two Months, Expanding the Label of the First and Only Long-Acting HIV Treatment
TITUSVILLE, N.J., February 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the U.S. Food and Drug Administration (FDA) has approved an expanded label for CABENUVA (rilpivirine and cabotegravir) to be administered every two months for the treatment of HIV-1 in virologically suppressed adults (HIV-1 RNA less than 50 copies per milliliter [c/ml]) on a stable regimen, with no history of treatment failure, and with no known or suspected resistance to either rilpivirine or cabotegravir. The novel regimen was co-developed as part of a collaboration with ViiV Healthcare and builds on Janss...
Source: Johnson and Johnson - February 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

£ 4.9 million award to investigate pioneering biological electronics
Researchers from universities across the UK, led by the University of Bristol, have been awarded £ 4.9 million from the Biotechnology and Biological Sciences Research Council (BBSRC), the UK ’ s largest bioscience funder, to investigate how electrons and energy flow through biological molecules by building artificial protein-based wires and circuits. (Source: University of Bristol news)
Source: University of Bristol news - January 28, 2022 Category: Universities & Medical Training Tags: Announcements, Grants and Awards, Research; Faculty of Life Sciences, Faculty of Life Sciences, School of Biochemistry, Faculty of Science, Faculty of Science, School of Chemistry; Press Release Source Type: news

How antivirals provide hope to vulnerable Covid patients
Pfizer says its recently approved Paxlovid drug has almost 90% success in preventing severe illness if taken soon after infectionThe recent decision by regulators to approve the antiviral agent Paxlovid for use in the UK adds a formidable new weapon to the arsenal of treatments for Covid-19. Pfizer says the drug has almost 90% success in preventing severe illness in vulnerable adults if taken soon after infection occurs. Paxlovid is one of a growing repertoire of antiviral medicines – which also includes Merck’s agent Molnurpiravir – that can be given to people who have contracted the disease. Crucially, antivirals ...
Source: Guardian Unlimited Science - January 16, 2022 Category: Science Authors: Robin McKie Tags: Coronavirus Infectious diseases Medical research Microbiology Science World news Pfizer Pharmaceuticals industry Immunology Biochemistry and molecular biology Source Type: news