Comparative analysis of proteomic adaptations in Enterococcus faecalis and Enterococcus faecium after long term bile acid exposure
In this study, we investigated by data-independent acquisi... (Source: BMC Microbiology)
Source: BMC Microbiology - April 3, 2024 Category: Microbiology Authors: Annika Dreyer, Christof Lenz, Uwe Gro ß, Wolfgang Bohne and Andreas Erich Zautner Tags: Research Source Type: research
Aldicarb disturbed bile acid, steroid hormone and oxylipin homeostasis in C57BL/6 J mice
Ecotoxicol Environ Saf. 2024 Apr 1;275:116285. doi: 10.1016/j.ecoenv.2024.116285. Online ahead of print.ABSTRACTMounting evidence has shown that the gut microbiota plays a key role in human health. The homeostasis of the gut microbiota could be affected by many factors, including environmental chemicals. Aldicarb is a carbamate insecticide used to control a variety of insects and nematode pests in agriculture. Aldicarb is highly toxic and its wide existence has become a global public health concern. In our previous study, we have demonstrated that aldicarb disturbed the gut microbial community structure and composition. Ho...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xin Liu Pengcheng Tu Ying Zhang Weichen Xu Jinjun Shan Bei Gao Source Type: research
Bile salt hydrolase activity-based probes for monitoring gut microbial bile acid metabolism
Chembiochem. 2024 Apr 2:e202300821. doi: 10.1002/cbic.202300821. Online ahead of print.ABSTRACTBile acids are bioactive metabolites that are biotransformed into secondary bile acids by the gut microbiota, a vast consortium of microbes that inhabit the intestines. The first step in intestinal secondary bile acid metabolism is carried out by a critical enzyme, bile salt hydrolase (BSH), that catalyzes the gateway reaction that precedes all subsequent microbial metabolism of these important metabolites. As gut microbial metabolic activity is difficult to probe due to the complex nature of the gut microbiome, approaches are ne...
Source: Chembiochem - April 2, 2024 Category: Biochemistry Authors: Lin Han Raymond Xu Amanda Conwell Sola Takahashi Bibudha Parasar Pamela Chang Source Type: research
Dietary emulsifier polysorbate 80 exposure accelerates age-related cognitive decline
This study provides strong evidence that dietary-induced gut microbiota dysbiosis may be a risk factor for age-related cognitive decline.PMID:38565398 | DOI:10.1016/j.bbi.2024.03.052 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - April 2, 2024 Category: Neurology Authors: Lan Zhang Zhenyu Yin Xilei Liu Ge Jin Yan Wang Linlin He Meimei Li Xiaoqi Pang Bo Yan Zexi Jia Jiahui Ma Jingge Wei Fangyuan Cheng Dai Li Lu Wang Zhaoli Han Qiang Liu Fanglian Chen Hailong Cao Ping Lei Source Type: research
Robotic Biliary Resection for Type I Choledochal Cyst With Dual Hepaticojejunostomy
Am Surg. 2024 Apr 2:31348241241681. doi: 10.1177/00031348241241681. Online ahead of print.ABSTRACTThe distal bile duct was isolated and transected with a frozen section examination confirming the absence of malignancy. Attention was then shifted to constructing a 60 cm Roux limb by first identifying and transecting the proximal jejunum 40 cm from the ligamentum of Treitz. A side-to-side stapled jejunojejunostomy anastomosis was completed. The Roux limb was transposed toward the porta hepatis through an antecolic approach.PMID:38565320 | DOI:10.1177/00031348241241681 (Source: The American Surgeon)
Source: The American Surgeon - April 2, 2024 Category: Surgery Authors: Maria Christodoulou Tara Pattilachan Sharona Ross George Peek Iswanto Sucandy Source Type: research
What Happens After Discharge? A 2+ Year Follow-Up After Laparoscopic Subtotal Fenestrating and Reconstituting Cholecystectomy
Am Surg. 2024 Apr 2:31348241241617. doi: 10.1177/00031348241241617. Online ahead of print.ABSTRACTLaparoscopic subtotal cholecystectomy (LSC) is utilized to prevent complications in the difficult cholecystectomy. Medium-term outcomes are poorly studied for fenestrating and reconstituting operative techniques. A single-institution retrospective review was undertaken of all LSCs. A telephone survey was used to identify complications addressed at other institutions. We performed subgroup analyses by operative approach and of patients requiring postoperative endoscopic intervention (ERC). 28 patients met inclusion criteria. Th...
Source: The American Surgeon - April 2, 2024 Category: Surgery Authors: Sunjay S Kumar Erin Briggs Sami Tannouri Talar Tatarian Michael J Pucci Renee M Tholey Karen A Chojnacki Courtney Foley Francesco Palazzo Source Type: research
Aldicarb disturbed bile acid, steroid hormone and oxylipin homeostasis in C57BL/6 J mice
Ecotoxicol Environ Saf. 2024 Apr 1;275:116285. doi: 10.1016/j.ecoenv.2024.116285. Online ahead of print.ABSTRACTMounting evidence has shown that the gut microbiota plays a key role in human health. The homeostasis of the gut microbiota could be affected by many factors, including environmental chemicals. Aldicarb is a carbamate insecticide used to control a variety of insects and nematode pests in agriculture. Aldicarb is highly toxic and its wide existence has become a global public health concern. In our previous study, we have demonstrated that aldicarb disturbed the gut microbial community structure and composition. Ho...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xin Liu Pengcheng Tu Ying Zhang Weichen Xu Jinjun Shan Bei Gao Source Type: research
Bile salt hydrolase activity-based probes for monitoring gut microbial bile acid metabolism
Chembiochem. 2024 Apr 2:e202300821. doi: 10.1002/cbic.202300821. Online ahead of print.ABSTRACTBile acids are bioactive metabolites that are biotransformed into secondary bile acids by the gut microbiota, a vast consortium of microbes that inhabit the intestines. The first step in intestinal secondary bile acid metabolism is carried out by a critical enzyme, bile salt hydrolase (BSH), that catalyzes the gateway reaction that precedes all subsequent microbial metabolism of these important metabolites. As gut microbial metabolic activity is difficult to probe due to the complex nature of the gut microbiome, approaches are ne...
Source: Chembiochem - April 2, 2024 Category: Biochemistry Authors: Lin Han Raymond Xu Amanda Conwell Sola Takahashi Bibudha Parasar Pamela Chang Source Type: research
Arsenic's shadowy influence: A systematic review of its carcinogenic role in gallbladder cancer
ConclusionThere is a strong link between arsenic exposure and gallbladder cancer or cholangiocarcinoma. Even chronic exposure to low-moderate amounts could lead to gallbladder carcinoma. These findings stress the need for more comprehensive and dedicated studies, to control arsenic water/soil levels and seek other preventive measures for this high mortality disease. (Source: Journal of Hepato-Biliary-Pancreatic Surgery)
Source: Journal of Hepato-Biliary-Pancreatic Surgery - April 2, 2024 Category: Surgery Authors: Anas Elgenidy,
Ramez M. Odat,
Horiah Amer Al ‐Ghorbany,
Hatim Nasruldin Shahin,
Ibrahim S. Abdel‐bary,
Roaa AbdulTawab AbdulHamid,
Amal Dhahab,
Moustafa Salem,
Youmna A. Negm,
Nada Mostafa El Attar,
Ahmed Assem Abdelfattah,
Mai M. Khaliel, Tags: SYSTEMATIC REVIEW Source Type: research
Long-term surgical outcomes of bile duct tumor thrombus versus portal vein tumor thrombus for hepatocellular carcinoma: a propensity score matching analysis
ConclusionAggressive hemihepatectomy provides an acceptable prognosis for HCC patients with macro-BDTT. Furthermore, the long-term surgical outcomes of HCC patients with macro-BDTT were significantly better than those of HCC patients with macro-PVTT. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - April 2, 2024 Category: Cancer & Oncology Source Type: research
Surgical interpretation of the WHO subclassification of intrahepatic cholangiocarcinoma: a narrative review
AbstractIntrahepatic cholangiocarcinoma (iCCA) has been subclassified by its gross morphology into the mass-forming (MF), periductal-infiltrating (PI), and intraductal growth (IG) types and their combinations. This classification correlates well with clinical features; for example, MF-iCCA has less lymph-node metastasis and a better prognosis than PI-iCCA. According to the recently accumulated evidence from histological investigations, the WHO classification endorsed a subclassification scheme in which iCCA cases are classified into small- and large-duct types. Small-duct iCCA is considered to originate from septal or smal...
Source: Surgery Today - April 2, 2024 Category: Surgery Source Type: research
