The effects of laparoscopic Roux-en-Y gastric bypass and one-anastomosis gastric bypass on glycemic control and remission of type 2 diabetes mellitus: study protocol for a multi-center randomized controlled trial (the DIABAR-trial)
DiscussionThe DIABAR-trial is one of the few randomized controlled trials primarily aimed to evaluate the glycemic response after the RYGB and OAGB in severe obese patients diagnosed with T2DM. Secondary aims of the trial are to contribute to a deeper understanding of the mechanisms that drive the remission of T2DM in severe obese patients by identification of microbial, immunological, and metabolic markers for metabolic response and to compare complications and side effects of RYGB and OAGB.Trial registrationClinicalTrials.govNCT03330756; date first registered: October 13, 2017. (Source: Trials)
Source: Trials - October 22, 2022 Category: Research Source Type: clinical trials
First in Human Study of a Monoclonal Antibody (SOL-116) Targeting BSSL (Bile Salt-Stimulated Lipase)
Condition: Rheumatoid Arthritis Interventions: Biological: SOL-116; Biological: Placebo Sponsors: Lipum AB; QPS Netherlands B.V. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2022 Category: Research Source Type: clinical trials
