Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity
This study will be the first randomized controlled trial to examine the effects of a Mediterranean diet, weight loss, or both on bile acid metabolism, the gut microbiome, and intestinal epithelial genes associated with carcinogenesis. This approach to CRC risk reduction may be especially important among African American/Blacks given their higher risk factor profile and increased CRC incidence.Trial registrationClinicalTrials.govNCT04753359. Registered on 15 February 2021. (Source: Trials)
Source: Trials - February 15, 2023 Category: Research Source Type: clinical trials
Associations of Fecal Bile Acid Profile and Intestinal Flora With Chronic Radiation Enteritis
Condition: Radiation Enteritis Intervention: Sponsor: Xijing Hospital of Digestive Diseases Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2023 Category: Research Source Type: clinical trials
