Retracted: Clinical Effect of Clarithromycin Combined with Tinidazole on Helicobacter pylori-Related Gastritis and Its Influence on COX-2 Expression
Biomed Res Int. 2024 Mar 20;2024:9783981. doi: 10.1155/2024/9783981. eCollection 2024.ABSTRACT[This retracts the article DOI: 10.1155/2021/4171019.].PMID:38550195 | PMC:PMC10977193 | DOI:10.1155/2024/9783981 (Source: Biomed Res)
Source: Biomed Res - March 29, 2024 Category: Research Authors: BioMed Research International Source Type: research
An all-in-one therapeutic platform for the treatment of resistant Helicobacter pylori infection
Biomaterials. 2024 Mar 21;308:122540. doi: 10.1016/j.biomaterials.2024.122540. Online ahead of print.ABSTRACTHelicobacter pylori (H. pylori) infection is a major cause of gastric diseases. Currently, bismuth-based quadruple therapy is widely adopted for eradicating H. pylori infection. However, this first-line strategy faces several challenges such as drug resistance, intestinal dysbacteriosis, and patients' poor compliance. To overcome these problems, an all-in-one therapeutic platform (CLA-Bi-ZnO2@Lipo) that composed of liposomes loading clarithromycin (CLA), Bi, and ZnO2 hybrid nanoparticles was developed for eradicatin...
Source: Biomaterials - March 27, 2024 Category: Materials Science Authors: Chao Sun Jia Huang Xiaoqian Guo Chenli Zhang Li Wei Ka Ioi Wong Ziyun Yang Gang Zhao Min Lu Weiyan Yao Source Type: research
An all-in-one therapeutic platform for the treatment of resistant Helicobacter pylori infection
Biomaterials. 2024 Mar 21;308:122540. doi: 10.1016/j.biomaterials.2024.122540. Online ahead of print.ABSTRACTHelicobacter pylori (H. pylori) infection is a major cause of gastric diseases. Currently, bismuth-based quadruple therapy is widely adopted for eradicating H. pylori infection. However, this first-line strategy faces several challenges such as drug resistance, intestinal dysbacteriosis, and patients' poor compliance. To overcome these problems, an all-in-one therapeutic platform (CLA-Bi-ZnO2@Lipo) that composed of liposomes loading clarithromycin (CLA), Bi, and ZnO2 hybrid nanoparticles was developed for eradicatin...
Source: Biomaterials - March 27, 2024 Category: Materials Science Authors: Chao Sun Jia Huang Xiaoqian Guo Chenli Zhang Li Wei Ka Ioi Wong Ziyun Yang Gang Zhao Min Lu Weiyan Yao Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
CONCLUSION: Compared with CYP3A4*1, CYP3A4*18 has a greater metabolism of FK506, clarithromycin and ketoconazole can inhibit both the enzymatic activities of CYP3A4*1 and CYP3A4*18, consequently affecting the metabolism of FK506 and the inhibitory on CYP3A4*1 is stronger.PMID:38523538 | DOI:10.2174/0113892002286019240315052145 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - March 25, 2024 Category: Drugs & Pharmacology Authors: Jinhua Wen Yuwei Xiao Menghua Zhao Chen Yang Weiqiang Hu Source Type: research
Prevalence of antibiotics, antibiotic resistance genes, and their associations in municipal wastewater treatment plants along the Yangtze River basin, China
Environ Pollut. 2024 Mar 20:123800. doi: 10.1016/j.envpol.2024.123800. Online ahead of print.ABSTRACTThe overuse and misuse of antibiotics have resulted in the pollution of antibiotics and antibiotic resistance genes (ARGs) in municipal wastewater treatment plants (WWTPs), posing threats to ecological security and human health. Thus, a comprehensive investigation was conducted to assess the occurrence, removal efficiency, and ecological risks of antibiotics, along with the diversity, abundance, and co-occurrence of ARGs, and their correlations in 13 WWTPs along the Yangtze River Basin. Among 35 target antibiotics, 23 antib...
Source: Environmental Pollution - March 22, 2024 Category: Environmental Health Authors: Yangyang Zhang Yifan Hu Xiuwen Li Linjun Gao Shuya Wang Shuyu Jia Peng Shi Aimin Li Source Type: research
Cutaneous < em > Mycobacterium Abscessus < /em > Infection Following Plastic Surgery: Three Case Reports
CONCLUSION: It is important to note that a long-term wound that does not heal, especially after plastic surgery, should raise suspicion for M. abscessus infection. The infection mechanism in these three patients may have been due to exposure to surgical equipment that was not properly sterilized or due to poor sterile technique by the plastic surgeon. To prevent such infections, it is important to ensure proper sterilization of surgical equipment and saline.PMID:38505806 | PMC:PMC10949168 | DOI:10.2147/CCID.S445175 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - March 20, 2024 Category: Dermatology Authors: Hongwei Shen Qiaomin Zhang Liang Peng Wen Ma Jingdong Guo Source Type: research
