Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
Conditions:   Otitis Media;   Tonsillitis;   Pharyngitis;   Bronchitis Interventions:   Drug: Clarithromycin DST (125 mg);   Drug: Clarithromycin DST (187.5 mg);   Drug: Clarithromycin DST (250 mg);   Drug: Clarithromycin Syrup (125 mg);   Drug: Clarithromycin Syrup (187.5 mg);   Drug: Clarithromycin Syrup (250 mg) Sponsor:   Grünenthal GmbH Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 11, 2019 Category: Research Source Type: clinical trials

Empirical vs Tailored Therapy for H. Pylori Infection
Conditions:   Helicobacter Pylori 23S rRNA Clarithromycin Resistance Mutation;   Helicobacter Pylori Infection Interventions:   Combination Product: triple therapy;   Combination Product: quadruple therapy;   Diagnostic Test: dual-priming oligonucleotide-based multiplex (DPO)-PCR test Sponsor:   Seoul National University Hospital Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 3, 2019 Category: Research Source Type: clinical trials

Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial
The objective of this trial is to establish the comparative effectiveness of endoscopic sinus surgery (ESS) or a prolonged course of antibiotics (clarithromycin) in adult patients with CRS in terms of symptomatic improvement and costs to the National Health Service compared with standard medical care (intranasal medication) at 6 months.Methods/designA three-arm parallel-group trial will be conducted with patients who remain symptomatic after receiving appropriate medical therapy (either in primary or secondary care). They will be randomised to receive: (1) intranasal medication plus ESS, (2) intranasal medication plus clar...
Source: Trials - April 29, 2019 Category: Research Source Type: clinical trials

Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme)
ConclusionThe expert panel review process resulted in agreement on key elements and an optimal design for the MACRO trial, considered most likely to be successful in terms of both recruitment potential and ability to establish best management of patients with CRS. (Source: Trials)
Source: Trials - April 23, 2019 Category: Research Source Type: clinical trials

Tailored H. Pylori Eradication Based on Clarithromycin Resistance
Conditions:   Helicobacter Pylori Infection;   Antibiotic Resistant Strain Interventions:   Drug: proton pump inhibitor, amoxicillin, clarithromycin;   Drug: proton pump inhibitor, amoxicillin, metronidazole Sponsor:   Kangdong Sacred Heart Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2019 Category: Research Source Type: clinical trials

A Study to Assess the Drug-Drug Interaction Between Bedaquiline and Clarithromycin in Healthy Adult Participants
Condition:   Healthy Interventions:   Drug: Bedaquiline;   Drug: Clarithromycin Sponsor:   Janssen Research & Development, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2019 Category: Research Source Type: clinical trials

A Comparison of Clarithromycin-based and Furazolidone-based Bismuth-containing Regimens for H. Pylori Eradication
Condition:   Helicobacter Pylori Interventions:   Drug: Furazolidone;   Drug: Clarithromycin Sponsor:   Shandong University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2018 Category: Research Source Type: clinical trials