Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease
CONCLUSIONS: Due to limited evidence, we are uncertain if text messaging reduces medication adherence, fatal and non-fatal cardiovascular events, and combined cardiovascular events in people with cardiovascular diseases when compared to usual care. Furthermore, text messaging may result in little or no effect on low-density lipoprotein cholesterol, blood pressure, and heart rate compared to usual care. The included studies were of low methodological quality, and no studies assessed the effects of text messaging in low-income countries or beyond the 12-month follow-up. Long-term and high-quality randomised trials are needed...
Source: Cochrane Database of Systematic Reviews - March 27, 2024 Category: General Medicine Authors: Julie Redfern Qiang Tu Karice Hyun Matthew A Hollings Nashid Hafiz Clara Zwack Caroline Free Pablo Perel Clara K Chow Source Type: research

Clinical and pharmacological factors influencing serum clozapine and norclozapine levels
Discussion:The use of CLO at recommended doses does not guarantee achieving therapeutic concentrations of CLO or NCLO. Women and nonsmokers were at the highest risk of having toxic CLO levels. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 27, 2024 Category: Drugs & Pharmacology Source Type: research

Effect of treatment with carteolol and latanoprost in newly diagnosed primary open-angle glaucoma on peripapillary vessel density
CONCLUSION: Carteolol had a better effect on vessel density than latanoprost.PMID:38516775 | DOI:10.5507/bp.2024.010 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - March 22, 2024 Category: Biomedical Science Authors: Lestak Jan Fus Martin Pitrova Sarka Source Type: research

Physician perceptions, attitudes, and strategies towards implementing guideline ‐directed medical therapy in heart failure with reduced ejection fraction. A survey of the Heart Failure Association of the ESC and the ESC Council for Cardiology Practice
ConclusionsAlthough comfort with implementing all four core drug classes in patients with HFrEF was high among physicians, a majority estimated implementation of GDMT in HFrEF to be low. We identified several important perceived clinical and non-clinical barriers that can be targeted to improve implementation. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - March 22, 2024 Category: Cardiology Authors: Gianluigi Savarese, Felix Lindberg, Ruxandra M. Christodorescu, Marc Ferrini, Thomas Kumler, Konstantinos Toutoutzas, Giuseppe Dattilo, Antoni Bayes ‐Genis, Brenda Moura, Offer Amir, Mark C. Petrie, Petar Seferovic, Ovidiu Chioncel, Marco M Tags: Research Article Source Type: research

Impact of heart rate changes during hospitalization on outcome in heart failure with preserved ejection fraction
ConclusionsIn hospitalized HFpEF patients, excessive HR dropping during hospitalization is associated with an increased risk of CV death or HF rehospitalization. These findings highlight the importance of HR monitoring and avoiding excessively slowing down HR in hospitalized HFpEF patients to reduce the risk of CV events. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 22, 2024 Category: Cardiology Authors: Dan Liu, Xiaotong Cui, Yamei Xu, Lei Xu, Zhonglei Xie, Shuai Yuan, Peng Wang, Yanyan Wang, Sanli Qian, Hui Gong, Peter Nordbeck, Jiefu Yang, Jingmin Zhou, Junbo Ge, Aijun Sun Tags: Original Article Source Type: research

Effects of Ivabradine on Myocardial Perfusion in Chronic Angina: A Prospective, Preliminary, Open-Label, Single-Arm Study
ConclusionIvabradine added to beta blockers was associated with a reduction in detectable myocardial ischemia by MPS in patients with CA.Infographic available for this article.Trial RegistrationThe trial has been retrospectively registered with the Brazilian Registry of Clinical Trials (REBEC) under the following number RBR-5fysqrh (date of registration: 30 November 2023).Graphical Abstract (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 22, 2024 Category: Cardiology Source Type: research

Postoperative atrial fibrillation (POAF) after cardiac surgery: clinical practice review
J Thorac Dis. 2024 Feb 29;16(2):1503-1520. doi: 10.21037/jtd-23-1626. Epub 2024 Feb 23.ABSTRACTPostoperative atrial fibrillation (POAF) after cardiac surgery is associated with elevated morbidity and mortality. Although current prediction models have limited efficacy, several perioperative interventions can reduce patients' risk of POAF. These begin with preoperative medications, including beta-blockers and amiodarone. Moreover, patients should be screened for preexisting atrial fibrillation (AF) so that concomitant surgical ablation and left atrial appendage occlusion can be performed in appropriate candidates. Intraopera...
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Orlando R Suero Ahmed K Ali Lauren R Barron Matthew W Segar Marc R Moon Subhasis Chatterjee Source Type: research