A Lengthy View of Everything that is Wrong with the Drug Development Industry
The primary problems with drug development are self-evident from the data. Firstly the process of drug development has become enormously more expensive over the past seventy years, a period in in which rapid technological progress has diminished the cost and effort required for any task in pharmacology and biotechnology by orders of magnitude. Secondly, the pace at which useful new medicines emerge in the clinic has diminished considerably, over the same period of technological progress in which the bounds of the possible have opened up enormously. The article I'll point out today is well worth reading, a lengthy treatment...
Source: Fight Aging! - March 12, 2024 Category: Research Authors: Reason Tags: Politics and Legislation Source Type: blogs
What will happen if you implement the Queen of Hearts in your Hospital?
This case was sent by Dr. Jean-christophe Reiters, an interventionalist in Belgium. He has been following the blog for 4 years.He has now implemented the Queen of Hearts in his hospital. He wanted to share one of the first cases.A 55 year old with no previous cardiac history presented with 3 hours of chest pain. The pain was persistent and reportedly still present at the time of the ECG.Here is the EKG:Smith: It looks like a reperfused inferior lateral OMI. (Inverted T-waves in inferior and lateral leads, with reciprocally upright (pseudo-hyperacute) T-waves in I and aVL. But if the pain ...
Source: Dr. Smith's ECG Blog - February 2, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs
GE HealthCare Announces Agreement to Acquire MIM Software
The Anticipated Acquisition Aligns to GE HealthCare’s Precision Care Strategy with the Goal of Strengthening the Company’s Digital Solutions Across Care Pathways
MIM Software Provides AI-Enabled Image Analysis and Workflow Tools Across Multiple Care Areas, Including Oncology, Urology, Neurology, and Cardiology
Today’s Agreement Reinforces GE HealthCare’s Commitment to Integrate Medical Imaging Products in Order to Deliver More Precise, Connected, and Efficient Care Across Disease States
GE HealthCare today announced it has entered into an agreement to acquire MIM Software, a global provider of medical imaging analy...
Source: EMR and HIPAA - January 25, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Andrew Nelson GE Healthcare Health IT Acquisitions Healthcare M&A MIM Software Peter Arduini Taha Kass-Hout Source Type: blogs
The Most Overhyped Technologies in Healthcare
The hype about technological development in healthcare should not blind us in terms of the probabilities and possibilities of today’s healthcare and the future of medicine. To remain objective and conscious but still optimistic, let’s look at the most overhyped technologies and keep in mind the realistic development opportunities in healing.
You know the saying: the pessimist says the glass is half empty, the optimist says it is half full, and, well, the cynic asks who drank the other half? I’m truly an optimist – especially when it comes to the future of medicine and healthcare, but we need to ask the uncom...
Source: The Medical Futurist - December 5, 2023 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine 3d printing robotics virtual reality wearables GC1 hype organs Source Type: blogs
What Counts as Evidence? A Uniquely Valuable Analysis of a Belgian Criminal Case Involving Euthanasia
Trudo Lemmens (University of Toronto), What Counts as Evidence? A Uniquely Valuable Analysis of a Belgian Criminal Case Involving Euthanasia (Reviewing Marc De Hert, Sien Loos, Sigrid Sterckx, Eric Thys& Kristoff Van Assche, Improving Control Over Euthanasia of Persons... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - November 16, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
STREAM -2, bats for “ half dose ” TNK-Tpa in elderly over pPCI
STREAM trial (New Engl J Med 2013) was a sort of paradigm-creating study, that made Pharamco-Invasive approach – PIA an authentic via-media strategy, trying to accure benefits from both lysis and PCI in the management of STEMI.
However, one question remained. Does PIA work safely in the elderly, where bleeding risks are higher? Do they tolerate the double whammy of P and I ? Both procedures keep the blood clotting process tentative for a prolonged period of time.
Emprical usage of half dose lysis is not new, is existingn, for more than 4 decades, right from streptokinase days.
Now the multi-center STREAM-2 ...
Source: Dr.S.Venkatesan MD - October 13, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs
Case of the Week 718
Welcome back to our first case of the month, with a special case from Idzi Potters and theInstitute of Tropical Medicine, Antwerp. The following structures were found in a bronchoalveolar lavage from a middle-aged Belgian patient with asthma who presented with increased shortness of breath. He reports no travel out-of-country and works as an administrator at an insurance company. He recently reported an insect infestation in his home.Video credits are for Monique Vatlet (CHU Ambroise Par é, Mons, Belgium).Identification? (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - June 5, 2023 Category: Parasitology Source Type: blogs
Missa Luba
We had a record of this in the house when I was growing up. I can ' t remember what I knew about it - maybe that it was from Africa, but maybe not which country. (I realise now that " from Africa " is not a meaningful description any more than describingpibroch orcerdd dant as " from Europe " would be). We had a lot of folk music in the house, so perhaps I saw it as folk music. And perhaps there is truth in that.I now have that same record in my house. The front of the record sleeve is shown above.It is on Spotify, and most of it is inThe Planet ' s Greatest African Music volume 2, dated ...
Source: Browsing - May 22, 2023 Category: Databases & Libraries Tags: music Source Type: blogs
The New Deal and Recovery, Part 27: Deposit Insurance
ConclusionPart 27: Deposit Insurance_____________________[1] To this list we might add a fourth item, noted by Golembe in a subsequentinterview, to wit: that the deposit " insurance " provided for by the 1933 Banking Act wasn ' t really insurance at all. Unlike genuine insurance policies, it covers depositors for losses regardless of whether the losses were due to recklessness on their or their banks ' part. And unlike genuine insurance funds, the FDIC ' s insurance " fund " is an accounting fiction, the truth being that the " premiums " it collects from banks go into the federal government ' s general coffers. " The gover...
Source: Cato-at-liberty - March 28, 2023 Category: American Health Authors: George Selgin Source Type: blogs
Transforming Integrated Care in the Community (TICC): blueprint
This report captures the key lessons of aproject undertaken by organisations in four European countries (UK, France, the Netherlands and Belgium) to explore what is involved in taking a highly successful innovation in one national context and applying it in others. The example of Buurtzorg was chosen because of its undoubted and extraordinary success in its country of origin, the Netherlands, where it has revolutionised community-based health and care services. Its achievements - improving care, the jobs of professionals providing care, and resource use - provided the inspiration for the organisations that came together as...
Source: Health Management Specialist Library - March 27, 2023 Category: UK Health Authors: The King ' s Fund Library Tags: Integrated care, collaboration and partnership Source Type: blogs
New Company, Velsera, Represents Summa Equity ’ s Vision to Improve Global Health Outcomes
New company advances precision health through data-driven solutions
New company Velsera was announced today at the J.P. Morgan Healthcare Conference in San Francisco, California. The vision for Velsera is supported by thematic-focused impact fund Summa Equity (Summa).
The promise of precision medicine is held back by barriers across routine health practice and discovery. Existing companies offer partial solutions, but no single company enables the unlocking of insights waiting to be revealed inside data – the status quo is siloed and disconnected. Velsera enables the democratization of omic data across clinical and ...
Source: EMR and HIPAA - January 23, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Calyx Gavin Nichols Global Health Outcomes Hans Cobben Health IT Acquisitions Healthcare M&A J.P. Morgan Healthcare Conference Omic Data Parexel Pierian Quintiles Seven Bridges Summa Summa Equi Source Type: blogs
World population likely reaches 8 billion by the end of the year
Human population is roughly 7,986,585,500 as of today. That’s about 13 million shy of 8 billion people. On average this year population has been growing at about 222,000 people every day.
The world’s population has doubled since 1974, the year ABBA won the Eurovision Song Contest with their song Waterloo.
It was half the 1974 number in 1927, the year of the first transatlantic phone service.
We numbered a mere billion in 1804 the year Napoleon Bonaparte was proclaimed Emperor of France.
It had taken from 1600 to that point for the estimated world population to have doubled to a billion, that was the year Englan...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 8, 2022 Category: Science Authors: David Bradley Tags: Science Source Type: blogs
World population likely to reach eight billion by the end of the year
The human population is roughly 7,986,585,500 as of today. That’s about 13 million shy of 8 billion people. On average this year population has been growing at about 222,000 people every day.
The world’s population has doubled since 1974, the year ABBA won the Eurovision Song Contest with their song Waterloo.
It was half the 1974 number in 1927, the year of the first transatlantic phone service.
We numbered a mere billion in 1804 the year Napoleon Bonaparte was proclaimed Emperor of France.
It had taken from 1600 to that point for the estimated world population to have doubled to a billion, that was the year En...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 8, 2022 Category: Science Authors: David Bradley Tags: Science Source Type: blogs
Nitazene Overdose Deaths on the Rise —The Iron Law of Prohibition Cannot Been Repealed
Jeffrey A. SingerLast week the Tennessee Department of Healthreported that overdose deaths from synthetic opioids classified asnitazenes have increased four ‐fold between 2019 and 2021. Nitazenes, like fentanyl and its analogs, aresynthetic opioids that were originally developed to treat pain. They are anywhere from 10 to 20 times more potent than fentanyl. As with overdoses from fentanyl and other opioids, overdoses from nitazenes can be reversed by administering naloxone, although the antidote might need to be given repeatedly to the victims.The first nitazenes were developed in the late 1950s by the Swiss drug make...
Source: Cato-at-liberty - September 23, 2022 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs
Chile and Latin America ’s Disposable Constitutions
Ian V ásquezChile votes this Sunday on a proposed, new constitution. It is a far-left document that would undermine fundamental rights and impoverish the country. Chileans should reject it. My colleagues and I have discussed the Chilean success story under the current constitution, the political conditions that gave rise to a constitutional convention that began meeting last year, and the problems with the proposed basic charterhere,here,here,here, andhere.In light of Chile ’s referendum, I reprint below a rough translation of anarticle I published in Peru in 2019 about Latin America ’s sorry tradition of frequently r...
Source: Cato-at-liberty - September 3, 2022 Category: American Health Authors: Ian V ásquez Source Type: blogs
