Arbaclofen-ER Decreases MS-Related Spasticity Arbaclofen-ER Decreases MS-Related Spasticity
Arbaclofen extended-release tablets can decrease spasticity related to multiple sclerosis, with a better safety profile than baclofen, new research suggests.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - September 16, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Teligent, Inc. Announces Health Canada Approval Of Three Baclofen Injection Products
BUENA, N.J., Aug. 25, 2016 -- (Healthcare Sales & Marketing Network) -- Teligent, Inc. (TLGT), a New Jersey-based specialty generic pharmaceutical company, today announced that its Estonian subsidiary, Teligent OÜ, has received three Abbreviated New ... Biopharmaceuticals, Generics, Regulatory Teligent, Baclofen (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 25, 2016 Category: Pharmaceuticals Source Type: news
Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms - de Witte LD, Dekker D, Veraart J, Kromkamp M, Kaasjager K, Vinkers CH.
BACKGROUND: Baclofen is increasingly prescribed for alcohol dependency. Subsequently, the risk of self-intoxication with this medicinal product is increasing. CASE DESCRIPTION: A 23-year-old man with a history of alcohol dependence was admitted to our hosp... (Source: SafetyLit)
Source: SafetyLit - August 6, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Baclofen Injection (Baclofen Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 19, 2016 Category: Drugs & Pharmacology Source Type: news
Well-known U of L researcher loses federal funding for study
A well-known University of Louisville researcher has lost federal funding for a nearly $1 million biomedical study because of concerns involving oversight and whether the data was valid.
According to the Kentucky Center for Investigative Reporting, Dr. Susan Harkema had been studying the effects of a muscle relaxer, called Baclofen, on patients who were undergoing treadmill therapy.
Funding for that $914,000 study was pulled in March by the National Institute on Disability, Independent Living and… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 12, 2016 Category: Pharmaceuticals Authors: Baylee Pulliam Source Type: news
Pharmacotherapy Utilisation in Alcohol Dependence
Conclusion
Pharmacotherapy in this cohort has the potential to increase success of clinical pathways but may be under-utilised in practice. This patient cohort is often difficult to engage and resistant to change. This may be compounded however by our lack of understanding of what therapies will be effective for each individual. This lack of stratification early in the treatment pathway may lead to a negative treatment outcome that disengages the patient. Looking ahead, translational research is required to identify novel therapeutic targets that can be developed into targeted therapies for alcohol dependence or broader al...
Source: Alcohol Research UK - June 8, 2016 Category: Addiction Authors: admin Tags: Alcohol Insights Source Type: news
Medtronic reorganizes its restorative therapies segment
Medtronic (NYSE:MDT) is shuffling the deck at its restorative therapies group as it looks to boost its ailing spine and neuromodulation businesses.
Fridley, Minn.-based Medtronic said yesterday that restorative therapies sales were up just 1% to $1.88 billion, including a -1% decline for its spine division at $737 million and a -5% slide to $494 million in neuromodulation.
Discussing the company’s fiscal 4th-quarter results with analysts yesterday, chairman & CEO Omar Ishrak said a “speed to scale” program in spine helped drive a steady cadence of new product launches, resulting in “a sequent...
Source: Mass Device - June 1, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: MassDevice Earnings Roundup Neuromodulation/Neurostimulation Spinal Wall Street Beat Medtronic Source Type: news
Baclofen (Baclofen Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 22, 2016 Category: Drugs & Pharmacology Source Type: news
FDA Warns Compounders of Contaminated APIs
The U.S. FDA has advised that certain lots of baclofen active pharmaceutical ingredient from China may be contaminated with particulates and should not be used to compound sterile injectable drugs. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 11, 2015 Category: Pharmaceuticals Source Type: news
FDA Warns of Contamination Risk for Some Baclofen API LotsFDA Warns of Contamination Risk for Some Baclofen API Lots
Certain lots of baclofen active pharmaceutical ingredient (API) may be at risk for contamination with particulates and should not be used to compound sterile injectable drugs, the FDA warns. News Alerts (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - December 10, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Alert Source Type: news
Baclofen Active Pharmaceutical Ingredient from Taizhou Xinyou Pharmaceutical and Chemical: FDA Statement - FDA Warns of Potential Contamination
The affected lots may potentially pose serious safety risks for U.S. patients who use or receive injectable drug products compounded with
the affected baclofen, especially when administered directly into the spinal column. (Source: FDA MedWatch)
Source: FDA MedWatch - December 10, 2015 Category: American Health Source Type: news
Therapeutic plasma exchange in poisoned patients
1 out of 5 stars
Therapeutic plasma exchange in poisoning: 8 years’ experience of a university hospital. Disel NR et al. Am J Emerg Med 2015 Oct;33:1391-1395.
Abstract
In therapeutic plasma exchange (TPE), blood is removed from the body, and plasma is separated from components such as RBCs, WBCs, and platelets. Those components are re-infused along with a replacement fluid such as fresh-frozen plasma or albumin. This procedure is usually used to removed pathological immunoglobulins in various conditions such as thrombotic thrombocytopenic purpura.
There have been some case reports and small case series on the us...
Source: The Poison Review - November 8, 2015 Category: Toxicology Authors: Leon Tags: Medical apheresis plasma exchange poisoned patient toxicology Source Type: news
What Are Treatments for Hiccups?
Discussion
Hiccups affect nearly everyone at sometime in their life but continue to be poorly understood and are usually considered a nuisance. The medical term for hiccups is singultus which comes from the Latin meaning “to be caught in the act of sobbing.” Hiccups are caused by a diaphragmatic spasm that causes a sudden inhalation that is interrupted by the spasmodic closure of the glottis that produces the characteristic hiccup sound. The ‘hic’ in hiccup occurs 4-60 times/minute and in adults has no physiological purpose, but in fetuses may help train inspiratory muscles for respiration after d...
Source: PediatricEducation.org - October 19, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
High-Dose Baclofen Supports Abstinence in AlcoholismHigh-Dose Baclofen Supports Abstinence in Alcoholism
High-dose baclofen supports abstinence among alcohol-dependent patients compared with placebo and is reasonably well tolerated. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - June 30, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news
baclofen, Gablofen, Lioresal
Title: baclofen, Gablofen, LioresalCategory: MedicationsCreated: 1/25/1999 12:00:00 AMLast Editorial Review: 6/8/2015 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - June 8, 2015 Category: Drugs & Pharmacology Source Type: news
