Statins side effects 'have been overstated', says study
Conclusion This is a complex study that provides a plausible explanation for the difference in reports of adverse effects of statins in RCTs and observational studies, some of which have suggested as many as 1 in 5 people get side effects from statins. However, we need to be aware of some limitations and unanswered questions: When people knew they were taking statins, they were more likely to report muscle pain than those not taking statins. But they were less likely to report muscle pain than in the first phase of the study, when they didn't know whether they were taking statins or placebo. We don't know why this is. ...
Source: NHS News Feed - May 3, 2017 Category: Consumer Health News Tags: Medication Heart/lungs Source Type: news

Statins side effects 'have been overstated,' says study
Conclusion This is a complex study that provides a plausible explanation for the difference in reports of adverse effects of statins in RCTs and observational studies, some of which have suggested as many as 1 in 5 people get side effects from statins. However, we need to be aware of some limitations and unanswered questions: When people knew they were taking statins, they were more likely to report muscle pain than those not taking statins. But they were less likely to report muscle pain than in the first phase of the study, when they didn't know whether they were taking statins or placebo. We don't know why this is. ...
Source: NHS News Feed - May 3, 2017 Category: Consumer Health News Tags: Medication Heart/lungs Source Type: news

' Suggestion' of Brain Changes on Statins by fMRI in STOMP'Suggestion' of Brain Changes on Statins by fMRI in STOMP
Despite few differences at cognitive testing for patients on atorvastatin vs placebo in the STOMP substudy,"small but significant" neuronal changes were seen on statins, their meaning unclear.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 23, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

New drug shows promise in preventing heart attacks
Conclusion This is a high-quality, well-conducted randomised controlled trial conducted in a very large number of people across multiple countries. To date, it's remained uncertain whether evolocumab reduces the risk of cardiovascular events. This study provides good evidence that the drug reduces the risk of major cardiovascular events in people with high LDL cholesterol levels, and with a high risk of having a cardiovascular event, who are already taking statins. The follow-up is limited to around two years, during which roughly 1 in 10 people experienced a cardiovascular event. The reduction in risk was shown to inc...
Source: NHS News Feed - March 20, 2017 Category: Consumer Health News Tags: Medication Heart/lungs Source Type: news

atorvastatin (Lipitor) vs. simvastatin (Zocor)
Title: atorvastatin (Lipitor) vs. simvastatin (Zocor)Category: MedicationsCreated: 3/2/2017 12:00:00 AMLast Editorial Review: 3/2/2017 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - March 2, 2017 Category: Cardiology Source Type: news

Caduet (Amlodipine Besylate, Atorvastatin Calcium) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 9, 2017 Category: Drugs & Pharmacology Source Type: news

Health Care Special Report: KU doc finds cancer hope
After years of treating patients, researching cancer and testing treatments, Tomoo Iwakuma made the discovery of his lifetime: Statins, typically used to lower cholesterol levels, could treat some types of cancer. An associate professor at the University of Kansas Medical Center, Iwakuma thinks that statins — such as brand names Crestor and Lipitor — could be used to treat 10 to 20 percent of cancer patients with a mutation in a tumor suppressor protein called p53. This mutation is found in… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - February 3, 2017 Category: Pharmaceuticals Authors: Elise Reuter Source Type: news

Make the Diagnosis: Guess the Vessel
(MedPage Today) -- Case Findings: A 50-year old male with family history significant for premature CAD presents with chest pain which started 3 hours ago. Blood pressure 150/90 mm Hg, HR 60/min. EKG in the emergency department is shown (see image below). Successful intervention of the culprit coronary artery is performed with one drug eluting stent. He is started on aspirin, ticagrelor, atorvastatin and metoprolol. Next morning he is found to be hypotensive to SBP 90s. Hemoglobin, creatinine and electrolytes are normal. Right groin access site is without any hematoma. A stat bedside echocardiogram reveals ejection fraction...
Source: MedPage Today Cardiovascular - January 30, 2017 Category: Cardiology Source Type: news

Liptruzet (Ezetimibe and Atorvastatin Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 9, 2016 Category: Drugs & Pharmacology Source Type: news

Lipitor (atorvastatin)
Title: Lipitor (atorvastatin)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/1/2016 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - November 1, 2016 Category: Cardiology Source Type: news

Lipitor (Atorvastatin Calcium) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 27, 2016 Category: Drugs & Pharmacology Source Type: news

Amgen cholesterol drug reduces arterial plaque buildup: study
(Reuters) - Amgen Inc said on Tuesday its potent new cholesterol fighter, Repatha, met the primary and secondary goals of a study designed to show it can decrease plaque buildup in heart arteries of patients already taking widely used statin drugs, such as Lipitor. (Source: Reuters: Health)
Source: Reuters: Health - September 20, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Can social media data lead to earlier detection of drug-related adverse events? - Duh MS, Cremieux P, Audenrode MV, Vekeman F, Karner P, Zhang H, Greenberg P.
PURPOSE: To compare the patient characteristics and the inter-temporal reporting patterns of adverse events (AEs) for atorvastatin (Lipitor( ®) ) and sibutramine (Meridia(®) ) in social media (AskaPatient.com) versus the FDA Adverse Event Reporting System... (Source: SafetyLit)
Source: SafetyLit - September 9, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Statins are 'safe, effective and should be used more widely'
Conclusion This study reviews evidence from randomised controlled trials (RCTs) and observational studies to better evaluate the effects and safety of statin therapy. It provides valuable data on the size of the benefits compared with the risks, informing a topic that has had much media coverage in recent times. The researchers highlight that the benefits of statin therapy for people at risk of cardiovascular disease events far outweigh any possible side effects. But it is still for a doctor and their patient to come to a conclusion about what the best treatment for them may be. If you have been prescribed a statin, it...
Source: NHS News Feed - September 9, 2016 Category: Consumer Health News Tags: QA articles Medication Heart/lungs Source Type: news

Atorvastatin Improves Arterial Stiffness in SLE (CME/CE)
(MedPage Today) -- Potential to reduce subclinical atherosclerosis (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - August 18, 2016 Category: Cardiology Source Type: news