Netherlands Cancer Institute Tests New Mesothelioma Therapy
Research for a new type of mesothelioma treatment is underway at the Netherlands Cancer Institute. Scientists are exploring a novel combination of existing medications for patients with BAP1 genetic mutations.
More than half of all mesothelioma patients show alterations in the BAP1 tumor-suppressor gene. An altered BAP1 gene allows for vulnerabilities that make specific treatments more effective. The combination treatment led to about a four-week increase in median survival.
Researchers have previously only explored the combination of zoledronic acid and tazemetostat in single cells and animal models. This late...
Source: Asbestos and Mesothelioma News - February 15, 2023 Category: Environmental Health Authors: Amy Edel Tags: Clinical Trials/Research/Emerging Treatments Mesothelioma Source Type: news
Court Rejects Johnson & Johnson ’s Bankruptcy Plan for Talc Lawsuits
A federal appeals court last week rejected an LTL Management bankruptcy filing, delivering a blow to the company’s plan to resolve thousands of talc lawsuits. The company is a Johnson & Johnson subsidiary.
The ruling effectively found the company’s bankruptcy was not filed in good faith. J&J said on Feb. 6 that it plans to appeal the U.S. Court of Appeals for the Third Circuit’s ruling.
“LTL initiated this process in good faith and our objective has always been to equitably resolve claims related to the company’s cosmetic talc litigation,” J&J wrote.
If denied on appeal, Joh...
Source: Asbestos and Mesothelioma News - February 7, 2023 Category: Environmental Health Authors: Amy Edel Tags: Asbestos Exposure Legal Mesothelioma Source Type: news
FDA reviews asbestos testing in cosmetics and powders
<img width="100" src="https://factor.niehs.nih.gov/sites/niehs-factor/files/styles/large/public/2020/3/science-highlights/asbestos/thumb886825.jpg?itok=L-2dVJ2e" /><br /><p>Christopher Weis and others discussed updating methods to test talc-containing products for asbestos and similar particles.</p>
(read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2023 Category: Environmental Health Source Type: news
Mesothelioma Treatment Uses Natural Immune Cells
This study provides support for the clinical evaluation of this IL2-based delivery system,” the authors wrote. Continued research with IL2 treatments in humans could lead to a new standard for mesothelioma therapy.
Using Cytokines Increases Effectiveness
Cytokine factories are delivery systems that invoke innate immune cells to fight tumors. Each drug “factory” consists of thousands of drug-producing cells contained in a microscopic gel-like bead. The study investigators used mice to model the efficacy of IL2 cytokine factories.
“The rapid clinical course of malignant mesothelioma necessitates the ...
Source: Asbestos and Mesothelioma News - February 1, 2023 Category: Environmental Health Authors: Amy Edel Tags: Clinical Trials/Research/Emerging Treatments Immunotherapy Mesothelioma Source Type: news
Brazil Wants to Abandon a 34,000-Ton Ship at Sea. It Would be an Environmental Disaster
Somewhere in the South Atlantic ocean right now, a 34,000-ton, 870-ft. aircraft carrier is floating aimlessly on the waves. The vessel, caught in an international dispute over its toxic contents, is about to become one of the biggest pieces of trash in the ocean.
The São Paulo, as the ship is known, has been stuck in limbo for five months. Brazil’s navy sold the 60-year-old vessel—the largest in its fleet—for scrap to a Turkish shipyard in 2021, and in August 2022, it set off for Turkey from a naval base in Rio de Janeiro. But while it was on the move, Turkey rescinded its permission to enter, sayi...
Source: TIME: Science - January 31, 2023 Category: Science Authors: Ciara Nugent Tags: Uncategorized brazil healthscienceclimate Londontime Oceans Source Type: news
Study Shows Opdivo, Yervoy Effective After Mesothelioma Surgery
This study tested the safety and efficacy of two drugs following mesothelioma surgery after cancer recurrence. The combination of immunotherapy drugs nivolumab and ipilimumab, known by the brand names Opdivo and Yervoy, was recently approved for mesothelioma.
The new treatment led to a 6-month survival of 87% in pleural mesothelioma patients. The 12-month survival rate was 74.2%.
“Nivolumab with ipilimumab has promising efficacy in treating recurrent MPM [malignant pleural mesothelioma] in the postoperative setting,” the authors wrote.
The authors also noted a higher rate of adverse events than in prior s...
Source: Asbestos and Mesothelioma News - January 30, 2023 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Immunotherapy Pleural Source Type: news
Hundreds of NHS buildings contain asbestos, says TUC
The union body wants the law to require all public buildings to remove the dangerous substance. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 27, 2023 Category: Consumer Health News Source Type: news
MPs urge asbestos company to pay £10m to fund cancer research
All-party group including peers backs campaign by victims ’ group, saying Cape ‘knowingly put people in danger’MPs and peers have written to one of the biggest manufacturers of asbestos calling on it to make a £10m donation towards mesothelioma research “for knowingly putting people in danger”.In a letter to Altrad, parent company of Cape, the all-party parliamentary group (APPG) on occupational safety and health says thatdocuments released after a long-running court battle show that Cape historically “provided misleading reassurance about the dangers of asbestos”.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - January 22, 2023 Category: Science Authors: Haroon Siddique Legal affairs correspondent Tags: Cancer House of Commons House of Lords Society Politics UK news Medical research Manufacturing sector Health Source Type: news
UK unions call in cancer expert over fears of asbestos risk to female teachers
Concerns at mesothelioma death rate trigger study to detect exposure to now banned material used in school buildingsThe threat of asbestos-related cancer to female teachers is to be examined after possible signs of an elevated risk of fatal illness.Trade unions are to work with one of the country ’s leading cancer experts on a study of the exposure women in their late-40s to mid-60s may have had to the material inside school buildings. It comes after researchers detected a possible increase in mesothelioma deaths among the group that could be statistically significant.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - January 15, 2023 Category: Science Authors: Michael Savage Policy Editor Tags: Schools Trade unions Cancer research UK news Science Society Education Teaching Medical research Health Politics Women Source Type: news
W.R. Grace offers $18.5M to settle Montana asbestos claims
The owner of a former vermiculite mine in northwestern Montana that spread harmful asbestos in and around the town of Libby has offered $18.5 million to settle the last of the state's claims for environmental damages, Gov. Greg Gianforte announced Tuesday. The proposed settlement was filed in W.R.…#grace #oregon #epa #lincolncounty #delaware #microscopic #superfund #montana #wrgrace #wrgraces (Source: Reuters: Health)
Source: Reuters: Health - January 11, 2023 Category: Consumer Health News Source Type: news
Baylor Study: Mesothelioma ‘Staged Surgical Approach’ Increases Survival
In this study, there were no immediate deaths following the first surgery, and all 14 patients proceeded to the second surgery. There were two patients – both starting with the EPP – who died within 90 days of the abdominal surgery.
“When considering bicavitary cytoreductive surgery for mesothelioma, we would recommend only performing ePD and avoiding EPP in this cohort of patients,” authors concluded.
Baylor Medical Center thoracic surgeon Dr. R. Taylor Ripley was the lead author of the study. One of the co-authors was surgical oncologist Dr. Paul Sugarbaker, brother of Dr. David Sugarbaker and a pioneer in ...
Source: Asbestos and Mesothelioma News - January 4, 2023 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Mesothelioma Source Type: news
UK Citizens Filing Asbestos Talc Claims In U.S. Courts
Residents of the United Kingdom have been among the growing number of personal injury plaintiffs filing lawsuits in U.S. courts, attributing their diagnoses of mesothelioma cancer to asbestos-contaminated talc.
That should come as no surprise. With the world’s highest per capita incidence rate of mesothelioma, the UK is contributing to the changing face of asbestos litigation in America.
While mesothelioma traced to occupational asbestos exposure among men is dropping, nonoccupational exposure leading to mesothelioma among women is rising.
Asbestos-contaminated talc, sometimes found in health and beauty products...
Source: Asbestos and Mesothelioma News - January 3, 2023 Category: Environmental Health Authors: Fran Mannino Tags: Asbestos Exposure Legal Mesothelioma Source Type: news
How cases of deadly asbestos cancer are rising in women
Recently qualified as a secretary, Susan Ellis, then aged 23, was excited to take on a position as a personal assistant in a leading firm of architects in Birmingham. (Source: the Mail online | Health)
Source: the Mail online | Health - January 3, 2023 Category: Consumer Health News Source Type: news
Multimodal Therapy of Epithelioid Pleural Mesothelioma Multimodal Therapy of Epithelioid Pleural Mesothelioma
This study describes a multimodal treatment approach to help improve overall survival in these patients.Translational Lung Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 2, 2023 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news
Avon Hit With $52.1M Verdict for Asbestos-Contaminated Talc
A California jury awarded $52.1 million to an Arizona woman diagnosed with mesothelioma cancer. The multimillion-dollar verdict combines damages against cosmetics giant Avon and a forklift manufacturer.
Attorneys for Rita-Ann Chapman said she had been using Avon talc products contaminated with asbestos for much of her life. Chapman is 76.
She blamed additional secondhand asbestos exposure on forklift maker Hyster Company. Her husband Gary handled asbestos products while working at Hyster.
Chapman won her case in California Superior Court earlier this month.
Mesothelioma is a rare cancer. Inhalation or ingestio...
Source: Asbestos and Mesothelioma News - December 21, 2022 Category: Environmental Health Authors: Fran Mannino Tags: Asbestos Exposure Legal Mesothelioma Source Type: news
