Effect of Fucoxanthin Administration on Thyroid Gland Injury Induced by Cadmium in Mice.
Abstract
The intervention effect of fucoxanthin, which is reportedly a powerful antioxidant, on cadmium-induced thyroid damage in mice was evaluated. Animals (N = 120) were divided into control group (given pure water, N = 20) and CdCl2-exposed group (given CdCl2 orally at a dose of 30 mg/kg body weight (bw)/day for 30 days, N = 100). Besides, the CdCl2-exposed group was divided into the following 5 groups (N = 20) to evaluate the intervention effect of fucoxanthin: (1) negative control group (NCG; animals were supplied with pure water); (2) positive control group (PCG; animals were supplied with 50 mg/kg ...
Source: Biological Trace Element Research - July 20, 2020 Category: Biology Authors: Yang H, Xing R, Liu S, Li P Tags: Biol Trace Elem Res Source Type: research
Analysis of the protective effects of γ-aminobutyric acid during fluoride-induced hypothyroidism in male Kunming mice.
CONCLUSION: Our findings support the assertion that GABA exerts therapeutic potential in hypothyroidism. The design and use of human GABA trials to improve therapeutic outcomes in hypothyroidism are now warranted.
PMID: 30676163 [PubMed - in process] (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - January 26, 2019 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
