Analysis of the protective effects of γ-aminobutyric acid during fluoride-induced hypothyroidism in male Kunming mice.
Analysis of the protective effects of γ-aminobutyric acid during fluoride-induced hypothyroidism in male Kunming mice. Pharm Biol. 2019 Dec;57(1):29-37 Authors: Yang H, Xing R, Liu S, Yu H, Li P Abstract CONTEXT: Compounds to treat hypothyroidism in the absence of cardiac side effects are urgently required. In this regard, γ-aminobutyric acid (GABA) has gained interest due to its anti-anxiolytic, antihypertensive and antioxidant properties, and reported benefits to the thyroid system. OBJECTIVE: We investigated the ability of GABA to ameliorate fluoride-induced thyroid injury in mice, a...
Source: Pharmaceutical Biology - January 26, 2019 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research