Aromatase inhibitor-induced arthralgia ameliorated by Mediterranean diet and active lifestyle guided by continuous glucose monitoring: a case report and review of the literature
Aromatase inhibitors (AIs) are a cornerstone adjuvant treatment of many hormone receptor-positive breast cancers, and nearly half of women taking aromatase inhibitors suffer from AI-induced arthralgia (AIA), also known as AI-associated musculoskeletal syndrome (AIMSS), for which there are limited evidence-based treatments. Pharmacologic management and complementary methods including supplements, exercise, physical therapy, yoga, acupuncture, and massage have all shown mixed results. Comprehensive diet and lifestyle strategies are understudied in AIA/AIMSS despite their disease-modifying effects across many chronic conditio...
Source: Frontiers in Oncology - February 1, 2024 Category: Cancer & Oncology Source Type: research
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer
Curr Drug Targets. 2024 Jan 12. doi: 10.2174/0113894501277556231221072938. Online ahead of print.ABSTRACTBreast cancer is a widespread condition that kills more women from cancer-related causes than any other type of cancer globally. Women who have estrogen-dependent, initial metastatic breast cancer frequently receive treatment with surgery, radiation therapy, and chemotherapy. They may also get more specialized treatments like tamoxifen or aromatase inhibitors (anastrozole or letrozole). The World Health Organisation reported in 2012 that by 2030, breast cancer will be more common worldwide. There are several phytochemic...
Source: Current Drug Targets - January 17, 2024 Category: Drugs & Pharmacology Authors: Zulfa Nooreen Sudeep Tandon Ankita Wal Awani Kumar Rai Source Type: research
Cancers, Vol. 16, Pages 344: Ocular Surface Side Effects of Novel Anticancer Drugs
naccare
Surgery, anticancer drugs (chemotherapy, hormonal medicines, and targeted treatments), and/or radiation are common treatment strategies for neoplastic diseases. Anticancer drugs eliminate malignant cells through the inhibition of specific pathways that contribute to the formation and development of cancer. Given the ability of such pharmacological medications to combat cancerous cells, their role in the management of neoplastic diseases has become essential. However, these drugs may also lead to undesirable systemic and ocular adverse effects due to cyto/neuro-toxicity and inflammatory reactions. Ocular surface...
Source: Cancers - January 13, 2024 Category: Cancer & Oncology Authors: Livio Vitiello Filippo Lixi Giulia Coco Giuseppe Giannaccare Tags: Review Source Type: research
Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: Cancer Control)
Source: Cancer Control - December 14, 2023 Category: Cancer & Oncology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research
Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research
Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research
Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research
Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research
Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial
Lancet Oncol. 2023 Dec 5:S1470-2045(23)00578-8. doi: 10.1016/S1470-2045(23)00578-8. Online ahead of print.ABSTRACTBACKGROUND: An increased risk of breast cancer is associated with high serum concentrations of oestradiol and testosterone in postmenopausal women, but little is known about how these hormones affect response to endocrine therapy for breast cancer prevention or treatment. We aimed to assess the effects of serum oestradiol and testosterone concentrations on the efficacy of the aromatase inhibitor anastrozole for the prevention of breast cancer in postmenopausal women at high risk.METHODS: In this case-control st...
Source: Cancer Control - December 9, 2023 Category: Cancer & Oncology Authors: Jack Cuzick Kim Chu Brian Keevil Adam R Brentnall Anthony Howell Nicholas Zdenkowski Bernardo Bonanni Sibylle Loibl Kaija Holli D Gareth Evans Steve Cummings Mitch Dowsett Source Type: research
Aromatase inhibitors: a useful additional therapeutic option for slowing down advanced bone age in boys with growth hormone deficiency
ConclusionsWhen used in addition to rhGH therapy in boys with GHD and advanced BA, AIs were observed to slow down the tempo of BA maturation after 1 year, compared to those who received rhGH treatment alone. AI therapy was found to be safe during the 1-year observation period and thus could be considered for preserving growth potential in these patients. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - December 1, 2023 Category: Endocrinology Source Type: research
EE81 Cost-Effectiveness of CDK 4/6I for the Treatment of Postmenopausal Patients With Advanced Breast Cancer HR-Positive, HER2-Negative From the Point of View of the Payer of the Public Health System in Panama
The aim of this study is to estimate the cost-effectiveness of ribociclib + letrozole, Abemaciclib + letrozole or ANAS (Anastrozole) versus palbociclib + letrozole in the treatment of HR-positive, HER2-negative advanced breast cancer patients in the first line of treatment from the perspective of the National Cancer Institute of Panama (ION). (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: O. Castillo-Fernandez, G. Sinta Source Type: research
