Contribution to the characterization of the seed endophyte microbiome of Argania spinosa across geographical locations in Central Morocco using metagenomic approaches
In conclusion, this first exploration of the argan seed endophyte microbiome demonstrated environmental influence on community structure. While facing limitations due to small sample sizes and lack of ecological metadata, it provides a foundation for future mechanistic investigations into how specific endophyte–host interactions shape argan adaptation across Morocco’s diverse landscapes. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - March 25, 2024 Category: Microbiology Source Type: research

Nanostructured Lipid Carriers of Donepezil Hydrochloride for the Treatment of Alzheimer's Disease
CONCLUSION: The DNZ-loaded NLCs, when administered via nasal route, showed markedly improved drug availability in the brain, suggesting an efficient drug delivery strategy to treat Alzheimer's disease.PMID:38445703 | DOI:10.2174/0115672050288659240229080535 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 6, 2024 Category: Neurology Authors: Avinash Tekade Ram Susar Gajanan Kulkarni Samiksha Surwade Anil Gaikwad Source Type: research

Nanostructured Lipid Carriers of Donepezil Hydrochloride for the Treatment of Alzheimer's Disease
CONCLUSION: The DNZ-loaded NLCs, when administered via nasal route, showed markedly improved drug availability in the brain, suggesting an efficient drug delivery strategy to treat Alzheimer's disease.PMID:38445703 | DOI:10.2174/0115672050288659240229080535 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 6, 2024 Category: Neurology Authors: Avinash Tekade Ram Susar Gajanan Kulkarni Samiksha Surwade Anil Gaikwad Source Type: research

Nanostructured Lipid Carriers of Donepezil Hydrochloride for the Treatment of Alzheimer's Disease
CONCLUSION: The DNZ-loaded NLCs, when administered via nasal route, showed markedly improved drug availability in the brain, suggesting an efficient drug delivery strategy to treat Alzheimer's disease.PMID:38445703 | DOI:10.2174/0115672050288659240229080535 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 6, 2024 Category: Neurology Authors: Avinash Tekade Ram Susar Gajanan Kulkarni Samiksha Surwade Anil Gaikwad Source Type: research

Nanostructured Lipid Carriers of Donepezil Hydrochloride for the Treatment of Alzheimer's Disease
CONCLUSION: The DNZ-loaded NLCs, when administered via nasal route, showed markedly improved drug availability in the brain, suggesting an efficient drug delivery strategy to treat Alzheimer's disease.PMID:38445703 | DOI:10.2174/0115672050288659240229080535 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 6, 2024 Category: Neurology Authors: Avinash Tekade Ram Susar Gajanan Kulkarni Samiksha Surwade Anil Gaikwad Source Type: research

Nanostructured Lipid Carriers of Donepezil Hydrochloride for the Treatment of Alzheimer's Disease
CONCLUSION: The DNZ-loaded NLCs, when administered via nasal route, showed markedly improved drug availability in the brain, suggesting an efficient drug delivery strategy to treat Alzheimer's disease.PMID:38445703 | DOI:10.2174/0115672050288659240229080535 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 6, 2024 Category: Neurology Authors: Avinash Tekade Ram Susar Gajanan Kulkarni Samiksha Surwade Anil Gaikwad Source Type: research

Molecules, Vol. 29, Pages 160: Fatty Acid Profiles and Biological Activities of the Vegetable Oils of Argania spinosa, Pinus halepensis and Pistacia atlantica Grown in Tunisia: A Preliminary Study
Vincenzo De Feo Several foods are used in both the nutraceutical and health sectors; vegetable oils, for example, can prevent the onset of numerous diseases. The properties of these oils are related to their chemical composition and primarily to the presence of fatty acids. The present work aimed to determine the chemical profiles of Argania spinosa, Pinus halepensis, and Pistacia altantica oils, used in traditional Tunisian foods, and to evaluate some biological properties. We evaluated their antioxidant, anti-enzymatic, antimicrobial, and anti-inflammatory properties. Linoleic acid was the main component of the thr...
Source: Molecules - December 27, 2023 Category: Chemistry Authors: Marwa Khammassi Giuseppe Amato Lucia Caputo Filomena Nazzaro Florinda Fratianni Habiba Kouki Ismail Amri Lamia Hamrouni Vincenzo De Feo Tags: Article Source Type: research

Chemical and Biochemical Features of Spinasterol and Schottenol
Adv Exp Med Biol. 2024;1440:45-55. doi: 10.1007/978-3-031-43883-7_3.ABSTRACTPhytosterols, which are produced in plants, are structurally similar to cholesterol. Their basic structures consist of a cyclo pentano-perhydrophenanthrene nucleus composed of 3 hexane rings and of a pentane ring with an alkyl side chain. There are around more than 250 phytosterols and related compounds that have been identified in natural resources. Among them, spinasterol and schottenol, its dihydro analog, are often found in seeds, and consequently in seed oils, and in other botanical parts of some plant families such as Sapotaceae, Cactaceae, a...
Source: Advances in Experimental Medicine and Biology - November 30, 2023 Category: Research Authors: Farid Khallouki Mohamed Ksila Imen Ghzaiel Soukaina Essadek Mounia Tahri Joutey Samah Maaloul Wafa Zennouhi Laila Benbacer Mohamed Bourhia Lhoussain Hajji Amira Zarrouk Leila Rezig Sandrine Rup-Jacques Raoudha Abdellaoui Taoufik Ghrairi Olfa Masmoudi-Kouk Source Type: research