Endologix, TriVascular Technologies ink $211m merger
Endologix (NSDQ:ELGX) and TriVascular Technologies (NSDQ:TRIV) yesterday said they plan to merge in a cash-and-stock deal worth $211 million.
If consummated, the deal would unite 2 of the stent graft market’s smaller players. Both companies makes devices for treating abdominal aortic aneurysms; Irvine, Calif.-based Endologix makes 2 lines of stent grants, the Nellix and AFX devices, while Santa Rosa, Calif.-based TriVascular makes the Ovation stent graft.
The deal, which values TriVascular at $9.10 per share, calls for TRIV shareholders to receive a to-be-determined combination of ELGX shares and cash equal to ...
Source: Mass Device - October 27, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: MassDevice Earnings Roundup Stent Grafts Endologix Inc. TriVascular Source Type: news
[Research Article] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysms in mice
Aortic aneurysms may form when smooth muscle cells cannot respond appropriately to external mechanical forces. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 20, 2015 Category: Science Authors: Yoshito Yamashiro, Christina L. Papke, Jungsil Kim, Lea-Jeanne Ringuette, Qing-Jun Zhang, Zhi-Ping Liu, Hamid Mirzaei, Jessica E. Wagenseil, Elaine C. Davis, Hiromi Yanagisawa Source Type: news
Endologix Announces FDA Approval of AFX(R)2 Bifurcated Endograft System
IRVINE, Calif., Oct. 12, 2015 -- (Healthcare Sales & Marketing Network) -- Endologix, Inc. (ELGX), developer and marketer of innovative treatments for aortic disorders, announced today that it has received U.S. Food and Drug Administration (FDA) approval f... Devices, Interventional, FDAEndologix, AFX2, Bifurcated Endograft, abdominal aortic aneurysm (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 12, 2015 Category: Pharmaceuticals Source Type: news
FDA clears Endologix’ AFX2 bifurcated stent graft
Endologix (NSDQ:ELGX) said it won FDA premarket approval for its AFX2 bifurcated endograft system for treating abdominal aortic aneurysms.
The system is the newest-generation of AFX endovascular AAA product from the Irvine, Calif.-based company. The new version of the device reduces delivery and deployment procedure steps and can facilitate percutaneous endovascular aneurysm repair through a low-profile 7F introducer.
“The AFX system is already uniquely positioned as the only anatomical fixation EVAR device on the market. With the approval of AFX2, we have taken a versatile platform and combined it with an easy to ...
Source: Mass Device - October 12, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Food & Drug Administration (FDA) Pre-Market Approval (PMA) Regulatory/Compliance Stent Grafts Stents Endologix Inc. Source Type: news
Fluoroquinolones May Increase Aortic Aneurysm Risk (CME/CE)
(MedPage Today) -- Doubling of relative risk observed (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 7, 2015 Category: Cardiology Source Type: news
MassDevice.com +3 | The top 3 medtech stories for October 5, 2015
Say hello to MassDevice +3, a bite-sized view of the top three medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 3 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry.
3. Medtronic touts 5-year Valiant stent graft data
Medtronic touted follow-up data from the Valor II study of its Valiant stent graft, saying patients with descending thoracic aortic aneurysms showed 94.8% freedom from aneurysm-related mortality at 5 years.
Fridley, Minn.-based Medtronic, which ...
Source: Mass Device - October 5, 2015 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 3 Source Type: news
Medtronic touts 5-year Valiant stent graft data
Medtronic (NYSE:MDT) today touted follow-up data from the Valor II study of its Valiant stent graft, saying patients with descending thoracic aortic aneurysms showed 94.8% freedom from aneurysm-related mortality at 5 years.
Fridley, Minn.-based Medtronic, which originally won PMA approval for Valiant in April 2011, said the results show the durability of the Valiant device. The Valor II study, a prospective, single-arm trial involving 160 patients in the U.S., met its primary safety and efficacy endpoints back in 2011 with an overall mortality rate of 12.6% and a 97% success rate at 12 months.
The follow-up data showe...
Source: Mass Device - October 5, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiovascular Clinical Trials Stent Grafts Medtronic Source Type: news
Cook Medical launches Advance salivary balloon catheter
Cook Medical said Monday it launched the Advance salivary duct balloon catheter designed to dilate structures in the submandibular and parotid salivary ducts.
The device is the Bloomington, Ind.-based company’s 1st high-pressure balloon specifically for salivary duct intervention.
“Stenosis of the salivary ducts can significantly impact a person’s quality of life. There is a clear unmet clinical need for more effective minimally invasive treatment options for salivary duct strictures. We are proud to provide clinicians with the Advance salivary duct balloon catheter set to help treat patients in the area of s...
Source: Mass Device - September 30, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Catheters Cook Medical Source Type: news
Bolton Medical wins CE Mark for Treo stent graft
Bolton Medical said today it won CE Mark approval in the European Union for its Treo abdominal stent-graft for treating abdominal aortic aneurysms.
The endovascular aneurysm repair device is designed as a modular 3-piece system with dual proximal fixation and a unique proximal clasping mechanism, the Sunrise, Fla.-based company said.
“We believe that in EVAR, the tri-modular strategy is the best approach. This is because it allows you to deliver a tailored solution to each patient by selecting specific components to precisely work in that individual anatomy,” R&D veep Scott Rush said in prepared remarks.
T...
Source: Mass Device - September 24, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Blog Bolton Medical Source Type: news
AAA IDE study expands, hopes to add Aortica software
Aortica said today that a physician-sponsored investigational device exemption study of abdominal aortic aneurysm-treating endografts gained FDA approval to introduce a new software-planning tool and expand the number of endografts in the study.
The trial is designed to assess new technology that could reduce the need for invasive surgeries in patients with aneurysms that are “too close to (or encompass) branch arteries that supply blood to vital organs,” the Bellevue, Wash.-based company said.
“In our study, we are introducing an algorithm that I call Patient Match Technology, which will dramatically s...
Source: Mass Device - September 18, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Clinical Trials Food & Drug Administration (FDA) Aortica Source Type: news
FDA OKs Cook’s low-profile Zenith Alpha stent graft
Cook Medical said it won premarket approval from the FDA for its Zenith Alpha thoracic endovascular stent graft designed for patients with isolated lesions of the descending thoracic aorta.
The approval came based on 2 pivotal clinical trials examining the safety and effectiveness of the graft in patients with aortic aneurysms or ulcers or with blunt traumatic aortic injuries, Cook said.
“Despite all the successes we’ve seen over the past few decades in endovascular aneurysm repair, we continue to be frustrated when we have to put a large sheath through iliac arteries that are smaller than the delivery system. Dev...
Source: Mass Device - September 17, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Food & Drug Administration (FDA) Regulatory/Compliance Stent Grafts Stents Surgical Vascular Cook Medical Source Type: news
Lombard Medical Names David Milne to Board of Directors
IRVINE, Calif., Sept. 8, 2015 -- (Healthcare Sales & Marketing Network) -- Lombard Medical Inc. (EVAR), a medical device company focused on endovascular aortic repair of abdominal aortic aneurysms, today announced that medical device executive and investor... Devices, Interventional, PersonnelLombard Medical, Aorfix, abdominal aortic aneurysm, AAA (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 8, 2015 Category: Pharmaceuticals Source Type: news
Endovascular Aortic Aneurysm Repair May Have Trade-offsEndovascular Aortic Aneurysm Repair May Have Trade-offs
Compared with open repair, mortality rates were lower for patients with endovascular repair through the third year of follow-up, when the pattern shifted. Medscape Medical News (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 4, 2015 Category: Surgery Tags: General Surgery News Source Type: news
Emory, Georgia Tech biomedical researchers get $10 million in grants
Emory University and Georgia Tech researchers recently received two large grants to further their collaborative research.
On Sept. 1, the National Institutes of Health announced a $8.9 million grant for Emory and Georgia study that will examine how reactive oxygen species and inflammation can be both necessary for blood vessels to function, but also detrimental in excess. The team's goal is to use this research to develop new preventive approaches to conditions like atherosclerosis and aortic aneurysms.
And… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 2, 2015 Category: Pharmaceuticals Authors: Ellie Hensley Source Type: news
Current AAA screening strategies may miss the mark
Ultrasound screening programs for abdominal aortic aneurysms (AAA) that focus...Read more on AuntMinnie.comRelated Reading:Vascular surgery society cautions use of US in AAA, June 2, 2015USPSTF finalizes AAA screening recommendations, June 24, 2014EHR alerts boost participation in AAA screening, February 12, 2014USPSTF revises stance on ultrasound AAA screening, January 28, 2014Longer US surveillance intervals fine for men with small AAAs, February 26, 2013 (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 21, 2015 Category: Radiology Source Type: news
