Antiphospholipid Antibodies and Bleeding From Renal BiopsyAntiphospholipid Antibodies and Bleeding From Renal Biopsy
A study identified the clinical and histologic risk factors for bleeding after renal biopsy in patients with lupus nephritis. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - July 16, 2014 Category: Rheumatology Tags: Rheumatology Viewpoint Source Type: news
Headaches, fatigue, dizziness and memory problems: Hughes Syndrome explained
AS PART of Hughes Syndrome Awareness Month, experts explain the little-known disease, also known as Antiphospholipid Syndrome and more common than Parkinson's and multiple sclerosis, and advise what to do if you think might be at risk (Source: Daily Express - Health)
Source: Daily Express - Health - May 20, 2014 Category: Consumer Health News Source Type: news
Neonatal Antiphospholipid Syndrome
Antiphospholipid antibody syndrome (APS) during pregnancy may result in pregnancy morbidity and passive transfer of antibodies to the fetus, resulting in an increased risk of prematurity, intrauterine growth restriction, thrombocytopenia, and developmental delay. Antiphospholipid antibodies may have an impact on neurodevelopment during fetal life. Although rare, persistence of these antibodies in the neonate may lead to thromboembolism, particularly if there is a concurrent infection and/or inherited thrombophilic disorders. Affected pregnant women need to be identified early during gestation so that they can have close mo...
Source: NeoReviews recent issues - May 1, 2014 Category: Pediatrics Authors: Magalhaes, C. S., Suppo de Souza Rugolo, L. M., Trindade, C. E. P. Tags: Articles Source Type: news
TLC Immunostaining for Detection of “Antiphospholipid” Antibodies
Thin-layer chromatography (TLC) is a nonquantitative technique, which has been employed in the detection of antiphospholipid (aPL) antibodies. Antiphospholipid syndrome (APS) is the most frequently acquired thrombophilia, characterized by thrombosis and obstetric manifestations associated to an autoimmune trait, represented by the positivity of antiphospholipid (aPL) antibodies. Immunoassays for anticardiolipin (aCL) and anti-β2 glycoprotein I (aβ2GPI) antibodies and clotting tests for lupus anticoagulant (LA) represent the standard tests for the routine detection of aPL. The term “seronegative APS” h...
Source: Springer protocols feed by Immunology - February 7, 2014 Category: Allergy & Immunology Source Type: news
Measurement of Malondialdehyde, Glutathione, and Glutathione Peroxidase in SLE Patients
Oxidative stress contributes to chronic inflammation of tissues and plays a central role in immunomodulation, which may lead to autoimmune diseases such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome. Markers of oxidative damage include malondialdehyde (MDA), antioxidant scavengers as glutathione (GSH), and glutathione peroxidase (GSH Px), which all correlate well with SLE disease activity. Amelioration of some clinical manifestations of SLE may be expected by targeting lipid peroxidation with dietary or pharmacological antioxidants. (Source: Springer protocols feed by Immunology)
Source: Springer protocols feed by Immunology - February 7, 2014 Category: Allergy & Immunology Source Type: news
Laboratory Tests for the Antiphospholipid Syndrome
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent vascular thrombosis (VT) and/or pregnancy morbidity (PM) in the presence of persistent antiphospholipid antibodies (aPL), detected by lupus anticoagulant (LA), anticardiolipin (aCL) antibody, and/or anti‐β2 glycoprotein I (aβ2GPI) antibody assays. These aPL, considered to be diagnostic markers and pathogenic drivers of APS, are a heterogeneous group of antibodies directed against anionic phospholipids, phospholipid-binding plasma proteins, and phospholipid–protein complexes. Although APS is currently considered as a s...
Source: Springer protocols feed by Immunology - February 7, 2014 Category: Allergy & Immunology Source Type: news
IgA Antiphospholipid Antibodies: Growing Clinical RelevanceIgA Antiphospholipid Antibodies: Growing Clinical Relevance
Testing for these autoantibodies may identify additional patients with clinical features of antiphospholipid antibody syndrome. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - January 17, 2014 Category: Rheumatology Tags: Rheumatology Viewpoint Source Type: news
Antiphospholipid Syndrome
Title: Antiphospholipid SyndromeCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 1/10/2014 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - January 10, 2014 Category: Rheumatology Source Type: news
Biomarker Predicts Poor Pregnancy Outcomes in Lupus, APLBiomarker Predicts Poor Pregnancy Outcomes in Lupus, APL
Angiogenic factor dysregulation early in pregnancy can predict pre-eclampsia and poor fetal and maternal outcomes, enabling early intervention in women with lupus or antiphospholipid syndrome (APL). Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 29, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Aspirin Prophylaxis Adequate for Antiphospholipid AntibodiesAspirin Prophylaxis Adequate for Antiphospholipid Antibodies
Adding warfarin to aspirin doesn't seem to improve thromboprophylaxis in patients with antiphospholipid antibodies (aPL), according to results from the ALIWAPAS study. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 22, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Invasive Aspergillosis vs Antiphospholipid SyndromeInvasive Aspergillosis vs Antiphospholipid Syndrome
Invasive aspergillosis is a frequently missed diagnosis. This case study tells why. American Journal of Critical Care (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 24, 2013 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news
Antiphospholipid Antibodies and Increased Stillbirth RiskAntiphospholipid Antibodies and Increased Stillbirth Risk
Women with increased antiphospholipid antibody levels face a threefold increased risk of stillbirth, a new study shows. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 19, 2013 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news
Genetics Home Reference: antiphospholipid syndrome
(Source: NLM General Announcements)
Source: NLM General Announcements - June 13, 2013 Category: Databases & Libraries Source Type: news
Rituximab for the Antiphospholipid Antibody SyndromeRituximab for the Antiphospholipid Antibody Syndrome
Dr. Kevin Deane comments on a pilot study of rituximab for the treatment of antiphospholipid syndrome. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2013 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news
Revised Article-Antiphospholipid Antibody Syndrome
Antiphospholipid antibody syndrome is an autoimmune disorder. (Source: National Heart, Lung, and Blood Institute Health Topics)
Source: National Heart, Lung, and Blood Institute Health Topics - May 23, 2012 Category: Consumer Health News Source Type: news
