Antioxidant for Taxane-Induced Neuropathy Antioxidant for Taxane-Induced Neuropathy
Be careful with antioxidants. Research finds that acetyl-L-carnitine worsened taxane-associated peripheral neuropathy.Journal of the National Cancer Institute (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 3, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news
Role of oxidative stress and antioxidant therapy in acute and chronic phases of sulfur mustard injuries: a review - Beigi Harchegani A, Khor A, Tahmasbpour E, Ghatresamani M, Bakhtiari Kaboutaraki H, Shahriary A.
Sulfur mustard (SM) is a chemical compound that preferentially targets ocular, cutaneous and pulmonary tissues. Although pathologic effect of SM has been extensively considered, molecular and cellular mechanism of its toxicity, especially at the chronic ph... (Source: SafetyLit)
Source: SafetyLit - July 11, 2018 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity
Mitochondria are integral to cellular energy metabolism and ATP production and are involved in regulating many cellular processes. Mitochondria produce reactive oxygen species (ROS), which not only can damage cellular components but also participate in signal transduction. The kinase ATM, which is mutated in the neurodegenerative, autosomal recessive disease ataxia-telangiectasia (A-T), is a key player in the nuclear DNA damage response. However, ATM also performs a redox-sensing function mediated through formation of ROS-dependent disulfide-linked dimers. We found that mitochondria-derived hydrogen peroxide promoted ATM d...
Source: Signal Transduction Knowledge Environment - July 10, 2018 Category: Science Authors: Zhang, Y., Lee, J.-H., Paull, T. T., Gehrke, S., DAlessandro, A., Dou, Q., Gladyshev, V. N., Schroeder, E. A., Steyl, S. K., Christian, B. E., Shadel, G. S. Tags: STKE Research Articles Source Type: news
How Scientists Are Testing Cancer Drugs to Slow Down Aging
Aging is a perfectly natural process, but that doesn’t mean that humans won’t try everything in their power to slow it down. In recent years, researchers who study aging have become intrigued by the idea of slowing the march of time by ridding the body of its population of older cells.
In a new study published in Nature Medicine, scientists led by Dr. James Kirkland, director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic, show that the proportion of older, aging cells in mice is indeed related to aging-related symptoms, from frailty to lower endurance and slower walking speeds. Kirkland and his ...
Source: TIME: Health - July 9, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Aging healthytime Innovation Health Source Type: news
Synthesis of tetrapeptides and screening of their antioxidant properties
(Bentham Science Publishers) Tetrapeptide Pro-Ala-Gly-Tyr (PAGY) and its analogues, namely, Pro-Ser-Gly-Tyr (PSGY), Pro-Ala-Phe-Tyr (PAFY), Pro-Phe-Phe-Tyr (PFFY) and Pro-Ala-Ile-Tyr (PAIY), were successfully synthesized via a solid phase peptide synthesis method with the Fmoc/t-Bu strategy. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 5, 2018 Category: Biology Source Type: news
Antioxidant supplements don't improve sperm quality, new study finds
The large clinical trial of 174 couples across eight fertility centers in America - one of the biggest trials to date - saw 'slight' changes after three months, but not enough to make a difference. (Source: the Mail online | Health)
Source: the Mail online | Health - July 2, 2018 Category: Consumer Health News Source Type: news
Antioxidant supplements do NOT improve sperm quality, major study finds
The large clinical trial of 174 couples across eight fertility centers in America - one of the biggest trials to date - saw 'slight' changes after three months, but not enough to make a difference. (Source: the Mail online | Health)
Source: the Mail online | Health - July 2, 2018 Category: Consumer Health News Source Type: news
Depression and anxiety symptoms are associated with prooxidant-antioxidant balance: a population-based study - Shafiee M, Ahmadnezhad M, Tayefi M, Arekhi S, Vatanparast H, Esmaeili H, Moohebati M, Ferns GA, Mokhber N, Arefhosseini SR, Ghayour-Mobarhan M.
BACKGROUND: Depression and anxiety are significantly associated with systemic inflammation. Moreover, oxidative stress resulting from a disturbance in the prooxidant-antioxidant balance is linked to inflammation-related conditions. Therefore, depression/an... (Source: SafetyLit)
Source: SafetyLit - July 2, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Antioxidant supplements fail to improve sperm quality in infertile men
(European Society of Human Reproduction and Embryology) Despite many study results suggesting that antioxidants have a positive effect on abnormal sperm parameters associated with male infertility, a large US clinical trial of 174 couples has found that an antioxidant formulation taken daily by the male partner for a minimum of three months made no difference to sperm concentration, motility or morphology, nor to the rate of DNA fragmentation. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 2, 2018 Category: Biology Source Type: news
Supplemental antioxidants may reduce exacerbations in cystic fibrosis
(American Thoracic Society) An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis (CF), according to new research published online in April in the American Journal of Respiratory and Critical Care Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 2, 2018 Category: International Medicine & Public Health Source Type: news
How Rioja may prevent cancer: Antioxidant in red wine halts the protein that causes tumours
Researchers from the Federal University of Rio de Janeiro found an antioxidant, resveratrol, in the tipple stops the formation of protein clumps that are found in 50 per cent of tumours. (Source: the Mail online | Health)
Source: the Mail online | Health - June 29, 2018 Category: Consumer Health News Source Type: news
How to live longer: Add this spice to your meals to increase your life expectancy
HOW TO live longer: Research over the years has found some simple changes to your lifestyle can make for a longer and more satisfying lifespan. Certain foods you eat can help increase your life expectancy, and one recommended by experts to include in your diet is an antioxidant-boosting spice. (Source: Daily Express - Health)
Source: Daily Express - Health - June 25, 2018 Category: Consumer Health News Source Type: news
New Treatment Prevents Formation of Cystine Stones, a Type of Kidney Stone, in Mice
The antioxidant α-lipoic acid was shown to prevent the formation of cystine stones in mice. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news
Antioxidant Cuts Hearing Loss in Cisplatin-Treated Kids
(MedPage Today) -- 50% reduction with no loss of anticancer efficacy (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - June 20, 2018 Category: Hematology Source Type: news
11 Best Foods For Your Immune System
The following story is excerpted from TIME’s special edition, 100 Most Healing Foods, which is available in stores, at the Meredith Shop and at Amazon.
Vitamin C has a reputation for being a feel-good nutrient, so it will come as no surprise that this list is full of foods with high levels of it. In the body, vitamin C behaves as an antioxidant, which means it protects cells from free-radical damage. Consuming it also helps the body better absorb iron, which is critical for normal immune-system function.
Although foods high in vitamin C won’t stop your flu symptoms, eating them regularly may help prevent...
Source: TIME: Health - June 19, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized Diet/Nutrition healthytime Source Type: news
