ID specialist input improves outcomes for outpatient parenteral antimicrobial therapy
(Infectious Diseases Society of America) An infectious diseases specialist should review all orders for outpatient IV antimicrobial therapy and adjust as needed, suggest new guidelines released by the Infectious Diseases Society of America (IDSA). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 13, 2018 Category: Infectious Diseases Source Type: news

Low Recurrence With Shortened IV Abx Course in GBS Bacteremia
THURSDAY, Oct. 11, 2018 -- For infants with uncomplicated, late-onset group B Streptococcus (GBS) bacteremia, a shortened intravenous (IV) course of antibiotic therapy is sometimes prescribed and is associated with low rates of disease recurrence... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 11, 2018 Category: Pharmaceuticals Source Type: news

Emergency department sepsis screening tool decreases time to antibiotics in patients with sepsis
The purpose of this study was to evaluate the impact of a sepsis screening tool implemented in an academic medical center ED on compliance with the 3-hour sepsis bundle. Although implementation of an ED sepsis screening tool did not increase 3-hour bundle compliance, it did increase the proportion of patients receiving timely antimicrobial therapy and demonstrated a trend towards decreased mortality. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 29, 2018 Category: Consumer Health News Source Type: news

Extended- vs Narrow-Spectrum Antibiotics in Appendicitis Extended- vs Narrow-Spectrum Antibiotics in Appendicitis
What is the best choice of antibiotic therapy for uncomplicated appendicitis in children? Dr Lowenfels comments on a study published in Annals of Surgery.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2018 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

GI Dynamics wins FDA nod for pivotal US EndoBarrier trial
GI Dynamics (ASX:GID) said today it won FDA investigational device exemption approval to launch a pivotal trial of its EndoBarrier device designed for treating patients with type 2 diabetes and obesity, pending Institutional Review Board approval. The EndoBarrier device is a plastic gut sleeve designed to prevent the absorption of nutrients from food as it exits the stomach and enters the intestinal tract to treat type 2 diabetes and obesity, the Lexington, Mass.-based company said. The approval is a boon for the company, which has faced a number of hurdles with its device over the past few years, including shutting do...
Source: Mass Device - August 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Diabetes Food & Drug Administration (FDA) Regulatory/Compliance Weight loss GI Dynamics Source Type: news

Outpatient parenteral antibiotic therapy system saves costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - August 1, 2018 Category: Drugs & Pharmacology Source Type: news

Rapid genetic testing can prevent hearing loss in newborns treated for sepsis
(European Society of Human Genetics) More than a million neonatal deaths worldwide each year are estimated to be due to sepsis. Many patients receive antibiotic therapy during their hospital stay, but babies with a specific genetic change can suffer irreversible hearing loss as a result. Now, a rapid test for distinguishing those infants who will have this adverse reaction to gentamicin has been developed. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 14, 2018 Category: Infectious Diseases Source Type: news

Bone apetit: How bacteria eat bone to sustain invasive infection
(American Society for Microbiology) Researchers from Vanderbilt University Medical Center have determined the metabolic pathway that Staphylococcus aureus use to survive in bones. Invasive S. aureus infections frequently occur in the bone and are notoriously resistant to antimicrobial therapy. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7-11 in Atlanta, Ga. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 8, 2018 Category: Biology Source Type: news

Most Premature Infants Receive Early Antibiotics
TUESDAY, May 29, 2018 -- Most premature infants receive empirical antibiotic therapy, according to a study published online May 25 in JAMA Network Open. Dustin D. Flannery, D.O., from the Children ' s Hospital of Philadelphia, and colleagues examined... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 30, 2018 Category: Pharmaceuticals Source Type: news

Each hour of delay in detecting abnormal lactates in patients with sepsis increases the odds of in-hospital death
(Elsevier) Because of a known association between elevated lactate levels and increased mortality, sepsis guidelines mandate that lactate levels should be tested soon after the onset of sepsis. A new study in the journal CHEST ® found that a significant proportion of patients with suspected sepsis do not have their lactates measured within the recommended timeframe. These patients experienced delayed antibiotic therapy and IV fluid administration, as well as increased risk of in-hospital death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 24, 2018 Category: International Medicine & Public Health Source Type: news

Evaluating the appropriateness of antimicrobial treatment in hospitalized patients: a comparison of three methods
This research article concluded that rates of appropriateness of antimicrobial therapy varied between evaluation methods, with low to moderate agreement between the different methods. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 9, 2018 Category: Consumer Health News Source Type: news

Antibiotic therapy for preventing infections in people with acute stroke
This review article concludes preventive antibiotics had no effect on functional outcome or mortality, but significantly reduced the risk of ' overall ' infections. This reduction was driven mainly by prevention of urinary tract infection; no effect for pneumonia was found. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 2, 2018 Category: Consumer Health News Source Type: news

New infection prevention tool improve transparency and standardization of practice
(European Society of Clinical Microbiology and Infectious Diseases) Researchers developed a new color-coded visual tool called Infection Risk Scan, or IRIS, which is set to make it easier for healthcare workers to measure in which areas a hospital complies with guidelines and where it needs to implement measures to improve infection control and the use antimicrobial therapies, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 20, 2018 Category: Biology Source Type: news

Duration of Antibiotics Often Exceeds Guidelines for Sinusitis
THURSDAY, March 29, 2018 -- The durations of most courses of antibiotic therapy for adult outpatients with sinusitis exceed guideline recommendations, according to a research letter published online March 26 in JAMA Internal Medicine. Laura M. King,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 29, 2018 Category: Pharmaceuticals Source Type: news

Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome
This research article concludes that mortality from sepsis is influenced by multiple factors. The study was unable to demonstrate that inactive AMT had an effect on mortality in sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 28, 2018 Category: Consumer Health News Source Type: news