Rotavirus vaccine clinical trials: a cross-sectional analysis of clinical trials registries
ConclusionsMapping rotavirus vaccine clinical trial activity using data from the WHO ICTRP beneficial provides valuable information on planned, ongoing, or completed trials for researchers, funders, and healthcare decision-makers. Despite the high rotavirus disease burden in low- and middle-income countries, including Africa, there is minimal clinical trial activity related to the condition on the continent. The clinical trial registries as a valuable tool to share interim results of the trials. (Source: Trials)
Source: Trials - November 17, 2022 Category: Research Source Type: clinical trials

Community-based, Controlled, Open-label, Cluster-randomized Trial for the Reduction of Chronic Malnutrition in Children Under Two Years of Age, With Three Intervention Arms Grouped by Clusters, in Two Provinces in Southern Angola, Hu íla and Cunene.
Condition:   Malnutrition, Child Interventions:   Dietary Supplement: Nutritional Supplementation;   Behavioral: Money transfers;   Behavioral: Standard intervention Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   Universidade Mandume Ya Ndemufayo;   Fundo de Apoio Social;   Instituto de Salud Carlos III;   Acción Contra el Hambre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 7, 2022 Category: Research Source Type: clinical trials

Impact of the Maternal and Child Health handbook in Angola for improving continuum of care and other maternal and child health indicators: study protocol for a cluster randomised controlled trial
This study is a cluster randomised controlled trial involving public healthcare facilities across all the municipalities located in Benguela Province, Angola. All women who go to participating healthcare facilities and with confirmed pregnancy around the beginning of the trial period will be included in the study. Women will be randomised according to the municipality where their primary maternity and/or childcare services are located. The intervention package will consist of MCH handbook distribution at all public healthcare facilities, MCH handbook utilisation training for healthcare providers and community mobilisation ...
Source: Trials - August 23, 2020 Category: Research Source Type: clinical trials

The SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT) to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission in low risk, non-severe COVID-19 patients in the first 48 hours after symptoms onset: A structured summary of a study protocol for a randomized control pilot trial
AbstractObjectivesThe primary objective is to determine the efficacy of a single dose of ivermectin, administered to low risk, non-severe COVID-19 patients in the first 48 hours after symptom onset to reduce the proportion of patients with detectable SARS-CoV-2 RNA by Polymerase Chain Reaction (PCR) test from nasopharyngeal swab at day 7 post-treatment.The secondary objectives are:To assess the efficacy of ivermectin to reduce the SARS-CoV-2 viral load in the nasopharyngeal swab at day 7 post treatment.To assess the efficacy of ivermectin to improve symptom progression in treated patients.To assess the proportion of seroco...
Source: Trials - June 7, 2020 Category: Research Source Type: clinical trials