The Anesthesiologists ’ Perception of Malignant Hyperthermia and Availability of Dantrolene in China: A Cross-Sectional Survey
(Source: Risk Management and Healthcare Policy)
Source: Risk Management and Healthcare Policy - March 28, 2024 Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research

OXIDATIVE study: A pilot prospective observational cohort study protocol examining the influence of peri-reperfusion hyperoxemia and immune dysregulation on early allograft dysfunction after orthotopic liver transplantation
by Elizabeth A. Wilson, Anna Woodbury, Kirsten M. Williams, Craig M. Coopersmith Early allograft dysfunction (EAD) is a functional hepatic insufficiency within a week of orthotopic liver transplantation (OLT) and is associated with morbidity and mortality. The etiology of EAD is multifactorial and largely driven by ischemia reperfusion injury (IRI), a phenomenon characterized by oxygen scarcity followed by paradoxical oxidative stress and inflammation. With the expanded use of marginal allografts more susceptible to IRI, the incidence of EAD may be increasing. This necessitates an in-depth understanding of the innate mole...
Source: PLoS One - March 28, 2024 Category: Biomedical Science Authors: Elizabeth A. Wilson Source Type: research

Observational Retrospective Study in Patients Treated with Galcanezumab as Preventive Treatment for Migraine: The ORYGAM Study
ConclusionsIn real clinical practice, galcanezumab is an effective treatment and has a high persistence in patients with migraine, mostly chronic and with multiple use of previous preventive treatments. (Source: Pain and Therapy)
Source: Pain and Therapy - March 28, 2024 Category: Anesthesiology Source Type: research

Selected 2023 Highlights in Congenital Cardiac Anesthesia
This article reviews the highlights of pertinent literature of interest to the congenital cardiac anesthesiologist published in 2023. Following a search of the United States National Library of Medicine PubMed database, several topics emerged where significant contributions were made in 2023. The authors of this manuscript considered the following topics noteworthy to be included in this review: Advancements in percutaneous mechanical support in children with CHD, children with pulmonary hypertension undergoing surgery for congenital heart disease (CHD), Dexmedetomidine in pediatric cardiac surgery, and recommendations for...
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 28, 2024 Category: Anesthesiology Authors: Ingrid Moreno-Duarte, Rishi Bharat Parikh, Joanna Paquin, Jochen Steppan, James P. Spaeth, Viviane G. Nasr, Alexander J.C. Mittnacht, Emad B. Mossad Tags: Special Article Source Type: research

2024 Guidelines for Performing a Comprehensive Pediatric Transthoracic Echocardiogram: Recommendations From the American Society of Echocardiography
Transthoracic echocardiography (TTE) has become the most utilized imaging modality for diagnosis and management of children and adults with congenital heart disease (CHD). It was not always this way. The history of echocardiography in pediatrics is interesting in that it was only in 1959 that Effert et al. first reported echocardiographic images of congenital heart defects, but the technology at the time could not consistently identify anatomical variations. 1, 2 It was another decade before echocardiography machines improved and normal neonatal and infant echocardiography images were able to be documented and expand the f...
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 28, 2024 Category: Anesthesiology Authors: Nicholas Houska, Megan Albertz, Benjamin Frank, Richard J. Ing Tags: Editorial Source Type: research

Severe back labor pain masks a scald caused by shower hydrotherapy – a case report
Hydrotherapy is one of the non-pharmacological modalities used for labor analgesia and is available as either immersion (tub) or shower hydrotherapy.1,2 The hydrokinetic and thermal effects of warm water are believed to promote muscle relaxation and local vasodilation, while stimulating the release of endorphins.3 By activating cutaneous thermo-receptors and mechano-receptors, hydrotherapy may block upward transmission of afferent labor pain fibers at the spinal cord, thereby altering labor pain perception. (Source: International Journal of Obstetric Anesthesia)
Source: International Journal of Obstetric Anesthesia - March 28, 2024 Category: Anesthesiology Authors: P.J. Angle, V Ashok, G Liu, M Trenholm, J Montbriand Tags: Case Report Source Type: research

Effects of dexmedetomidine on postoperative pain and early cognitive impairment in older male patients undergoing laparoscopic cholecystectomy
Exp Ther Med. 2024 Mar 8;27(5):189. doi: 10.3892/etm.2024.12477. eCollection 2024 May.ABSTRACTThe primary aim of the present study was to investigate the effect of dexmedetomidine (DEX) on postoperative pain and early cognitive impairment in old male patients, who underwent laparoscopic cholecystectomy (LC). A total of 97 old patients, subjected to LC at the 980 Hospital of the Joint Service Support Force of the People's Liberation Army of China, were randomly divided into two groups, namely the DEX and normal saline groups. Patients in the DEX group received an intravenous infusion of 0.8 µg/kg DEX within 10 min followin...
Source: Experimental and Therapeutic Medicine - March 27, 2024 Category: General Medicine Authors: Yanlong Fu Qiang Wei Zhenliang Wang Qingtao Zhao Wenxin Shi Source Type: research

No replication of direct neuronal activity-related (DIANA) fMRI in anesthetized mice
Sci Adv. 2024 Mar 29;10(13):eadl0999. doi: 10.1126/sciadv.adl0999. Epub 2024 Mar 27.ABSTRACTDirect imaging of neuronal activity (DIANA) by functional magnetic resonance imaging (fMRI) could be a revolutionary approach for advancing systems neuroscience research. To independently replicate this observation, we performed fMRI experiments in anesthetized mice. The blood oxygenation level-dependent (BOLD) response to whisker stimulation was reliably detected in the primary barrel cortex before and after DIANA experiments; however, no DIANA-like fMRI peak was observed in individual animals' data with the 50 to 300 trials. Exten...
Source: Adv Data - March 27, 2024 Category: Epidemiology Authors: Sang-Han Choi Geun Ho Im Sangcheon Choi Xin Yu Peter A Bandettini Ravi S Menon Seong-Gi Kim Source Type: research

A different interpretation of the DIANA fMRI signal
Sci Adv. 2024 Mar 29;10(13):eadl2034. doi: 10.1126/sciadv.adl2034. Epub 2024 Mar 27.ABSTRACTDirect detection of neural activity by functional magnetic resonance imaging (fMRI) has been a longstanding goal in neuroscience. A recent study argued that it is possible to detect neuroelectrical potentials using a specialized fMRI scanning approach the authors termed "direct imaging of neuronal activity" (DIANA). We implemented DIANA in anesthetized rats and measured responses to somatosensory stimulation, reproducing core findings of the original study. We show, however, that neural activity is neither sufficient nor necessary t...
Source: Adv Data - March 27, 2024 Category: Epidemiology Authors: Valerie Doan Phi Van Sajal Sen Alan Jasanoff Source Type: research

Robotic vs. laparoscopic distal gastrectomy for gastric cancer: A propensity score-matched retrospective comparative study at a single institution
CONCLUSIONS: Although a single-center, small comparative study, the results showed that the robotic surgery group was not inferior to the laparoscopic group in feasibility and safety. Moreover, robotic surgery enables harvesting a higher number of lymph nodes, which may be more advantageous than laparoscopic surgery. This study also showed that as the surgeon gains experience with robotic surgery, its operative time becomes significantly shorter.PMID:38538396 | DOI:10.1016/j.asjsur.2024.03.086 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 27, 2024 Category: Surgery Authors: Masaki Kitazono Makoto Fujita Shuichiro Uchiyama Mayumi Eguchi Naotaka Ikeda Source Type: research

The movement of syringes and medication during anesthesiology delivery: An observational study in laparoscopic surgeries
Appl Ergon. 2024 Mar 26;118:104263. doi: 10.1016/j.apergo.2024.104263. Online ahead of print.ABSTRACTThe movements of syringes and medications during an anesthetic case have yet to be systematically documented. We examine how syringes and medication move through the anesthesia work area during a case. We conducted a video-based observational study of 14 laparoscopic surgeries. We defined 'syringe events' as when syringe was picked up and moved. Medications were administered to the patient in only 48 (23.6%) of the 203 medication or syringe events. On average, 14.5 syringe movements occurred in each case. We estimate approx...
Source: Applied Ergonomics - March 27, 2024 Category: Occupational Health Authors: David M Neyens Rong Yin James H Abernathy Catherine Tobin Candace Jaruzel Ken Catchpole Source Type: research

An Individual Barrier Enclosure Actively Removing Aerosols for Airborne Isolation: A Vacuum Tent
CONCLUSIONS: The vacuum tent effectively minimized aerosol dispersion. Its continuous suction system set at a high suction flow was crucial to avoid the spread of aerosol particles and CO2 rebreathing.PMID:38538026 | DOI:10.4187/respcare.11094 (Source: Respiratory Care)
Source: Respiratory Care - March 27, 2024 Category: Respiratory Medicine Authors: Fernando N Vieira Veronique Masy Ryan J LaRue Scott E Laengert Charles F De Lannoy Antenor Rodrigues Michael C Sklar Nick Lo Andrew Petrosoniak Joao Rezende-Neto Laurent J Brochard Source Type: research

Pre-incisional local infiltration with levobupivacaine in laparoscopic cholecystectomy: a randomized and clinical trial
CONCLUSIONS: Levobupivacaine infiltration is safe and effective in reducing POP, although this does not lead to a shorter hospital stay and does not influence HRQoL, return to work, or overall patient satisfaction.PMID:38537241 | DOI:10.24875/CIRU.230000221 (Source: Cirugia y Cirujanos)
Source: Cirugia y Cirujanos - March 27, 2024 Category: Surgery Authors: Jorge Herrador-Benito Javier P áramo-Zunzunegui Gil Rodr íguez-Caravaca Manuel Dur án-Poveda Source Type: research

Comment on "Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial"
Korean J Anesthesiol. 2024 Mar 27. doi: 10.4097/kja.24070. Online ahead of print.NO ABSTRACTPMID:38533590 | DOI:10.4097/kja.24070 (Source: Korean Journal of Anesthesiology)
Source: Korean Journal of Anesthesiology - March 27, 2024 Category: Anesthesiology Authors: Anju Gupta Nitin Choudhary Nishkarsh Gupta Source Type: research

Neuro-protective Effect of Acetyl-11-keto- β-boswellic Acid in a Rat Model of Scopolamine-induced Cholinergic Dysfunction
CONCLUSION: The results suggested the effectiveness of AKBA in preventing learning and memory dysfunction induced by scopolamine. Accordingly, these protective effects might be produced by modulating BDNF, cholinergic system function, oxidative stress, and apoptotic markers.PMID:38532323 | DOI:10.2174/0113816128269289231226115446 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - March 27, 2024 Category: Drugs & Pharmacology Authors: Amir Hossein Assaran Mahmoud Hosseini Matin Shirazinia Mohammad Hosein Eshaghi Ghalibaf Farimah Beheshti Leila Mobasheri Farshad Mirzavi Arezoo Rajabian Source Type: research