Standard Therapy in Cardiac Amyloidosis
This study aims to highlight the most compelling issues concerning patients ’ clinical management with HF and CA. (Source: Heart Failure Clinics)
Source: Heart Failure Clinics - April 6, 2024 Category: Cardiology Authors: Annamaria Del Franco, Giulia Biagioni, Carlotta Mazzoni, Alessia Argir ò, Mattia Zampieri, Francesco Cappelli Source Type: research
Chronic underlying gastrointestinal amyloidosis was revealed by cardiac echography: a case report from Syria
CONCLUSION: This case reminds us to consider amyloidosis as a possible underlying cause for unexplained gastrointestinal symptoms such as diarrhoea, especially in bad economic situations where the diagnosis of rare diseases may be delayed.PMID:38576978 | PMC:PMC10990300 | DOI:10.1097/MS9.0000000000001901 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Ali Asaad Yahia Ranjous Zein Aldeen Hassan Nazir Alahmad Lama Ghanimeh Ayman Ali Source Type: research
Clinically Undiagnosed Diseases in Autopsies: Frequency and Risk Factors
CONCLUSIONS.—: Autopsy is a useful investigation for the detection of clinically undiagnosed entities. In our cohort, cardiac amyloidosis showed the highest number of underlying risk factors, but was clinically underdiagnosed. Our findings underline the necessity of improved clinical detection of cardiac amyloidosis, especially in light of emerging therapeutic options. Moreover, we characterize the most common entities prone to clinical underdiagnosis.PMID:38576236 | DOI:10.5858/arpa.2023-0429-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - April 5, 2024 Category: Laboratory Medicine Authors: Umberto Maccio Christoph Andreas Meier Michael Reinehr Frank Ruschitzka Reto Sch üpbach Holger Moch Zsuzsanna Varga Source Type: research
Chronic underlying gastrointestinal amyloidosis was revealed by cardiac echography: a case report from Syria
CONCLUSION: This case reminds us to consider amyloidosis as a possible underlying cause for unexplained gastrointestinal symptoms such as diarrhoea, especially in bad economic situations where the diagnosis of rare diseases may be delayed.PMID:38576978 | PMC:PMC10990300 | DOI:10.1097/MS9.0000000000001901 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Ali Asaad Yahia Ranjous Zein Aldeen Hassan Nazir Alahmad Lama Ghanimeh Ayman Ali Source Type: research
Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry
CONCLUSION: During registry set-up, a more comprehensive work-up of our patients suffering mainly from light-chain amyloidosis and transthyretin amyloidosis was implemented. Survival rates were remarkably high and similar between light-chain amyloidosis and transthyretin amyloidosis, a finding which was noted in similar historic registries of international centres. However, further studies are needed to depict morbidity and mortality as the amyloidosis landscape is changing rapidly.PMID:38579306 | DOI:10.57187/s.3485 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Sofie Brouwers Raphael Heimgartner Natallia Laptseva Adriano Aguzzi Niklas F Ehl Thomas Fehr Felicitas Hitz Hans H Jung Joel K älin Markus G Manz Beat M üllhaupt Frank Ruschitzka Harald Seeger Georg Stussi Markus Zweier Andreas J Flammer Bernhard Gerber Source Type: research
Clinically Undiagnosed Diseases in Autopsies: Frequency and Risk Factors
CONCLUSIONS.—: Autopsy is a useful investigation for the detection of clinically undiagnosed entities. In our cohort, cardiac amyloidosis showed the highest number of underlying risk factors, but was clinically underdiagnosed. Our findings underline the necessity of improved clinical detection of cardiac amyloidosis, especially in light of emerging therapeutic options. Moreover, we characterize the most common entities prone to clinical underdiagnosis.PMID:38576236 | DOI:10.5858/arpa.2023-0429-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - April 5, 2024 Category: Laboratory Medicine Authors: Umberto Maccio Christoph Andreas Meier Michael Reinehr Frank Ruschitzka Reto Sch üpbach Holger Moch Zsuzsanna Varga Source Type: research
Chronic underlying gastrointestinal amyloidosis was revealed by cardiac echography: a case report from Syria
CONCLUSION: This case reminds us to consider amyloidosis as a possible underlying cause for unexplained gastrointestinal symptoms such as diarrhoea, especially in bad economic situations where the diagnosis of rare diseases may be delayed.PMID:38576978 | PMC:PMC10990300 | DOI:10.1097/MS9.0000000000001901 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Ali Asaad Yahia Ranjous Zein Aldeen Hassan Nazir Alahmad Lama Ghanimeh Ayman Ali Source Type: research
Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry
CONCLUSION: During registry set-up, a more comprehensive work-up of our patients suffering mainly from light-chain amyloidosis and transthyretin amyloidosis was implemented. Survival rates were remarkably high and similar between light-chain amyloidosis and transthyretin amyloidosis, a finding which was noted in similar historic registries of international centres. However, further studies are needed to depict morbidity and mortality as the amyloidosis landscape is changing rapidly.PMID:38579306 | DOI:10.57187/s.3485 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Sofie Brouwers Raphael Heimgartner Natallia Laptseva Adriano Aguzzi Niklas F Ehl Thomas Fehr Felicitas Hitz Hans H Jung Joel K älin Markus G Manz Beat M üllhaupt Frank Ruschitzka Harald Seeger Georg Stussi Markus Zweier Andreas J Flammer Bernhard Gerber Source Type: research
Clinically Undiagnosed Diseases in Autopsies: Frequency and Risk Factors
CONCLUSIONS.—: Autopsy is a useful investigation for the detection of clinically undiagnosed entities. In our cohort, cardiac amyloidosis showed the highest number of underlying risk factors, but was clinically underdiagnosed. Our findings underline the necessity of improved clinical detection of cardiac amyloidosis, especially in light of emerging therapeutic options. Moreover, we characterize the most common entities prone to clinical underdiagnosis.PMID:38576236 | DOI:10.5858/arpa.2023-0429-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - April 5, 2024 Category: Laboratory Medicine Authors: Umberto Maccio Christoph Andreas Meier Michael Reinehr Frank Ruschitzka Reto Sch üpbach Holger Moch Zsuzsanna Varga Source Type: research
Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry
CONCLUSION: During registry set-up, a more comprehensive work-up of our patients suffering mainly from light-chain amyloidosis and transthyretin amyloidosis was implemented. Survival rates were remarkably high and similar between light-chain amyloidosis and transthyretin amyloidosis, a finding which was noted in similar historic registries of international centres. However, further studies are needed to depict morbidity and mortality as the amyloidosis landscape is changing rapidly.PMID:38579306 | DOI:10.57187/s.3485 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Sofie Brouwers Raphael Heimgartner Natallia Laptseva Adriano Aguzzi Niklas F Ehl Thomas Fehr Felicitas Hitz Hans H Jung Joel K älin Markus G Manz Beat M üllhaupt Frank Ruschitzka Harald Seeger Georg Stussi Markus Zweier Andreas J Flammer Bernhard Gerber Source Type: research
Preclinical evaluation of Tc-99m p5+14 peptide for SPECT detection of cardiac amyloidosis
Conclusion99mTc-p5+14 was prepared in minutes in>20 mCi doses with good performance in preclinical studies making it suitable for clinical SPECT/CT imaging of cardiac amyloidosis. (Source: PLoS One)
Source: PLoS One - April 5, 2024 Category: Biomedical Science Authors: Stephen J. Kennel Source Type: research
Catheter ablation of atrial arrhythmias in cardiac amyloidosis: Impact on heart failure and mortality
ConclusionThis study demonstrates moderate long-term efficacy of SR maintenance with catheter ablation for AA in patients with CA. Improvements in clinical and biological status with positive trends in HF mortality are observed if SR can be maintained. (Source: PLoS One)
Source: PLoS One - April 5, 2024 Category: Biomedical Science Authors: Philippe Maury Source Type: research
