Genes for 'Liking' Amphetamine Lower Schizophrenia, ADHD RiskGenes for 'Liking' Amphetamine Lower Schizophrenia, ADHD Risk
Genetic variants that increase sensitivity to the euphoric effects of amphetamine may also protect against the development of schizophrenia or ADHD. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - April 11, 2014 Category: Psychiatry Tags: Psychiatry News Source Type: news

Figures for deaths from legal highs 'inflated', say former drugs advisers
Prof David Nutt and Dr Les King say UK data includes deaths caused by substances that are not legal highsFigures for the number of deaths caused by legal highs are misleading and hampering attempts to formulate a sensible drugs policy in the UK, former government advisers warn on Friday.Prof David Nutt and Dr Les King say that the number of deaths, recorded as having risen 600% between 2009 and 2012, have been inflated by the inclusion of fatalities linked to substances that do not meet the definition of legal highs, or "new psychoactive substances".In a letter published in the Lancet, the scientists from the Independent S...
Source: Guardian Unlimited Science - March 14, 2014 Category: Science Authors: Haroon Siddique Tags: theguardian.com Science policy News Society Drugs David Nutt UK news Source Type: news

Amphetamine abuse in Sweden: subject demographics, changes in blood concentrations over time, and the types of coingested substances - Jones AW, Holmgren A.
Amphetamine is a major drug of abuse in Sweden and in the other Nordic countries. The demographics of amphetamine abusers in Sweden and the concentrations of this stimulant in blood are reported for 10 years of forensic blood samples (2001-2010). Using a f... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 6, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Persistent amphetamine consumption by truck drivers in São Paulo State, Brazil, despite the ban on production, prescription, and use - de Oliveira LG, Endo LG, Sinagawa DM, Yonamine M, Muñoz DR, Leyton V.
This study analyzes persistent amphetamine ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 5, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Sriracha, Zohydro, and more: tox on the web
  http://www.youtube.com/watch?v=U2DJN0gnuI8 The science of Sriracha: The American Chemical Society has a must-see video on Sriracha hot sauce — it goes well with everything — including disquisitions about the origin of the Scoville scale and the physiology of capsaicinoids. (HT @ToxTalk) Early ads for sedatives: The Milwaukee Journal-Sentinel — which is doing some of the best reporting in the country on drugs and the pharmaceutical industry — has a great collection of medical journal ads for tranquilizers from the 1950s and 60s.  This post accompanies their story on the deadly interaction between sedat...
Source: The Poison Review - March 5, 2014 Category: Toxicology Authors: Leon Tags: Medical amphetamine drug screen capsaicin did she kill him Florence Maybrick gravel Kate Coloquhoun PVP pyrrolidinopentiophenone scoville scale sedative sriracha tox on the web tranquilizer advertisement zohydro Source Type: news

Analysis of new classes of recreational drugs in sewage: Synthetic cannabinoids and amphetamine-like substances - Reid MJ, Derry L, Thomas KV.
The analysis of sewage for the residues of commonly used illicit drugs has successfully been applied as a suitable approach for estimating community illicit drug use. The drug market is increasingly dynamic with new substances continually being marketed fo... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 3, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

The global epidemiology and burden of psychostimulant dependence: Findings from the Global Burden of Disease Study 2010 - Degenhardt L, Baxter AJ, Lee YY, Hall W, Sara GE, Johns N, Flaxman A, Whiteford HA, Vos T.
AIMS: To estimate the global prevalence of cocaine and amphetamine dependence and the burden of disease attributable to these disorders. METHODS: An epidemiological model was developed using DisMod-MR, a Bayesian meta-regression tool, using epidemiological... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 28, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Why is cocaine adulterated with an animal dewormer? Mystery solved?
3.5 out of 5 stars Aminorex, a metabolic of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. Hofmaier T et al. Neurochem Int 2013 Dec 1 [Epub ahead of print] Abstract During the last decade, many shipments of cocaine seized by U.S. drug authorities have been found to be adulterated with levamisole, a veterinary anti-worming medicine. The drug in the past has been used to treat various medical conditions in humans, but was withdrawn from the market because of significant  adverse reactions. Levamisole has also been associated with the occurrence of agranulocytosis and dermal ...
Source: The Poison Review - February 21, 2014 Category: Toxicology Authors: Leon Tags: Medical adulterated aminorex cocaine levamisole Source Type: news

Acute poisoning with weight-loss dietary supplement falsely suggesting the use of amphetamine - Łukasik-Głebocka M, Sommerfeld K, Tężyk A, Zielińska-Psuja B.
We report a case of abuse of weight-loss dietary supplement in 27-year-old man, with characteristic for amphetamine sympathomimetic symptoms and positive analysis of this drug in the urine by immunoassay method (FPIA; Axsym, Abbott). However pos... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 15, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Are energy drinks linked to drug use?
Conclusion This cross-sectional survey has assessed the self-reported use of energy drinks and soft drinks among a large nationally representative sample of almost 22,000 US secondary school students. It found that roughly a third of adolescents aged 13 to 18 years reported drinking energy drinks daily, and just under half reported drinking regular soft drinks daily. The use of energy drinks and soft drinks was slightly higher among those in the 8th grade (13 to 14 years) than the 10th or 12th grades. The researchers found a general trend that increased use of energy drinks was associated with increased use of substances...
Source: NHS News Feed - February 7, 2014 Category: Consumer Health News Tags: Pregnancy/child Food/diet Source Type: news

amphetamine and dextroamphetamine, Adderall, Adderall XR
Title: amphetamine and dextroamphetamine, Adderall, Adderall XRCategory: MedicationsCreated: 4/17/1999 8:28:00 PMLast Editorial Review: 2/4/2014 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - February 4, 2014 Category: Drugs & Pharmacology Source Type: news

Beware of Being "Right"
Much of the emotional suffering in the world comes from the substitution of power for value. The curse of our times is that so many people have developed the habit of seeking to feel temporarily more powerful when they feel devalued.read more (Source: Psychology Today Relationships Center)
Source: Psychology Today Relationships Center - January 15, 2014 Category: Psychiatry & Psychology Authors: Steven Stosny, Ph.D. Tags: Relationships Self-Help abuse amphetamine anger constellation contempt cup of coffee curse disrespect egos electronic age emotional state emotions error rate habit humane values illusion illusion of certainty illusion Source Type: news

Make the diagnosis: 16-month-old child with irritability
3 out of 5 stars A 16-Month-Old Girl with Irritability After Ingesting White Pills. Jones MA et al. Pediatr Emerg Care 2014 Jan;30:69-71. Reference – no abstract available This short diagnostic puzzle was presented as part of Pediatric Emergency Care‘s “Pick Your Poison” series. A 16-month-old girl is brought to the emergency department with irritability, diaphoresis, tachycardia (152 bpm, resistant to fluids), hypokalemia (3.7 mmol/L) and an anion-gap metabolic acidosis (gap = 24). The father reports that the child was found ingesting “white pills” contained in her grandmother’s...
Source: The Poison Review - January 9, 2014 Category: Toxicology Authors: Leon Tags: Medical caffeine toxicity diet pills dimethylamylamine dmaa pediatric poisoning sympathomimetic toxidrome Source Type: news

Illicit drug residues in Swedish sewage water
Chemists at Umea University have been able to trace narcotics substances and prescription drugs in measurements of wastewater from 33 Swedish sewage treatment plants. Cocaine, amphetamine, and methamphetamine, in measurable concentrations, were found in a total of half of the locations.When a person consumes a drug it is excreted through the digestive system, either unchanged or as metabolites through the body and ends up in the wastewater. Through taking a sample of water in treatment plants and measuring the levels of drugs can provide a snapshot of the drug usage in a particular city. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 24, 2013 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Evaluation of the effects of anti-motion sickness drugs on subjective sleepiness and cognitive performance of healthy males - Weerts A, Pattyn N, Van de Heyning P, Wuyts F.
This study aimed to investigate the clinical and cognitive side effects of baclofen (10 mg), meclizine (50 mg), dimenhydrinate (40 mg) plus cinnarizine (20 mg) and promethazine (25 mg) plus d-amphetamine (5 mg). The study had a double-blind, placebo contro... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - December 21, 2013 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news