Methamphetamine/amphetamine abuse and risk of Parkinson's disease in Utah: a population-based assessment - Curtin K, Fleckenstein AE, Robison RJ, Crookston MJ, Smith KR, Hanson GR.
BACKGROUND: Despite widespread use of methamphetamine and other amphetamine-type stimulants (METH/AMPH), little is known about the long-term medical consequences of METH/AMPH abuse and dependence. Preclinical neurotoxicity findings raise public health conc... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - December 14, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Patient complains of bugs on her skin — could it be tox?
2.5 out of 5 stars
Case 37-2014: A 35-Year-Old woman with Suspected Mite Infestation. Beach SR et al. N Engl J Med 2014 Nov 27;371:2115-2123.
No abstract available
This case — part of the Journal‘s “Case Records of the Massachusetts General Hospital” series — describes a 35-year-old woman had presented to the emergency department complaining of a parasitic skin infection:
“During the 10 days before this presentation, she reported seeing white ‘granular balls,’ which she thought were mites or larvae, emerging from and crawling on her skin, sheets, and clothing and in her feces, apar...
Source: The Poison Review - December 13, 2014 Category: Toxicology Authors: Leon Tags: Medical amphetamine psychosis delusional parasitosis formication Source Type: news
Snorting bupropion
2.5 out of 5 stars
An 11-year review of bupropion insufflation exposures in adults reported to the California Poison Control System. Lewis JC et al. Clin Toxicol 2014 Nov;52:969-972.
Abstract
The abuse of bupropion by pulverizing and snorting the medication has been described at least as far back as 2002. Bupropion inhibits re-uptake of dopamine and norepinephrine, but apparently has little or no effect on serotonin. It is abused for its psychotropic effects that resemble those of amphetamine and cocaine..
A hallmark of overdose with sustained-release or extended-release bupropion formulations is delayed onset of seizures...
Source: The Poison Review - November 13, 2014 Category: Toxicology Authors: Leon Tags: Medical burpropion delayed seizures overdose toxicity Wellbutrin Zyban Source Type: news
TPR Podcast Episode #6: I’m tripping and I can’t get down
TPR Podcast Episode 6: I’ve Tripped and I Can’t Get Down
Written by Theresa Kim, MD
Outline
1) Synthetic cathinones
2) Piperazine compounds
3) Gamma-hydroxybutyric acid (GHB)
4) 25C-NBOMe
This month’s podcast was inspired by the New York Times article “A Year After Drug Deaths, the Electric Zoo Music Festival Tries Again” which covered designer drug related deaths associated with summer music festivals
Synthetic Cathinones
Derivatives of the Catha edulis (khat) plant’s psychoactive alkaloid (cathinone)
o examples: mephedrone, methedrone, MD...
Source: The Poison Review - October 7, 2014 Category: Toxicology Authors: LeonThe Poison Review Tags: Podcast Source Type: news
Use trajectories of amphetamine-type stimulants (ATS) in Shanghai, China - Du J, Sun H, Huang D, Jiang H, Zhong N, Xu D, Zhao Y, Lin S, Wang W, Du Z, Zhao M, Hser YI.
This study explored long-term patterns... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 8, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Acute methoxetamine and amphetamine poisoning with fatal outcome - A case report - Wiergowski M, Anand JS, Krzyzanowski M, Jankowski Z.
Methoxetamine (MXE) is a psychoactive substance distributed mostly via the Internet and is not liable to legal regulation in Poland. MXE has a toxicity profile similar to that of ketamine but longer-lasting effects. The paper describes a case of acute pois... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 31, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
[Editors' Choice] Synaptic transmission on speed
Amphetamine stimulates neuronal activity by decreasing the clearance of an excitatory neurotransmitter from the synaptic space. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 30, 2014 Category: Science Authors: Nancy Gough (mailto:ngough at aaas.org) Source Type: news
Many Teenagers Unaware That Adderall Is an Amphetamine
Discordant responses common; 28.7 percent who reported Adderall use reported no amphetamine use (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - July 14, 2014 Category: Psychiatry Tags: Family Medicine, Nursing, Pediatrics, Pharmacy, Psychiatry, Journal, Source Type: news
Retrospective review of nutmeg toxicity
2.5 out of 5 stars
Nutmeg Poisonings: A Retrospective Review of 10 Years Experience from the Illinois Poison Center: 2001-2011. Ehrenpreis JE et al. J Med Toxicol 2014;10:148-151.
Abstract
Just when you thought it was safe to go back to the eggnog bowl . . .
Nutmeg is the seed of the aromatic evergreen Myristica fragrans. It contains a number of volatile oils, some of which may be metabolized to monoamine oxidase inhibitors or amphetamine-like substances.
Manifestations of nutmeg toxicity are quite similar to those of the anticholinergic syndrome, including dry mouth, flushing, tachycardia, tremor, urinary retention and...
Source: The Poison Review - July 10, 2014 Category: Toxicology Authors: Leon Tags: Medical anticholinergic syndrome myristica fragrans nutmeg Source Type: news
Neuropsychological functioning among chronic khat users in Jazan Region, Saudi Arabia - Ismail AA, El Sanosy RM, Rohlman DS, El-Setouhy M.
BACKGROUND: Khat chewing effects in the central nervous system are attributed to cathinone and cathine, which are structurally related to amphetamine. However, studies on neuropsychological problems arising from khat use in humans are not extensive and hav... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - June 28, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Shire agrees to test its ADHD drug in preschool children
LONDON (Reuters) - London-listed drugmaker Shire PLC said it had agreed to a request from the U.S. regulator to test the use of its amphetamine-based drug Vyvanse in preschool children aged four and five with hyperactivity. (Source: Reuters: Health)
Source: Reuters: Health - June 12, 2014 Category: Consumer Health News Tags: healthNews Source Type: news
Could a compound found in cannabis treat epilepsy?
Conclusion
The summary of evidence on the potential use of the active ingredients in cannabis to reduce epileptic seizures highlights one thing: the evidence does not point to any clear answers.
This summary also has a significant risk of bias because it did not employ systematic methods to identify all the relevant information on the topic.
Nonetheless, it reached cautious conclusions, highlighting the need for more robust information from randomised controlled trials (RCT) to inform the debate.
Some of the media reports were less cautious, but still reported the unclear picture around whether cannabis could be used me...
Source: NHS News Feed - May 23, 2014 Category: Consumer Health News Tags: Medication Neurology Source Type: news
Another Treatment for ADHD?
Drugs are only one answer when treating ADHD ...read more (Source: Psychology Today Parenting Center)
Source: Psychology Today Parenting Center - May 20, 2014 Category: Psychiatry & Psychology Authors: Naveed Saleh, M.D., M.S. Tags: Child Development Integrative Medicine Parenting Psychiatry ADD adderall aderall ADHD amphetamine behavioral therapy OMT osteopathic manipulative treatment stimulants Source Type: news
Can exercise help reduce methamphetamine use?
Exercise may help reduce methamphetamine use, researchers have concluded after a recent study. The abuse of amphetamine type psychomotor stimulants remains a critical legal and public health problem in the US. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 27, 2014 Category: Science Source Type: news
