Mixed-amphetamine salts expectancies among college students: is stimulant induced cognitive enhancement a placebo effect? - Cropsey KL, Schiavon S, Hendricks PS, Froelich M, Lentowicz I, Fargason R.
INTRODUCTION: Non-medical use of prescription stimulants for cognitive enhancement in college students is increasing, despite evidence showing little benefit in non-clinical populations. The balanced placebo design (BPD) was used to independently evaluate ... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Morning administration of oral methamphetamine dose-dependently disrupts nighttime sleep in recreational stimulant users - Herrmann ES, Johnson PS, Bruner NR, Vandrey R, Johnson MW.
INTRODUCTION: Use of amphetamine-type stimulants (e.g., methamphetamine) is associated with acute sleep disruptions. No prior reports have characterized the acute effects of methamphetamine on sleep using polysomnography, the gold standard for objective sl... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Discrimination between drug abuse and medical therapy: case report of a tranylcypromine overdose-related fatality - Akhgari M, Jokar F, Etemadi-Aleagha A, Ghasemi A.
Tranylcypromine is an effective antidepressant from the class of monoamine oxidase inhibitors and is structurally related to amphetamine. However, reports differ regarding the potential metabolism of tranylcypromine to amphetamine and methamphetamine withi... (Source: SafetyLit)
Source: SafetyLit - July 14, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Study: Most ADHD medications aren't associated with risk of irritability
Irritability is common across psychiatric diagnoses, but is especially common in children with ADHD. Some common ADHD medications are purported to increase irritability, leading doctors and families to avoid them, even though medication is a highly effective treatment. However, a Yale study found that only amphetamine-derived medications were associated with an increase in irritability. Methylphenidates were not. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 13, 2017 Category: Universities & Medical Training Source Type: news

Mydayis (Mixed Salts of a Single-entity Amphetamine Product Capsules) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 28, 2017 Category: Drugs & Pharmacology Source Type: news

The addition of amphetamine to potentially sedating medication regimens: an exploratory investigation of the impact upon reaction time and sustained attention - Price JW.
OBJECTIVES: The addition of amphetamine to a sedating medication may reduce sedation but does it augment reaction time and sustained attention for workers? The purpose of this exploratory study was gain insight into between group differences that would ass... (Source: SafetyLit)
Source: SafetyLit - June 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Shire receives FDA approval for Mydayis to treat attention deficit hyperactivity disorder
Biotechnology company Shire has received the US Food and Drug Administration (FDA) approval for Mydayis (mixed salts of a single-entity amphetamine product) for the treatment of attention deficit hyperactivity disorder (ADHD). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - June 21, 2017 Category: Pharmaceuticals Source Type: news

Another extended-release ADHD drug wins FDA nod
Days after Neos Therapeutics (NSDQ:NEOS) nabbed U.S. regulatory approval for its controlled-release formulation of methylphenidate, Shire (NSDQ:SHPG) said it won a nod from the FDA for its long-acting ADHD drug. The drug, Mydayis, is made up of the same active ingredient in Shire’s ADHD treatment Adderall XR – amphetamine – but it is designed to last up to 16 hours. Adderall XR is formulated to control symptoms in patients for up to 12 hours. Get the full story at our sister site, Drug Delivery Business News. The post Another extended-release ADHD drug wins FDA nod appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - June 21, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Food & Drug Administration (FDA) Neurological Pharmaceuticals Regulatory/Compliance Wall Street Beat neostherapeutics Shire Plc. Source Type: news

FDA Clears Long-Acting ADHD Drug Mydayis FDA Clears Long-Acting ADHD Drug Mydayis
Mydayis (mixed salts of amphetamine) is formulated to last up to 16 hours and is approved for adults and children aged 13 years and older.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 21, 2017 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news

FDA Approves Mydayis (mixed salts of a single-entity amphetamine product) – A New Once-Daily Option for ADHD
Lexington, Mass., USA – June 20, 2017 – Shire plc (LSE: SHP, NASDAQ: SHPG) announced today that the U.S. Food and Drug Administration (FDA) has approved Mydayis (mixed salts of a single-entity amphetamine product), a once-daily treatment... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Dyanavel XR (Amphetamine Extended-release Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 25, 2017 Category: Drugs & Pharmacology Source Type: news

Medico-legal assessment of methamphetamine and amphetamine serum concentrations-what can we learn from survived intoxications? - Weber M, Lessig R, Richter C, Ritter AP, Wei ß I.
Medico-legal experts are increasingly enlisted to assess the methamphetamine and amphetamine serum concentrations after a criminal offense. However, since criminal users rarely provide useful information to medico-legal experts regarding the substances abu... (Source: SafetyLit)
Source: SafetyLit - May 19, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The forensic implications of amphetamine intoxication in cases of inflicted blunt craniocerebral trauma - Byard RW, Donkin J, Vink R.
The effects of D-amphetamine on outcome after blunt craniocerebral trauma are characterized and the potential legal implications discussed. Traumatic brain injury (TBI) was induced under general anesthesia in adult, male Sprague Dawley rats using the impac... (Source: SafetyLit)
Source: SafetyLit - April 11, 2017 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

San Diego Debuts Mouth Swabs To Detect Drivers High On Pot
A major concern of police about state laws legalizing marijuana has been how to detect when motorists may be driving under the influence of pot — or other drugs. Now San Diego police are joining a growing number of cities relying on mouth swabs for chemical tests to detect drugs in drivers. The swabs and two portable testing machines hit the field Friday night in San Diego, reported CBS-8 TV. It’s the second city in the state after Los Angeles to use the new detection method. The machines test for the presence of marijuana and six other drugs: cocaine, methamphetamine, amphetamine, methadone, opiates and benzod...
Source: Science - The Huffington Post - March 19, 2017 Category: Science Source Type: news

Pharmacological and non-pharmacological treatment of adults with ADHD: a meta-review
In conclusion, while available evidence addressed mainly the efficacy and tolerability of psychostimulants and non-psychostimulants for ADHD core symptoms in the short term, we still need further empirical support for the non-pharmacological and multimodal treatments. A comprehensive evidence-informed hierarchy of ADHD drugs based on their efficacy and tolerability is not yet available but it should be the next research priority in the field. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 16, 2017 Category: Consumer Health News Source Type: news