What to D.O.: Opioids Are Out, Amitriptyline Is In, Despite Failings
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - January 1, 2019 Category: Emergency Medicine Tags: What to D.O. Source Type: news
Amitriptyline'Still an Option' for Back Pain Amitriptyline'Still an Option' for Back Pain
A randomized trial of the low-dose antidepressant for chronic low back pain showed no significant improvement in the primary outcome, but researchers still conclude it ' s an ' option ' on the basis of secondary measures.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 26, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Antidepressants'Worth Trying' for Back Pain (CME/CE)
(MedPage Today) -- Amitriptyline improved disability, but didn ' t significantly relieve pain (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - October 3, 2018 Category: Psychiatry Source Type: news
Could some commonly used drugs improve survival from sepsis
This assessment of media reports describes how newspaper articles have been based on early stage research which suggested that 5 drugs (including chlorpromazine, amitriptyline and topotecan) seemed effective in mice with sepsis. There has been no research in humans and has no implications currently for sepsis management (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 22, 2018 Category: Consumer Health News Source Type: news
What You Need to Know About the Newest Antidepressants
In addition to therapy, medication can be an invaluable treatment for clinical depression. It may alleviate symptoms and literally save lives. Which is why having an array of medications to choose from is vital.
Recently, in the U.S., three antidepressants were approved by the Food and Drug Administration (FDA) to treat depression: vilazodone (Viibryd) in 2011; levomilnacipran (Fetzima) in 2013; and vortioxetine (Trintellix; formerly called Brintellix, but renamed to avoid confusion with the blood-thinning medication Brilinta) in 2013.
In general, these medications are well-tolerated and effective. However, they’re no mo...
Source: Psych Central - May 21, 2018 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Depression Disorders General Medications Antidepressants Clinical Depression Fetzima Levomilnacipran Major Depression Major Depressive Disorder newest antidepressants Trintellix Viibryd Vilazodone vortioxetine Source Type: news
Some antidepressants linked to dementia risk
Scientists say doctors should consider weaning patients with depression, Parkinsons or bladder problems off anticholinergic drugsSome antidepressants and bladder medicines could be linked to dementia, according to a team of scientists who are calling for doctors to think about “de-prescribing” them where possible.Tricyclic antidepressants such as amitriptyline, which are also prescribed for pain and to help with sleeping, and one of the SSRI class, paroxetine (also known as Seroxat), are implicated by the largest ever study to look at this possible risk.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 25, 2018 Category: Science Authors: Sarah Boseley Health editor Tags: Dementia Mental health Medical research Science University of East Anglia Depression Parkinson's disease Source Type: news
21 Reviewed Antidepressants Top Placebo for Major Depression
Agomelatine, amitriptyline, escitalopram are among most effective agents in head - to - head trials (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - February 22, 2018 Category: Psychiatry Tags: Family Medicine, Gynecology, Internal Medicine, Pharmacy, Psychiatry, Journal, Source Type: news
These Antidepressants Are Most Effective, Study Says
Millions of people take antidepressants for depression. But there’s long been debate over just how effective the medications actually are. On Wednesday, a large new study provides evidence that antidepressants are more effective than placebo at treating acute depression in adults.
The study, published in the journal The Lancet, looked at the published data from 522 randomized controlled trials testing 21 different types of antidepressants. The study authors also reached out to pharmaceutical companies and study authors for additional unpublished study data. All told, the data collection included 116,477 men and women...
Source: TIME: Health - February 21, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news
What Treatment is Recommended for Common Headaches?
Discussion
Headache is pain in the scalp, forehead, orbits and temple. Facial and neck pain are usually excluded from this definition. It is a common problem with more than 6 million pediatric patients having migraine. Headaches can also have co-morbidities and more than 1 primary headache type can co-exist. The costs are high both economically and in the quality of life for the patients and families. A review of common headache types and indications for neuroimaging can be found here.
Treatment is necessarily multi-pronged. Patients should understand their diagnosis so they can understand what reasonably can be expected...
Source: PediatricEducation.org - January 15, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Mother Accused of Killing Daughter With Antidepressants Will Stand Trial
(GLENWOOD, Iowa) — A southwestern Iowa mother accused of giving her 8-year-old daughter fatal amounts of an antidepressant drug is set to stand trial in December.
Mills County court records say 34-year-old Misty Frazier, has pleaded not guilty to second-degree murder, child endangerment and giving prescription drugs to a minor without a prescription. The trial is set to begin Dec. 12 for the Glenwood resident.
Prosecutors say an autopsy shows the girl died in October of an overdose of the antidepressant amitriptyline, commonly sold under the brand name Elavil.
Glenwood is about 25 miles (40 kilometers) southeast of O...
Source: TIME.com: Top Science and Health Stories - October 3, 2017 Category: Consumer Health News Authors: Associated Press Tags: Uncategorized APW Crime onetime Source Type: news
C.O. Truxton, Inc. Issues Voluntary Nationwide Recall of Amitriptyline HCL Tablets, USP 50mg and Phenobarbital Tablets, USP 15mg, 30mg, 60mg, 100mg Due to Potential Label Mix-Up
Bellmawr, New Jersey, C.O. Truxton, Inc. is expanding their 04/21/2017 voluntary recall, as a precaution to include the following C.O. Truxton, Inc. products, registered NDC numbers and corresponding lot numbers, to the consumer/user level. C.O. Truxton has not received any complaints for the products listed below. however, due to the initial recall resulting from a label mix-up error, out of an abundance of caution, we are recalling all products that were repackaged into a Truxton Incorporated label. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 8, 2017 Category: Food Science Source Type: news
Antidepressant may enhance delivery of medication to the brain
An NIEHS rat study suggests amitriptyline temporarily inhibits the blood-brain barrier, so medications can enter the brain. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - May 2, 2017 Category: Environmental Health Source Type: news
Antidepressant may enhance drug delivery to the brain
Pairing the antidepressant amitriptyline with drugs designed to treat central nervous system diseases, enhances drug delivery to the brain by inhibiting the blood-brain barrier in rats, new research shows. The blood-brain barrier serves as a natural, protective boundary, preventing most drugs from entering the brain. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 27, 2017 Category: Science Source Type: news
Antidepressant May Enhance Drug Delivery to the Brain
New research from the National Institutes of Health found that pairing the antidepressant amitriptyline with drugs designed to treat central nervous system diseases, enhances drug delivery to the brain by inhibiting the blood-brain barrier in rats. (Source: NIEHS News)
Source: NIEHS News - April 27, 2017 Category: Environmental Health Source Type: news
Antidepressant may enhance drug delivery to the brain
(NIH/National Institute of Environmental Health Sciences) New research from the National Institutes of Health found that pairing the antidepressant amitriptyline with drugs designed to treat central nervous system diseases, enhances drug delivery to the brain by inhibiting the blood-brain barrier in rats. The blood-brain barrier serves as a natural, protective boundary, preventing most drugs from entering the brain. The research, performed in rats, appeared online April 27 in the Journal of Cerebral Blood Flow and Metabolism. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 27, 2017 Category: Biology Source Type: news
