The use of LNG-IUS-19.5 mg in daily gynecological routine practice in Germany: data from the Kyleena™ Satisfaction Study (KYSS)
ConclusionOur real-world findings on LNG-IUS-19.5 mg use in German KYSS participants reflected its suitability for a broad population, including young and nulliparous women.Clinical trial registrationNCT03182140 (date of registration: June 2017). (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 16, 2024 Category: OBGYN Source Type: research
Magnetic resonance imaging features of complete androgen insensitivity syndrome in comparison to Mayer-Rokitansky-K üster-Hauser syndrome
ConclusionsMRI features of detectable vagina, location of nodular and cystic structures, number of cysts within the cystic structures, signal intensity on DWI and ADC values of the nodular structures were useful in differentiating CAIS from MRKHS.Graphical Abstract (Source: Abdominal Imaging)
Source: Abdominal Imaging - April 11, 2024 Category: Radiology Source Type: research
A rare cause of amenorrhea: Hematocolpos in a post ‐cystocele repair patient
We present the case of a 48-year-old female who presented with amenorrhea and abdominal pain following surgical repair of a cystocele. Investigation revealed secondary hematocolpos due to surgical trauma. Surgical drainage and correction of the uterus were performed, resulting in immediate pain relief. This case underscores the importance of considering hematocolpos in patients with post-surgical amenorrhea, and further research is needed to better understand its causes, risk factors, and optimal management strategies. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Tibyan Noorallah Mohammed,
Ammar Elgadi,
Gamal Mohi Eldeen Nuri Tags: CASE REPORT Source Type: research
Construction and Validation of a Clinical Prediction Model for Predicting Tubal Pregnancy Rupture Based on Nomogram
ConclusionsThe prediction model for tubal pregnancy rupture, based on the four predictors: amenorrhea duration, pregnancy site, serum β-HCG levels, and maximum diameter of the mass, demonstrated good predictive efficacy. (Source: The Journal of Obstetrics and Gynecology of India)
Source: The Journal of Obstetrics and Gynecology of India - April 5, 2024 Category: OBGYN Source Type: research
A retrospective study of ovarian tissue cryopreservation in female patients with hematological diseases for fertility preservation
ConclusionsOvarian tissue cryopreservation has a promising future in fertility protection in patients with hematological diseases. However, patients with hematological malignancies often have received gonadotoxic therapy before OTC, which may be accompanied by myelosuppression while patients with non-malignant hematological diseases often present with severe hemocytopenia. So perioperative complete blood count of patients should be paid attention to. There was no significant difference in the WBC count and hemoglobin concentration in patients with hematological diseases before and after OTC surgery, and the platelet count ...
Source: Archives of Gynecology and Obstetrics - April 4, 2024 Category: OBGYN Source Type: research
12. Recharacterizing Primary Amenorrhea in a Large Diverse Cohort
This study recharacterizes PA in a large racially and ethnically diverse cohort. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Megan Sumida, Elena Martinez, Davida Becker, Claire Templeman Source Type: research
2. Surgical Treatment of a Rare Case of 46,XY Disorder of Sexual Development
We present the surgical management of a 21-year-old patient with 46,XY PGD,who has predominantly female external genitalia with clitoral enlargement and complete vaginal agenesis. Our patient presented with primary amenorrhea and lack of breast development. Clitoral enlarge ment was present with a single urethral opening and absence of an external vaginal opening (Fig.1)Laboratory evaluation revealed low testosterone concentrations (0.3 ng/ml) with elevated FSH and LH leves.Total testosterone/dihydrotestosterone and androstenedione ratios were normal. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Ipek Evruke, Ozlem Dural, Funda Gungor Ugurlucan, Hevra Ekin Ulusoy, Inci Sema Tas, Cenk Yasa, Suleyman Engin Akhan Source Type: research
123. Suspected MRKH in the setting of primary amenorrhea and VACTERL
Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, affecting 1 in 5000 females, is a mullerian anomaly characterized by uterovaginal malformation with the diagnosis typically following investigation of primary amenorrhea (1). Vater Syndrome (VACTERL) is a broad term describing a constellation of congenital abnormalities with an estimated incidence of 1 in 10,000 to 40,000 births (2). Here we present a case of MRKH with co-existing VACTERL to highlight commonalities in presentation with the goal to improve knowledge, early identification, and opportunities for research. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Levon Agdere, Oksana Nulman, Marie Brunelli, Ashley Lekach, Angela Judd Source Type: research
119. Sclerosing Stromal Ovarian Tumors: A Rare Cause of Primary Amenorrhea and Hyperandrogenism in Adolescents
Sclerosing stromal tumors (SST) of the ovary are extremely rare sex cord-stromal tumors with about 200 cases reported in the literature. Most patients (70%) are between 14 and 29 years, and present with nonspecific symptoms of menstrual irregularity and pelvic pain. SSTs are usually benign, unilateral, well-circumscribed, non-hormone producing masses. This case describes a rare androgen-producing SST in an adolescent presenting with primary amenorrhea. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Rabab Isa, Lauren Taylor, Georgina Amaral, Olivia Winfrey Source Type: research
80. Management of Heavy Menstrual Bleeding in Transgender and Gender Diverse Adolescents and Young Adults
Transgender and gender diverse (TGD) individuals assigned female at birth (AFAB) often desire menstrual suppression due to dysphoria related to menses. Achieving amenorrhea may be more difficult in the setting of heavy menstrual bleeding (HMB) or a bleeding disorder (BD). The aim of this study was to investigate management patterns and rates of amenorrhea in TGD AFAB individuals with diagnoses of HMB and/or a BD. A secondary aim was to examine the influence of testosterone (T) on achieving amenorrhea. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Kathleen O'Brien, Melina Dendrinos, Rebecca Warwick, Erin Isaacson, Monica Rosen Source Type: research
11. Accuracy of Imperforate Hymen Diagnosis at a Pediatric and Adolescent Gynecology Referral Center
Imperforate hymen (IH) is a congenital anomaly (CA) that results from unsuccessful canalization of the vaginal plate at the junction of the urogenital sinus (UGS) and uterovaginal canal and failed canalization of hymenal mucosa. IH is often discovered at puberty due to primary amenorrhea and cyclic pelvic pain secondary to vaginal outlet obstruction. The hymen and M üllerian system have different embryonic origins and it is important to distinguish congenital conditions based on their embryonic origins. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Sarah Casey, Mary Fang, Kassandra Goytia, Gianina Monestime, Jennifer Dietrich Source Type: research
5. A Rare Combination: Uterine and Distal Vaginal Agenesis with Symptomatic Hydrocolpos
We present a rare case of uterine agenesis with DVA presenting as primary amenorrhea and dilated upper vagina leading to pelvic pain managed by laparoscopic drainage of hydrocolpos. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Jessica Smith, Krista Childress Source Type: research
Body weight variation is not an independent factor in the determination of functional hypothalamic amenorrhea in anorexia nervosa
ConclusionsFHA does not correlate strictly with body weight variations in AN patients, indicating a multifactorial origin, likely including an individual predisposition. Higher FT3 levels identify patients who continue having menses at extremely low BMI. AN patients with persistent FHA constitute a subgroup in whom estroprogestins should be considered after significant weight recovery to prevent prolonged tissue hypoestrogenism. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 29, 2024 Category: Endocrinology Source Type: research
Cervical atresia and an obliterated upper vagina presenting as primary amenorrhea
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 28, 2024 Category: OBGYN Authors: Rebecca J. MEISER, Toni S. HORTON, Aakriti R. CARRUBBA, Sherif A. EL-NASHAR, Anita H. CHEN Tags: Images in Gynecology Source Type: research
