Prescription sleeping pills like Ambien may raise the risk of dementia by 80 PERCENT
San Francisco-based researchers found older adults who took sleeping pills frequently were nearly 80 percent more likely to develop dementia compared to people who rarely take them. (Source: the Mail online | Health)
Source: the Mail online | Health - February 1, 2023 Category: Consumer Health News Source Type: news

Required performance of road projection lamp for vehicle reversing - Shibata Y, Kito M, Ishida H, Goto Y, Kamijo M.
We report the required performance of road projection lamp for vehicle reversing. We conducted experiment at outside that simulated the ambien... (Source: SafetyLit)
Source: SafetyLit - January 2, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Why zolpidem increases the risk of falls and fractures in patients with cirrhosis - Weersink RA, Drenth JPH, Borgsteede SD.
We thank Tapper and colleagues for their interesting and relevant article on deprescribing benzodiazepines in patients with cirrhosis. The authors conclude that deprescribing zolpidem reduces the risk of falls and fractures in these patients. Yet, the arti... (Source: SafetyLit)
Source: SafetyLit - October 26, 2022 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

America's Love Affair With Sleeping Pills May Be Waning
WEDNESDAY, Aug. 24, 2022 -- Fewer Americans are turning to sleep medications to fight insomnia. After a dramatic rise in prescriptions for drugs like Ambien, the trend has ebbed, according to a new study, and fewer doctors are prescribing sleep... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 24, 2022 Category: General Medicine Source Type: news

Zolpidem use and risk of suicide: a systemic review and meta-analysis - Khan H, Garg A, Yasmeen, Agarwal NB, Yadav DK, Khan MA, Hussain S.
Introduction : Zolpidem is one of the most commonly prescribed nonbenzodiazepine hypnotic drugs for insomnia. Published epidemiological studies linked zolpidem with the risk of suicide. However, to date, no meta-analysis investigated this association. Hen... (Source: SafetyLit)
Source: SafetyLit - August 18, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Falls, healthcare resources and costs in older adults with insomnia treated with zolpidem, trazodone, or benzodiazepines - Amari DT, Juday T, Frech FH, Wang W, Wu Z, Atkins NJ, Wickwire EM.
BACKGROUND: Falls are the leading cause of injury-related death among older Americans. While some research has found that insomnia heightens falls, health care resource utilization (HCRU) and costs, the impact of insomnia treatments on fall risk, mortality... (Source: SafetyLit)
Source: SafetyLit - June 8, 2022 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

App-based treatment for people with insomnia
NICE has recommended Sleepio as an effective alternative to sleeping pills, which would save the NHS money as well as reducing prescriptions of medicines such as zolpidem and zopiclone that can be dependency forming. (Source: NHS Networks)
Source: NHS Networks - May 24, 2022 Category: UK Health Source Type: news

Zolpidem Restrictions: How Are General Practitioners Coping? Zolpidem Restrictions: How Are General Practitioners Coping?
Most practitioners who participated in a French study described the restrictions as helpful for promoting discontinuation and, at the same time, problematic.Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - May 23, 2022 Category: Primary Care Tags: Neurology & Neurosurgery News Source Type: news

Up to 800,000 insomniacs reliant on drugs can now be given app which helps them sleep easier
Around 800,000 people in England struggling to sleep, who would usually be offered pills such as zolpidem and zopiclone, are set to be recommended Sleepio. (Source: the Mail online | Health)
Source: the Mail online | Health - May 19, 2022 Category: Consumer Health News Source Type: news

Cost-effectiveness analysis of lemborexant for treating insomnia in Japan: a model-based projection, incorporating the risk of falls, motor vehicle collisions, and workplace accidents - Ikeda S, Azuma M, Fujimoto K, Shibahara H, Inoue S, Moline M, Ishii M, Mishima K.
BACKGROUND: Lemborexant has demonstrated statistically significant improvements in sleep onset and sleep maintenance compared with placebo and zolpidem tartrate extended release, measured both objectively using polysomnography and subjectively using sleep ... (Source: SafetyLit)
Source: SafetyLit - May 6, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Deprescribing zolpidem reduces falls and fractures in patients with cirrhosis - Tapper EB, Zhao Z, Winder GS, Parikh ND.
BACKGROUND& AIMS: Benzodiazepines are associated with an increased risk of harm in patients with cirrhosis. However, stopping benzodiazepines must be done with care to avoid withdrawal or other unintended consequences. The impact of deprescribing on patie... (Source: SafetyLit)
Source: SafetyLit - May 4, 2022 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Pharmacist Indicted for Tampering with a Controlled Substance
FDA OCI, Benjamin Dandurand, Shawnee Mission KS, pharmacist, tampering, controlled substance, Tramadol, Zolpidem, oxycodone hydrochloride, indictment, consumer protection, opioids, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - February 25, 2022 Category: Medical Law Authors: DOJ Source Type: news

Fall risk, healthcare resource use, and costs among adult patients in the United States treated for insomnia with zolpidem, trazodone, or benzodiazepines: a retrospective cohort study - Amari DT, Juday TR, Frech FH, Wang W, Gor D, Atkins NJ, Wickwire EM.
The objective of this study is to compare the risk of falls, all-cause healthcare resource utilization (HCRU), and costs among patien... (Source: SafetyLit)
Source: SafetyLit - January 27, 2022 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Prevalence and concentrations of sedative-hypnotic drugs in blood of drivers involved in road traffic crashes in the Padova region of Italy - not so easy to interpret - Favretto D, Visentin S, Jones AW.
This study reports the prevalence and concentrations of sedative-hypnotic drugs as exemplified by benzodiazepines (BZD) and zolpidem (Z-hypnotic) in blood samples from drivers involved in road traffic accidents (RTA) in the Padova ... (Source: SafetyLit)
Source: SafetyLit - November 29, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Zolpidem: efficacy and side effects for insomnia - Edinoff AN, Wu N, Ghaffar YT, Prejean R, Gremillion R, Cogburn M, Chami AA, Kaye AM, Kaye AD.
PURPOSE OF REVIEW: Insomnia is a common type of sleep disorder defined by an ongoing difficulty initiating or maintaining sleep or nonrestorative sleep with subsequent daytime impairment. The sleep disturbances in insomnia usually manifest as difficulty in... (Source: SafetyLit)
Source: SafetyLit - November 10, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news