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Bonus Features – October 16, 2022 – Half of docs considering leaving their job, there ’ s little risk in sharing de-identified data, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News A report from recruitment firm Jackson Physician Search and MGMA found that physician burnout is bad and getting worse. Nearly two-thirds of physicians surveyed (65%) said they are experiencing burnout, and 35% said their l...
Source: EMR and HIPAA - October 16, 2022 Category: Information Technology Authors: Brian Eastwood Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System CCS CHIME CIvitas Conifer Health CyberReef Daniel Barchi De-Identified Patient Data Elixir Epic Epic Together GetWell GoodRx Google Cloud Gravity Source Type: blogs

Using FibroScan in The Clinic: Interview with Dr. Stephen A. Harrison
EchoSens creates non-invasive liver diagnosis medical devices. The company’s line of products, called FibroScan, work by measuring the speed of ultrasound waves as they move through liver tissue. This measurement can tell us about the state of the liver. For example, ultrasound waves move faster through fibrotic/scarred livers. EchoSens recently appointed Dominique Legros as their new global CEO, and we recently spoke about his plans for growth in a Medgadget exclusive. To learn more about how a clinician would use the FibroScan, we spoke with Dr. Stephen A. Harrison, Medical Director of Pinnacle Clinical Re...
Source: Medgadget - September 30, 2019 Category: Medical Devices Authors: Ben Ouyang Tags: Diagnostics Exclusive GI Medicine Source Type: blogs

23andMe ’s Pharmacogenetic Test Approved by FDA
The FDA has just approved 23andMe’s Personal Genomic Service (PGS) Pharmacogenetic Reports. This marks the first direct-to-consumer test for pharmacogenetics of enzyme variants that may affect the way patients break down medications. Consumers collect their saliva into 23andMe’s testing kit, mail it to the company’s labs, and then receive the results via an online portal. The approved pharmacogenetic assessment system looks for 33 variants of common enzymes that affect medication metabolism, including CYP2C19, CYP2C9, CYP3A5, UGT1A1, DPYD, TPMT, SLCO1B1, and CYP2D6. The full list of variants can be found ...
Source: Medgadget - November 1, 2018 Category: Medical Devices Authors: Ben Ouyang Tags: Diagnostics Genetics News Source Type: blogs

Rare Diseases Account for Subsets of Common Diseases
In June, 2014, my book, entitled Rare Diseases and Orphan Drugs: Keys to Understanding and Treating the Common Diseases was published by Elsevier. The book builds the argument that our best chance of curing the common diseases will come from studying and curing the rare diseases. One of the key messages of the book is that common diseases are complex, with multiple causes, lots of associated gene variations, many different aberrant pathways, and affecting heterogeneous populations (e.g., subsets of people who seem to have clinically distinctive forms of the same disease, or subsets of people who respond quite different...
Source: Specified Life - June 22, 2014 Category: Pathologists Tags: cellular pathways common genetic disease complex diseases disease pathways heterogeneous subsets of disease orphan diseases orphan drugs rare diseases Source Type: blogs

FDA: Enhancing Benefit-Risk Assessment in Regulatory Decision Making
Last summer, Congress enacted the Food and Drug Administration Safety and Innovation Act (FDASIA), which included the fifth authorization of the Prescription Drug User Fee Act (PDUFA V). Title I of FDASIA reauthorizes the Prescription Drug User Fee Act (PDUFA), which provides FDA with the necessary user fee resources to maintain an efficient review process for human drug and biologic products. The reauthorization of PDUFA includes performance goals and procedures that represent FDA’s commitments during FY 2013-2017. These commitments are referred to in section 101 of FDASIA. Section X of these commitments relates ...
Source: Policy and Medicine - April 25, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs

Peptic Ulcer Disease
Pathophysiology of Peptic Ulcer Disease 1) peptic ulcer disease is marked by a break in mucosal lining of stomach and duodenum 2) main causes are infection with Helicobacter pylori and use of NSAIDs Signs and Symptoms 1) burning epigastric pain relieved by antacids and eating 2) epigastric pain causing patient to wake up in the middle of the night 3) chest pain mimicking angina 4) epigastric tenderness 5) gastrointestinal bleeding (15%) with coffee-ground emesis or vomiting bright red blood or lower gastrointestinal bleeding 6) perforation (8%) with peritonitis and rigid abdomen 7) duodenal obstruction (3%) with nausea and...
Source: Inside Surgery - February 24, 2013 Category: Surgeons Authors: Editor Tags: Gastroenterology Source Type: blogs

USMLE Questions – Characteristic Disease Findings
The United States Medical Licensing Examination (USMLE) is designed to emphasize knowledge of clinical scenarios and clinical pearls, even on Step I. Listed below are some commonly encountered disease findings and characteristics. Feature Disease 45, X chromosome Turner’s syndrome 5-HIAA increased in urine Carcinoid syndrome Aganglionic rectum Hirschsrpung’s disease Apple-core sign on barium enema Colon cancer Arched back (opisthotonos) Tetanus Argyll-Robertson pupil Syphilis Ash leaf on forehead Tuberous sclerosis Auer rods Acute myelogenous leukemia Austin Flint murmur Aortic regurgitation...
Source: Inside Surgery - January 18, 2013 Category: Surgeons Authors: Editor Tags: Surgpedia USMLE diseases findings VMA water hammer pulse Source Type: blogs