Molecules, Vol. 29, Pages 1144: SAR, Molecular Docking and Molecular Dynamic Simulation of Natural Inhibitors against SARS-CoV-2 Mpro Spike Protein
riq Mahmood
The SARS-CoV-2 virus and its mutations have affected human health globally and created significant danger for the health of people all around the world. To cure this virus, the human Angiotensin Converting Enzyme-2 (ACE2) receptor, the SARS-CoV-2 main protease (Mpro), and spike proteins were found to be likely candidates for the synthesis of novel therapeutic drug. In the past, proteins were capable of engaging in interaction with a wide variety of ligands, including both manmade and plant-derived small molecules. Pyrus communis L., Ginko bibola, Carica papaya, Syrian rue, and Pimenta dioica were some of th...
Source: Molecules - March 4, 2024 Category: Chemistry Authors: Aqsa Salamat Naveen Kosar Ayesha Mohyuddin Muhammad Imran Muhammad Nauman Zahid Tariq Mahmood Tags: Article Source Type: research
Longitudinal observational study protocol - Preterm Infants: Microbiome Establishment, Neuro-CrossTalk and Origins (PIMENTO)
The objective of this study is to determine detailed microbiome changes that occur around implementation of different management practices including empiric antibiotic use, advancement of feeds and administration of probiotics during admission to the neonatal intensive care unit.
Methods and analysis
A single-site, longitudinal observational study of infants born less than 32 weeks gestation, including collection of maternal samples around delivery and breastmilk and infant samples from admission through discharge from the neonatal unit.
Ethics and dissemination
The protocol was approved by the Clinical Research Ethics C...
Source: BMJ Open - September 25, 2023 Category: General Medicine Authors: Healy, D., Wang, S., Grimaud, G., Warda, A. K., Ross, P., Stanton, C., Dempsey, E. M. Tags: Open access, Paediatrics Source Type: research
Characterization and Pharmacokinetic Profile of Herbs and Spices' Phytochemicals over 24 h after Consumption in Overweight/Obese Adults
ConclusionPhytochemicals from H/S include in a meal are absorbed and undergo phase I and phase II metabolism and/or catabolized to phenolic acids peaking at different times. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 13, 2023 Category: Food Science Authors: Yudai Huang,
Indika Edirisinghe,
Britt M. Burton ‐Freeman,
Amandeep K. Sandhu Tags: Research Article Source Type: research
FEMA GRAS assessment of natural flavor complexes: Allspice, anise, fennel-derived and related flavoring ingredients
Food Chem Toxicol. 2023 Feb 3:113643. doi: 10.1016/j.fct.2023.113643. Online ahead of print.ABSTRACTThe FEMA Expert Panel program to re-evaluate the safety of natural flavor complexes (NFCs) used as flavoring ingredients in food has resulted in the publication of an updated constituent-based procedure as well as publications on the safety evaluation of many botanical-derived NFCs. This publication, tenth in the series and related to the ninth publication, describes the affirmation of the generally recognized as safe (GRAS) status for NFCs with propenylhydroxybenzene and allylalkoxybenzene constituents under their condition...
Source: Food and Chemical Toxicology - February 5, 2023 Category: Food Science Authors: Ivonne M C M Rietjens Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham F Peter Guengerich Stephen S Hecht Thomas J Rosol Jeanne M Davidsen Christie L Harman Sean V Taylor Source Type: research
FEMA GRAS assessment of natural flavor complexes: Allspice, anise, fennel-derived and related flavoring ingredients
Food Chem Toxicol. 2023 Feb 3:113643. doi: 10.1016/j.fct.2023.113643. Online ahead of print.ABSTRACTThe FEMA Expert Panel program to re-evaluate the safety of natural flavor complexes (NFCs) used as flavoring ingredients in food has resulted in the publication of an updated constituent-based procedure as well as publications on the safety evaluation of many botanical-derived NFCs. This publication, tenth in the series and related to the ninth publication, describes the affirmation of the generally recognized as safe (GRAS) status for NFCs with propenylhydroxybenzene and allylalkoxybenzene constituents under their condition...
Source: Food and Chemical Toxicology - February 5, 2023 Category: Food Science Authors: Ivonne M C M Rietjens Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham F Peter Guengerich Stephen S Hecht Thomas J Rosol Jeanne M Davidsen Christie L Harman Sean V Taylor Source Type: research
FEMA GRAS assessment of natural flavor complexes: Allspice, anise, fennel-derived and related flavoring ingredients
Food Chem Toxicol. 2023 Feb 3:113643. doi: 10.1016/j.fct.2023.113643. Online ahead of print.ABSTRACTThe FEMA Expert Panel program to re-evaluate the safety of natural flavor complexes (NFCs) used as flavoring ingredients in food has resulted in the publication of an updated constituent-based procedure as well as publications on the safety evaluation of many botanical-derived NFCs. This publication, tenth in the series and related to the ninth publication, describes the affirmation of the generally recognized as safe (GRAS) status for NFCs with propenylhydroxybenzene and allylalkoxybenzene constituents under their condition...
Source: Food and Chemical Toxicology - February 5, 2023 Category: Food Science Authors: Ivonne M C M Rietjens Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham F Peter Guengerich Stephen S Hecht Thomas J Rosol Jeanne M Davidsen Christie L Harman Sean V Taylor Source Type: research
FEMA GRAS assessment of natural flavor complexes: Allspice, anise, fennel-derived and related flavoring ingredients
Food Chem Toxicol. 2023 Feb 3:113643. doi: 10.1016/j.fct.2023.113643. Online ahead of print.ABSTRACTThe FEMA Expert Panel program to re-evaluate the safety of natural flavor complexes (NFCs) used as flavoring ingredients in food has resulted in the publication of an updated constituent-based procedure as well as publications on the safety evaluation of many botanical-derived NFCs. This publication, tenth in the series and related to the ninth publication, describes the affirmation of the generally recognized as safe (GRAS) status for NFCs with propenylhydroxybenzene and allylalkoxybenzene constituents under their condition...
Source: Food and Chemical Toxicology - February 5, 2023 Category: Food Science Authors: Ivonne M C M Rietjens Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham F Peter Guengerich Stephen S Hecht Thomas J Rosol Jeanne M Davidsen Christie L Harman Sean V Taylor Source Type: research
Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology
Appl Biochem Biotechnol. 2022 Oct 11. doi: 10.1007/s12010-022-04132-y. Online ahead of print.ABSTRACTMedicinal or herbal spices are grown in tropical moist evergreen forestland, surrounding most of the tropical and subtropical regions of Eastern Himalayas in India (Sikkim, Darjeeling regions), Bhutan, Nepal, Pakistan, Iran, Afghanistan, a few Central Asian countries, Middle East, USA, Europe, South East Asia, Japan, Malaysia, and Indonesia. According to the cultivation region surrounded, economic value, and vogue, these spices can be classified into major, minor, and colored tropical spices. In total, 24 tropical spices an...
Source: Applied Biochemistry and Biotechnology - October 11, 2022 Category: Biochemistry Authors: Debopriya Mandal Tanmay Sarkar Runu Chakraborty Source Type: research
Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology
Appl Biochem Biotechnol. 2022 Oct 11:1-195. doi: 10.1007/s12010-022-04132-y. Online ahead of print.ABSTRACTMedicinal or herbal spices are grown in tropical moist evergreen forestland, surrounding most of the tropical and subtropical regions of Eastern Himalayas in India (Sikkim, Darjeeling regions), Bhutan, Nepal, Pakistan, Iran, Afghanistan, a few Central Asian countries, Middle East, USA, Europe, South East Asia, Japan, Malaysia, and Indonesia. According to the cultivation region surrounded, economic value, and vogue, these spices can be classified into major, minor, and colored tropical spices. In total, 24 tropical spi...
Source: Applied Biochemistry and Biotechnology - October 11, 2022 Category: Biochemistry Authors: Debopriya Mandal Tanmay Sarkar Runu Chakraborty Source Type: research
Severe Allergic Reaction to Allspice, a Hidden Food Allergen
Ann Allergy Asthma Immunol. 2022 May 13:S1081-1206(22)00404-5. doi: 10.1016/j.anai.2022.04.036. Online ahead of print.NO ABSTRACTPMID:35577235 | DOI:10.1016/j.anai.2022.04.036 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - May 16, 2022 Category: Allergy & Immunology Authors: Prudhvi Regula Deborah Edelman Denisa Ferastaoaru Manish Ramesh Golda Hudes Source Type: research
Severe Allergic Reaction to Allspice, a Hidden Food Allergen
Ann Allergy Asthma Immunol. 2022 May 13:S1081-1206(22)00404-5. doi: 10.1016/j.anai.2022.04.036. Online ahead of print.NO ABSTRACTPMID:35577235 | DOI:10.1016/j.anai.2022.04.036 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - May 16, 2022 Category: Allergy & Immunology Authors: Prudhvi Regula Deborah Edelman Denisa Ferastaoaru Manish Ramesh Golda Hudes Source Type: research
Severe Allergic Reaction to Allspice, a Hidden Food Allergen
Ann Allergy Asthma Immunol. 2022 May 13:S1081-1206(22)00404-5. doi: 10.1016/j.anai.2022.04.036. Online ahead of print.NO ABSTRACTPMID:35577235 | DOI:10.1016/j.anai.2022.04.036 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - May 16, 2022 Category: Allergy & Immunology Authors: Prudhvi Regula Deborah Edelman Denisa Ferastaoaru Manish Ramesh Golda Hudes Source Type: research
Severe allergic reaction to allspice, a hidden food allergen
A wide variety of spices are in culinary use for food flavoring, coloring, and preservation.1 Spice allergy is uncommon, and it is estimated that around 2% of food allergy reactions in adults are caused by spices.2 Spices have the potential for being hidden food allergens.3 The allergenic proteins in spices are not well characterized, and commercial skin test extracts are not available, limiting widespread clinical testing. For these reasons, spice allergy is likely underdiagnosed. Common spices that are reported to cause allergies include mustard, coriander or cilantro, fennel, saffron, parsley, and cumin. (Source: Annals...
Source: Annals of Allergy, Asthma and Immunology - May 13, 2022 Category: Allergy & Immunology Authors: Prudhvi Regula, Deborah Edelman, Denisa Ferastraoaru, Manish Ramesh, Golda Hudes Tags: Letters Source Type: research
Severe Allergic Reaction to Allspice, a Hidden Food Allergen.
A wide variety of spices are in culinary use for food flavoring, coloring, and preservation.1 Spice allergy is uncommon, and it is estimated that around 2% of food allergy reactions in adults are caused by spices.2 Spices have the potential for being hidden food allergens.3 The allergenic proteins in spices are not well characterized, and commercial skin test extracts are not available, limiting widespread clinical testing. For these reasons, spice allergy is likely underdiagnosed. Common spices that are reported to cause allergies include mustard, coriander or cilantro, fennel, saffron, parsley, and cumin. (Source: Annals...
Source: Annals of Allergy, Asthma and Immunology - May 13, 2022 Category: Allergy & Immunology Authors: Prudhvi Regula, Deborah Edelman, Denisa Ferastaoaru, Manish Ramesh, Golda Hudes Tags: Letters Source Type: research
Molecules, Vol. 26, Pages 6698: Chemical Composition, Insecticidal and Mosquito Larvicidal Activities of Allspice (Pimenta dioica) Essential Oil
a Barcelo
Essential oils are biologically and environmentally safe pesticidal compounds yielded from aromatic plants. Spices are important sources of essential oils, and they are widely used in the medicine, food, and various other industries. Among the different spices, Allspice (Pimenta dioica) is underexplored in terms of its biological efficacy and a limited number of studies are available on the chemical composition of Allspice essential oil (AEO); thus, the present study evaluated the larvicidal property, the repellency, and the fumigant toxicity against common pests of stored products of AEO. AEO was found to in...
Source: Molecules - November 5, 2021 Category: Chemistry Authors: Arunaksharan Narayanankutty Aswathi Moothakoottil Kuttithodi Ahmed Alfarhan Rajakrishnan Rajagopal Damia Barcelo Tags: Article Source Type: research
