Stepwise Heat-Denaturated Protein Introduction for Tolerance Induction in Food Allergy
Conditions: Food Allergy; Cow Milk Allergy Interventions: Other: Implementation of cow ' s milk in decreasingly heated forms; Other: Implementation of heated cow ' s milk; Other: No intervention Sponsors: Universitaire Ziekenhuizen KU Leuven Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

Tolerance induction through early feeding to prevent food allergy in infants and children with sensitization against food allergens (TIFFANI): rationale, study design, and methods of a randomized controlled trial
DiscussionChildren with sensitization against food allergens with unknown clinical relevance often have to avoid the corresponding foods for several months until an OFC is performed. Therefore, the “window of opportunity” for an early preventive introduction of allergenic foods might be missed. This trial will assess whether an introduction of small allergen amounts will favor tolerance development in these children.Trial registrationGerman Clinical Trials Register DRKS00032769. Registered on 02 October 2023. (Source: Trials)
Source: Trials - April 19, 2024 Category: Research Source Type: clinical trials

Short-Term Linvoseltamab Treatment, on Top of Chronic Dupilumab Treatment, for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy
Conditions: Food Allergy Interventions: Drug: linvoseltamab; Drug: dupilumab Sponsors: Regeneron Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials

One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis
Conditions: Fascioliasis Interventions: Drug: Oxfendazole; Drug: Triclabendazole Sponsors: Universidad Peruana Cayetano Heredia; National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantation
Conditions: Autoimmunity; Inguinal Hernia; Stress Urinary Incontinence; Pelvic Organ Prolapse; Implant Complication; Systemic Autoimmune Disease Interventions: Diagnostic Test: mesh allergy test; Diagnostic Test: blood tests; Procedure: Mesh removal Sponsors: Maxima Medical Center; Amsterdam UMC; Maastricht University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study
Conditions: Lymphohistiocytosis, Hemophagocytic; Secondary Hemophagocytic Lymphohistiocytosis; Macrophage Activation Syndrome; Hyperinflammatory Syndromes Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 1, 2024 Category: Research Source Type: clinical trials

Cali Sin Tos Aim 2
Conditions: Tuberculosis Interventions: Device: Chatbot; Diagnostic Test: Oral testing Sponsors: Yale University; National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials

CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy
Conditions: HIV-1-infection; Pregnancy; Postpartum Interventions: Drug: CAB LA 600mg; Drug: RPV LA 900mg; Drug: CAB LA 400mg; Drug: RPV LA 600mg Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 28, 2024 Category: Research Source Type: clinical trials

Comparison Effectiveness of Oral Ivermectin , 1% Permethrin Shampoo and 4% Dimeticone Liquid Gel in the Treatment of Pediculosis Capitis Among School Children in Chachoengsao Province, Thailand
Conditions: Pediculus Capitis Infestation; Permethrin Adverse Reaction; Dimethicone Adverse Reaction; Permethrin Allergy; Dimethicone Allergy; Ivermectin; School-age Children Interventions: Drug: Oral Ivermectin; Drug: 4% dimenticone liquid gel Sponsors: Phramongkutklao College of Medicine and Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 27, 2024 Category: Research Source Type: clinical trials

Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.
Conditions: HIV Interventions: Biological: 16055 NFL delta Gly4 trimer; Biological: Trimer 4571; Biological: Ad4-Env145NFL, 5 x 108 viral particles (vp) Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 27, 2024 Category: Research Source Type: clinical trials

TREATment of Lower Respiratory Tract Infection in Sri Lanka (TREAT-SL)
Conditions: Lower Resp Tract Infection Interventions: Other: electronic clinical decision support tool (eCDST) diagnostic plan Sponsors: Duke University; National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials

Allergy, Asthma, and Atopic Eczema in Finland
Conditions: Asthma; Asthma in Children; Allergy; Rhinitis, Allergic; Atopic Dermatitis; Allergen Immunotherapy Interventions: Other: No intervention Sponsors: Tampere University; Professor Lauri Lehtim äki; Professor Mika Mäkelä; Professor Sanna Toppila-Salmi; Professor Ilkka Junttila Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IGNX001
Conditions: Peanut Allergy Interventions: Drug: IGNX001; Drug: Placebo Sponsors: IgGenix Australia Pty Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials

A Prospective Birth Cohort of Infants With Allergy and Neurodevelopmental Disorders in China
Conditions: Child Allergy; Neurodevelopmental Disorders Sponsors: Qilu Hospital of Shandong University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials

Efficacy of Cashew Nut Protein Immunotherapy
Conditions: Food Allergy Interventions: Combination Product: Cashew immunotherapy Sponsors: Medical University of Warsaw Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials