Experimental Study on the Protection of Agrimony Extracts from Different Extracting Methods against Cerebral Ischemia-Reperfusion Injury
ConclusionsTreatment using water extracts of agrimony can promote the best functional and metabolic recovery for rat model of cerebral ischemia-reperfusion injury, which maybe relate with the upregulation of energy metabolism in nerve cells after MCAO. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Anti-Nociceptive Effect and Standardization from Mixture of Agrimonia pilosa Ledeb and Salvia miltiorrhiza Bunge Extracts
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - May 30, 2018 Category: Nutrition Authors: Seung Hwan Hwang Set Byeol Kim Sang-Pil Jang Zhiqiang Wang Hong-Won Suh Soon Sung Lim Source Type: research
Preclinical Hepatoprotective Effect of Herbalism against Ethanol Induced Hepatotoxicity: A Review.
Abstract
Liver ailments including alcoholic liver disease (ALD), still remain the main reason for morbidity & mortality worldwide. In fact, ALD is a multifactorial disease with complex pathophysiology which is linked to several types of liver damages including steatohepatitis, fibrosis and cirrhosis. This review emphasizes on 30 herbal medicinal plants with their extracts studied for protective effect against ALD and current scientific evidence of ALD cure by thirty Indian Materia Medica including Tilia Platyphyllos, Amomum subulatum, Carica papaya, Pogostemon patchouli, Commelina benghalensis, Bacopam...
Source: Current Drug Metabolism - March 30, 2018 Category: Drugs & Pharmacology Authors: Firdous H, Hussain T, Singh M, Rizvi SMD, Moin A, Kamal MA Tags: Curr Drug Metab Source Type: research
Anti-Helicobacter pylori potential of Agrimonia eupatoria L. and Fragaria vesca
Publication date: May 2018 Source:Journal of Functional Foods, Volume 44 Author(s): Olga Cardoso, Maria Manuel Donato, Cristina Luxo, Nuno Almeida, Joana Liberal, Artur Figueirinha, Maria Teresa Batista Helicobacter pylori (H. pylori) plays a causal role in chronic gastritis, peptic ulcer and gastric cancer. Antibiotic resistance and side effects of therapy have led to research for new candidates. Susceptibility and virulence factors were studied in H. pylori 12 clinical isolates. Agrimonia eupatoria L. (Ag), Fragaria vesca (Fv) extracts and a Fv ellagitannin-enriched fraction (Fve) activity were tested against th...
Source: Journal of Functional Foods - March 23, 2018 Category: Nutrition Source Type: research
Agrimonia eupatoria L. (Agrimony) Extract Alters Liver Health in Subjects with Elevated Alanine Transaminase Levels: A Controlled, Randomized, and Double-Blind Trial
Journal of Medicinal Food , Vol. 0, No. 0. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - February 27, 2018 Category: Nutrition Authors: Young Mi Cho Jeong Eun Kwon Minkyung Lee Youngsung Lea Do-Yong Jeon Hyeong Jun Kim Se Chan Kang Source Type: research
Agrimonia eupatoria L. (Agrimony) Extract Alters Liver Health in Subjects with Elevated Alanine Transaminase Levels: A Controlled, Randomized, and Double-Blind Trial
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - February 27, 2018 Category: Nutrition Authors: Young Mi Cho Jeong Eun Kwon Minkyung Lee Youngsung Lea Do-Yong Jeon Hyeong Jun Kim Se Chan Kang Source Type: research
The isolation, structural characterization and anti-osteosarcoma activity of a water soluble polysaccharide from Agrimonia pilosa
Publication date: 1 May 2018 Source:Carbohydrate Polymers, Volume 187 Author(s): Wei Huang, Huan Deng, Shengyang Jin, Xuan Ma, Kun Zha, Mao Xie A homogenous polysaccharide (APP), with a molecular weight of 120 kDa, was isolated from the dried aerial parts of Agrimonia pilosa. Gas chromatography (GC) and GC–MS analysis revealed that APP has a backbone of 1,3-linked Glcp and 1,3, 6-linked Glcp, and branched with 1-linked Glcp terminal along the main chain in a relative ratio of 2:1:1. We investigated the response of human osteosarcoma U-2 OS cells to APP treatment. MTT result showed that APP significantly inhibit...
Source: Carbohydrate Polymers - February 4, 2018 Category: Biomedical Science Source Type: research
Experimental Study on the Protection of Agrimony Extracts from Different Extracting Methods against Cerebral Ischemia-Reperfusion Injury
Conclusions Treatment using water extracts of agrimony can promote the best functional and metabolic recovery for rat model of cerebral ischemia-reperfusion injury, which maybe relate with the upregulation of energy metabolism in nerve cells after MCAO. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - February 1, 2018 Category: General Medicine Source Type: research
Morphological changes of bacterial cells upon exposure of silver-silver chloride nanoparticles synthesized using Agrimonia pilosa
Publication date: March 2018 Source:Microbial Pathogenesis, Volume 116 Author(s): Maheshkumar Prakash Patil, Yong Bae Seo, Gun-Do Kim Facile, eco-friendly synthesis of metal nanoparticles has been proposed as a cost effective method. In the present study, we propose the facile synthesis of silver-silver chloride (Ag-AgCl) nanoparticles (NPs) using the medicinally important Agrimonia pilosa plant extract without addition of capping or stabilizing agents. The Ag-AgCl NPs synthesis was observed at 40 °C after 10 min incubation; the synthesis of Ag-AgCl NPs was indicated by color change and confirmed by UV-vis spectr...
Source: Microbial Pathogenesis - January 31, 2018 Category: Infectious Diseases Source Type: research
Genotoxicity and antioxidant activity of five Agrimonia and Filipendula species plant extracts evaluated by comet and micronucleus assays in human lymphocytes and Ames Salmonella/microsome test.
This study extends the knowledge on bioactivities of F. palmata, A. eupatoria, A. procera, F. ulmaria and F. vulgaris by comprehensive characterization of their methanolic extracts. Antioxidant properties of extracts were evaluated by DPPH• (2,2-diphenyl-1-picrylhydrazyl), ABTS•+ 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) scavenging and oxygen radical absorbance capacities (ORAC). Genotoxicity of extracts was tested using alkaline single-cell gel electrophoresis (comet) and cytokinesis-block micronucleus assays in human lymphocytes in vitro and the Ames Salmonella/microsome test. All investigated Agrimonia ...
Source: Food and Chemical Toxicology - December 18, 2017 Category: Food Science Authors: Pukalskienė M, Slapšytė G, Dedonytė V, Lazutka JR, Mierauskienė J, Venskutonis PR Tags: Food Chem Toxicol Source Type: research
PTP1B inhibitory and cytotoxic activities of triterpenoids from the aerial parts of Agrimonia pilosa
AbstractRecently, PTP1B inhibitors have become the frontier as possible targeting for anti-cancer and anti-diabetic drugs. Twelve triterpenoids from the aerial parts ofAgrimonia pilosa were investigated for PTP1B inhibitory and cytotoxic activities. In the results, compounds3 (IC50 = 0.50 μM) and7 (IC50 = 5.88 μM) were found to possess very powerful inhibitory activity against the PTP1B enzyme, comparable to the positive control ursolic acid (IC50 = 6.60 μM). In addition, compounds1,2,4, and10‒12 showed potent inhibitory effects against PTP1B, with an IC50 range of 13.48 ‒14.98 μM. In the kineti...
Source: Medicinal Chemistry Research - October 25, 2017 Category: Chemistry Source Type: research
The effects of flavonoid compound from Agrimonia pilosa Ledeb on promotting 3T3-L1 preadipocytes differentiation by activating PPAR γ partially
This study aimed to investigate the mechanism of intervening type II diabetes by flavonoid compound fromAgrimonia pilosa Ledeb in vitro. We found flavonoid compound exhibited moderate peroxisome proliferator-activated receptor gamma agonist activity which was lower than that of rosiglitazone by luciferase reporter assay. 3T3-L1 cell differentiation was induced typically in the presence of various concentrations of flavonoid compound or pioglitazone for assaying insulin sensitization. We found that flavonoid compound effectively promoted 3T3-L1 preadipocyte differentiation and lipid deposition, but its intensity was lower t...
Source: Medicinal Chemistry Research - October 25, 2017 Category: Chemistry Source Type: research
Agrimonia pilosa Ledeb. aqueous extract improves impaired glucose tolerance in high-fat diet-fed rats by decreasing the inflammatory response
Agrimonia pilosa Ledeb. is a medicinal plant with physiological activities such as anti-cancer, antioxidant, anti-inflammatory activities and in vitro anti-diabetic activity. However, ... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - September 5, 2017 Category: Complementary Medicine Authors: Hwan Hee Jang, Song Yee Nam, Mi Ju Kim, Jung Bong Kim, Jeong Sook Choi, Haeng Ran Kim and Young Min Lee Tags: Research article Source Type: research
Characterization of some potential medicinal plants from Central Europe by their antioxidant capacity and the presence of metal elements
Publication date: Available online 2 August 2017 Source:Food Bioscience Author(s): Michal Tupec, Veronika Hýsková, Kateřina Bělonožníková, Jakub Hraníček, Václav Červený, Helena Ryšlavá Plants contain polyphenolic compounds such as phenolic acids, flavonoids, stilbenes, lignans, etc., which are endowed with antioxidant properties. The aim of this study was to correlate the total phenolic compound and flavonoid content of 15 medicinal plants with their antioxidant properties and to determine some important essential elements (Na, K, Ca, Mg, Zn, Se). The antioxidant capacity was tested by three methods ...
Source: Food Bioscience - August 2, 2017 Category: Food Science Source Type: research
