Molecules, Vol. 28, Pages 1019: Effect of Agrimonia eupatoria L. and Origanum vulgare L. Leaf, Flower, Stem, and Root Extracts on the Survival of Pseudomonas aeruginosa
Ryšlavá
Pseudomonas aeruginosa is one of the most antibiotic multi-resistant bacteria, causing chronic pulmonary disease and leading to respiratory failure and even mortality. Thus, there has been an ever-increasing search for novel and preferably natural antimicrobial compounds. Agrimonia eupatoria L. and Origanum vulgare L. shoots are commonly used as teas or alcoholic tinctures for their human health-promoting and antibacterial properties. Here, we explored the antimicrobial effects of all plant parts, i.e., leaf, flower, stem, and root extracts, prepared in water or in 60% ethanol, against P. aeruginosa. The impa...
Source: Molecules - January 19, 2023 Category: Chemistry Authors: Kate řina Bělonožníková Eli ška Sladkovská Daniel Kavan Veronika H ýsková Petr Hodek Daniel Šmíd Helena Ry šlavá Tags: Article Source Type: research
Molecules, Vol. 28, Pages 713: Quantification and Validation of an HPLC Method for Low Concentrations of Apigenin-7-O-Glucuronide in Agrimonia pilosa Aqueous Ethanol Extract Topical Cream by Liquid & ndash;Liquid Extraction
In this study, we aimed to develop and validate a pretreatment method for separating and analyzing the small amounts of biomarkers contained in topical cream formulations. Analyzing semisolid formulations that contain low concentrations of active ingredients is difficult. Cream formulations containing an aqueous ethanol extract of 0.1% Agrimonia pilosa is an example. Approximately 0.0013% of apigenin-7-O-glucuronide(A7OG) was contained as a biomarker in the cream. To determine the A7OG content present in the cream formulation, liquid–liquid extraction using dichlormethane was applied. In addition, the volume ...
Source: Molecules - January 11, 2023 Category: Chemistry Authors: Jin Seok Lee Yu Ran Nam Hyun Jong Kim Woo Kyung Kim Tags: Article Source Type: research
Molecules, Vol. 28, Pages 158: Therapeutic Potential of Flavonoids and Tannins in Management of Oral Infectious Diseases & mdash;A Review
Molecules, Vol. 28, Pages 158: Therapeutic Potential of Flavonoids and Tannins in Management of Oral Infectious Diseases—A Review
Molecules doi: 10.3390/molecules28010158
Authors:
Ján Kováč
Lívia Slobodníková
Eva Trajčíková
Katarína Rendeková
Pavel Mučaji
Alice Sychrová
Silvia Bittner Fialová
Medicinal plants are rich sources of valuable molecules with various profitable biological effects, including antimicrobial activity. The advantages of herbal products are their effectiveness, relative safety based on research or extended traditional use, and accessibility without prescripti...
Source: Molecules - December 24, 2022 Category: Chemistry Authors: J án Kováč L ívia Slobodníková Eva Traj číková Katar ína Rendeková Pavel Mu čaji Alice Sychrov á Silvia Bittner Fialov á Tags: Review Source Type: research
Agrimol B inhibits colon carcinoma progression by blocking mitochondrial function through the PGC-1 α/NRF1/TFAM signaling pathway
ConclusionsOur findings demonstrated that Agr regulates the expression of PGC-1α, thereby inducing mitochondrial dysfunction and promoting tumor cell apoptosis. This work highlights the potential of Agr as a promising therapeutic candidate in CRC. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - December 14, 2022 Category: Cancer & Oncology Source Type: research
Essential oils of four wild plants inhibit the blood seeking behaviour of female Aedes aegytpi
Exp Parasitol. 2022 Nov 11:108424. doi: 10.1016/j.exppara.2022.108424. Online ahead of print.ABSTRACTAedes aegypti (Diptera: Culicidae) mosquito is an important vector of many disease-causing pathogens. An effective way to escape from these mosquito-borne diseases is to prevent mosquito bites. In the current study, essential oils of Lepidium pinnatifidum, Mentha longifolia, Origanum vulgare, and Agrimonia eupatoria were evaluated for their repellent potential against Ae. aegypti females. Essential oils were extracted using steam distillation from freshly collected aerial parts of the plants and tested against 4-5 day old f...
Source: Experimental Parasitology - November 14, 2022 Category: Parasitology Authors: Sajid Iqbal Fawad Ahmed Khan Abdullah Haris Raimondas Mozuratis Muhammad Binyameen Muhammad Azeem Source Type: research
Essential oils of four wild plants inhibit the blood seeking behaviour of female Aedes aegytpi
Exp Parasitol. 2022 Nov 11:108424. doi: 10.1016/j.exppara.2022.108424. Online ahead of print.ABSTRACTAedes aegypti (Diptera: Culicidae) mosquito is an important vector of many disease-causing pathogens. An effective way to escape from these mosquito-borne diseases is to prevent mosquito bites. In the current study, essential oils of Lepidium pinnatifidum, Mentha longifolia, Origanum vulgare, and Agrimonia eupatoria were evaluated for their repellent potential against Ae. aegypti females. Essential oils were extracted using steam distillation from freshly collected aerial parts of the plants and tested against 4-5 day old f...
Source: Experimental Parasitology - November 14, 2022 Category: Parasitology Authors: Sajid Iqbal Fawad Ahmed Khan Abdullah Haris Raimondas Mozuratis Muhammad Binyameen Muhammad Azeem Source Type: research
Molecules, Vol. 27, Pages 7597: Nutritional and Polyphenolic Composition of Agrimonia procera Wallr. from Experimental Cultivation with Different Levels of Nitrogen Fertilization
osmala
Plants of the genus Agrimonia, including fragrant agrimony Agrimonia procera Wallr., mainly used as pharmaceutical raw material, perfectly fit into the current trends in nutrition and food technology that are searching for organic raw materials with high contents of bioactive compounds, such as dietary polyphenols and fiber. The aim of the research was to determine the nutritional and polyphenolic composition of fragrant agrimony Agrimonia procera Wallr. from experimental cultivation with varying levels of nitrogen fertilization in the nitrate, ammonium, or amide forms. In the experimental cultivation of fragran...
Source: Molecules - November 5, 2022 Category: Chemistry Authors: El żbieta Karlińska Olga Kaczorowska Beata Romanowska Monika Kosmala Tags: Article Source Type: research
Anti-influenza A virus activity by Agrimonia pilosa and Galla rhois extract mixture
In conclusion, APRG64 could be an attractive antiviral drug to treat IAV infection.PMID:36271555 | DOI:10.1016/j.biopha.2022.113773 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 22, 2022 Category: Drugs & Pharmacology Authors: Yong-Hyun Joo Yeong-Geun Lee Younghyun Lim Hoyeon Jeon In-Gu Lee Yong-Bin Cho So-Hee Hong Eui Ho Kim Soon Ho Choi Jung-Woong Kim Se Chan Kang Young-Jin Seo Source Type: research
Anti-influenza A virus activity by Agrimonia pilosa and Galla rhois extract mixture
In conclusion, APRG64 could be an attractive antiviral drug to treat IAV infection.PMID:36271555 | DOI:10.1016/j.biopha.2022.113773 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 22, 2022 Category: Drugs & Pharmacology Authors: Yong-Hyun Joo Yeong-Geun Lee Younghyun Lim Hoyeon Jeon In-Gu Lee Yong-Bin Cho So-Hee Hong Eui Ho Kim Soon Ho Choi Jung-Woong Kim Se Chan Kang Young-Jin Seo Source Type: research
The Medicinal Plant Agrimonia pilosa Ledeb.: Botanical Description, Traditional Use, Phytochemistry and Pharmacology
CONCLUSION: In vitro and in vivo results also successfully explained the pharmacological mechanisms of A. pilosa constituents. More bioassay-guided phytochemical and clinical studies are necessary.PMID:36177633 | DOI:10.2174/1386207325666220928163930 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - September 30, 2022 Category: Chemistry Authors: Nguyen Quang Hop Ninh The Son Source Type: research
The Medicinal Plant Agrimonia pilosa Ledeb.: Botanical Description, Traditional Use, Phytochemistry and Pharmacology
CONCLUSION: In vitro and in vivo results also successfully explained the pharmacological mechanisms of A. pilosa constituents. More bioassay-guided phytochemical and clinical studies are necessary.PMID:36177633 | DOI:10.2174/1386207325666220928163930 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - September 30, 2022 Category: Chemistry Authors: Nguyen Quang Hop Ninh The Son Source Type: research
The Medicinal Plant Agrimonia pilosa Ledeb.: Botanical Description, Traditional Use, Phytochemistry and Pharmacology
CONCLUSION: In vitro and in vivo results also successfully explained the pharmacological mechanisms of A. pilosa constituents. More bioassay-guided phytochemical and clinical studies are necessary.PMID:36177633 | DOI:10.2174/1386207325666220928163930 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - September 30, 2022 Category: Chemistry Authors: Nguyen Quang Hop Ninh The Son Source Type: research
The Medicinal Plant Agrimonia pilosa Ledeb.: Botanical Description, Traditional Use, Phytochemistry and Pharmacology
CONCLUSION: In vitro and in vivo results also successfully explained the pharmacological mechanisms of A. pilosa constituents. More bioassay-guided phytochemical and clinical studies are necessary.PMID:36177633 | DOI:10.2174/1386207325666220928163930 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - September 30, 2022 Category: Chemistry Authors: Nguyen Quang Hop Ninh The Son Source Type: research
The Medicinal Plant Agrimonia pilosa Ledeb.: Botanical Description, Traditional Use, Phytochemistry and Pharmacology
CONCLUSION: In vitro and in vivo results also successfully explained the pharmacological mechanisms of A. pilosa constituents. More bioassay-guided phytochemical and clinical studies are necessary.PMID:36177633 | DOI:10.2174/1386207325666220928163930 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - September 30, 2022 Category: Chemistry Authors: Nguyen Quang Hop Ninh The Son Source Type: research
Proteomics Analysis of Antitumor Activity of < em > Agrimonia pilosa < /em > Ledeb. in Human Oral Squamous Cell Carcinoma Cells
In this study, we used proteomic technology to observe changes in proteins related to anticancer activity of A. pilosa Ledeb. and identified target proteins among altered proteins to reveal the underlying mechanism of action.PMID:35892715 | DOI:10.3390/cimb44080229 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - July 27, 2022 Category: Molecular Biology Authors: Tae-Young Kim Kwang-Soo Koh Ji-Min Ju Yeon-Ju Kwak Soo-Kyung Bae Hye-Ock Jang Da-Sol Kim Source Type: research
