Radiologists distinguish COVID-19 pneumonia on CT
The novel coronavirus disease (COVID-19) is characterized by CT findings that...Read more on AuntMinnie.comRelated Reading: CT findings for coronavirus may overlap with adenovirus How does COVID-19 differ from other coronaviruses? What do radiologists need to know about the coronavirus? CT again tops DNA tests for early coronavirus detection CT proves vital for early diagnosis of COVID-19 (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 12, 2020 Category: Radiology Source Type: news

ACR recommends sparing use of CT for COVID-19
CT should not be used as a first-line diagnostic or screening tool for the...Read more on AuntMinnie.comRelated Reading: 3 factors linked to risk of death from coronavirus CT findings for coronavirus may overlap with adenovirus WHO ups coronavirus mortality rate to 3.4% How does COVID-19 differ from other coronaviruses? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 12, 2020 Category: Radiology Source Type: news

3 factors linked to risk of death from coronavirus
For individuals with the novel coronavirus disease, several factors were associated...Read more on AuntMinnie.comRelated Reading: CT findings for coronavirus may overlap with adenovirus 4 imaging features that define severe COVID-19 X-ray may be missing COVID cases found with CT CT again tops DNA tests for early coronavirus detection How can radiology help limit COVID-19 transmission? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 11, 2020 Category: Radiology Source Type: news

CT findings for coronavirus may overlap with adenovirus
Chest CT accurately detected the novel coronavirus disease (COVID-19) in the...Read more on AuntMinnie.comRelated Reading: How does COVID-19 differ from other coronaviruses? What do radiologists need to know about the coronavirus? CT again tops DNA tests for early coronavirus detection How can radiology help limit COVID-19 transmission? Coronavirus toll surges after sanction of CT diagnosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 10, 2020 Category: Radiology Source Type: news

A Perfect Storm of Uncommon Pathogens in an Immunocompetent Host: Respiratory Isolation of Cunninghamella Berrhotheliae, Aspergillus Niger, Staphylococcus Pseudintermedius and Adenovirus in a Patient with Necrotizing Pneumonia
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

European Medicines Agency Grants PRIME and Advanced Therapy Medicinal Product Designations to Janssen ’s RPGR Gene Therapy for X-Linked Retinitis Pigmentosa
RARITAN, NJ, March 2, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the European Medicines Agency (EMA) has granted both PRIME (PRIority MEdicines) and Advanced Therapy Medicinal Product (ATMP) designations to the company’s adeno-associated virus (AAV)-RPGR gene therapy product for the treatment of inherited retinal disease X-linked retinitis pigmentosa (XLRP). PRIME is awarded to increase interactions, optimize development plans and accelerate innovative treatments where there is unmet medical need. Similarly, ATMP status is granted to medicines that are based on genes, tiss...
Source: Johnson and Johnson - March 2, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Mesothelioma Gene Therapy Trial Shows ‘Real Potential’
Gene therapy is moving closer to becoming part of standard-of-care treatment for pleural mesothelioma, according to the latest multicenter clinical trial. The phase III trial, known as the INFINITE clinical research study, is designed to evaluate the intrapleural delivery of an investigational drug — a type of gene therapy — in combination with celecoxib and gemcitabine, anti-inflammatory and chemotherapy drugs, respectively. Researchers hope to stop, or at least slow, the growth of mesothelioma tumor cells with the combination therapy. “This is a very interesting concept,” oncologist Dr. Bernardo Goulart of the Se...
Source: Asbestos and Mesothelioma News - February 17, 2020 Category: Environmental Health Authors: Matt Mauney Source Type: news

Gene Therapy for Mesothelioma Has ‘Real Potential’
Gene therapy is moving closer to becoming part of standard-of-care treatment for pleural mesothelioma, according to the latest multicenter clinical trial. The phase III trial, known as the INFINITE clinical research study, is designed to evaluate the intrapleural delivery of an investigational drug — a type of gene therapy — in combination with celecoxib and gemcitabine, anti-inflammatory and chemotherapy drugs, respectively. Researchers hope to stop, or at least slow, the growth of mesothelioma tumor cells with the combination therapy. “This is a very interesting concept,” oncologist Dr. Bernardo Goulart of the Se...
Source: Asbestos and Mesothelioma News - February 17, 2020 Category: Environmental Health Authors: Matt Mauney Source Type: news

Researchers uncover mechanism for how common gene therapy vectors enter cells
(Massachusetts Eye and Ear Infirmary) Researchers have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types -- the most commonly used viral vectors for in vivo gene therapy. The researchers identified that GPR108, a G protein-coupled receptor, served as a molecular 'lock' to the cell. The discovery could one day enable scientists to better direct AAV gene transfers to specific tissues. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 23, 2020 Category: Biology Source Type: news

What Is the Classic Clinical Presentation of Pericarditis?
Discussion The pericardium is a bi-layered membrane that envelops the heart and provides a barrier to prevent disease and also decreases friction as the heart moves. Pericarditis is the inflammation of pericardium. The incidence is underreported as asymptomatic or mild disease may go unrecognized. From hospitalized patient data, 0.2-5% of patients with various cardiac disease had pericarditis. An incidence rate for hospitalizations of 3.32 per 100,000 person years has been cited. Percarditis occurs more often in adolescent males. Treatment of the underlying cause or suspected cause is important, along with close monitorin...
Source: PediatricEducation.org - January 13, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Symptomatic Respiratory Syncytial Virus and Adenovirus Upper Respiratory Tract Infections Increase the Risk of Invasive Aspergillosis After Allogeneic Hematopoietic Cell Transplantation
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 30, 2019 Category: Respiratory Medicine Authors: MeganB Source Type: news

Newly discovered protein gives signal for virus infection
(University of Zurich) Researchers at the University of Zurich have discovered a protein that enables adenoviruses to infect human cells. The Mib1 protein gives the virus the signal to uncoat the DNA and release it into the nucleus. Blocking this protein could therefore help people with weakened immune systems to fight dangerous viruses. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 17, 2019 Category: Infectious Diseases Source Type: news

Adenovirus Outbreak Affects 3 University Of Wisconsin Campuses, What Is This Virus?
Something is going viral on three University of Wisconsin campuses, and it isn ’t a pretty picture. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 7, 2019 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

DHS Investigates Outbreak of Adenovirus Infections on College Campuses
The Wisconsin Department of Health Services is investigatingmultiple cases of adenovirus (add-e-no-virus) infectionon college campuses around the state. Adenovirus infections most commonly cause respiratory illness, and while serious illness is rare, in some cases it can lead to pneumonia or death. “Adenovirus infection is easily spread, which is why we tend to see it in places where large groups gather, like college dormitories and classrooms,” said...(see release) (Source: Wisconsin DHFS Press Releases)
Source: Wisconsin DHFS Press Releases - December 4, 2019 Category: Hospital Management Authors: millejcodn Source Type: news

Unexpected viral behavior linked to type 1 diabetes in high-risk children
(University of South Florida (USF Health)) New results from the Environmental Determinants of Diabetes in the Young (TEDDY) study show an association between prolonged enterovirus infection and development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes. Conversely, adenovirus C infection seems to confer protection from autoimmunity. The international research suggests new therapeutic avenues for prevention in some children. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 2, 2019 Category: Infectious Diseases Source Type: news