Exploiting viruses to attack cancer cells
(Hokkaido University) Hokkaido University scientists have made an adenovirus that specifically replicates inside and kills cancer cells by employing special RNA-stabilizing elements. The details of the research were published in the journal Cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 28, 2020 Category: Cancer & Oncology Source Type: news

Adenovirus Type - 5 Vectored COVID - 19 Vaccine Shows Promise
ELISA antibodies and neutralizing antibodies increased at day 14, peaked at day 28 (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - May 26, 2020 Category: Respiratory Medicine Tags: Family Medicine, Infections, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pathology, Pharmacy, Pulmonology, Journal, Source Type: news

Adenovirus Type-5 Vectored COVID-19 Vaccine Shows Promise
TUESDAY, May 26, 2020 -- A recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine is safe, tolerable, and immunogenic, according to a study published online May 22 in The Lancet. Feng-Cai Zhu, Ph.D., from the Jiangsu Provincial Center for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 26, 2020 Category: Pharmaceuticals Source Type: news

Two Boston Hospitals Team Up In ‘Urgent’ Race To Create Coronavirus Vaccine
BOSTON (CBS) – Two Boston hospitals are teaming up in the race to find a cure for the coronavirus pandemic. Researchers at Massachusetts Eye and Ear and Massachusetts General Hospital are working together to develop a vaccine using a unique gene-based strategy. Their research is using what’s called AAV technology, or Adeno-Associated-Virus technology, in hopes of stimulating the immune system to fight SARS-CoV-2 – the virus responsible for COVID-19. “We’re taking a virus called AAV, that’s harmless and has been engineered to be harmless, and we’re using it essentially as a delivery vehicle,” explained K...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 5, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Coronavirus Mass Eye And Ear Mass General Hospital Source Type: news

Massachusetts Eye and Ear, Mass General advancing novel gene-based COVID-19 vaccine, AAVCOVID
(Massachusetts Eye and Ear Infirmary) A unique COVID-19 genetic vaccine program is underway with Mass. Eye and Ear and Mass General Hospital, member hospitals of Mass General Brigham. The AAVCOVID vaccine program is the only gene-based vaccine approach for COVID-19 that uses adeno-associated virus (AAV), a harmless viral vector, as a delivery vehicle for inducing an immune response. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 5, 2020 Category: Infectious Diseases Source Type: news

High-resolution CT improves pulmonary nodule evaluation
Japanese researchers have found that boosting the matrix size for high-resolution...Read more on AuntMinnie.comRelated Reading: AI aids classification of indeterminate lung nodules Panel: CT lung screening can be delayed during COVID-19 CT findings for coronavirus may overlap with adenovirus X-ray may be missing COVID-19 cases found with CT Risk model predicts malignancy of lung nodules on CT (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 4, 2020 Category: Radiology Source Type: news

AstraZeneca and Oxford University announce landmark agreement for COVID-19 vaccine
AstraZeneca and the University of Oxford announced an agreement for the global development and distribution of the University’s potential recombinant adenovirus vaccine aimed at preventing COVID-19 infection from SARS-CoV-2. The collaboration aims to bring to patients the potential vaccine known as ChAdOx1 nCoV-19, being developed by the Jenner Institute and Oxford Vaccine Group, at the University of Oxford. (Source: World Pharma News)
Source: World Pharma News - April 30, 2020 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

Oxford COVID-19 vaccine programme opens for clinical trial recruitment
University of Oxford researchers working in an unprecedented vaccine development effort to prevent COVID-19 have started screening healthy volunteers (aged 18-55) for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein is already in production but won’t be ready for some weeks still. (Source: World Pharma News)
Source: World Pharma News - April 21, 2020 Category: Pharmaceuticals Tags: Featured Development Research and Development Source Type: news

Investigational chimp adenovirus MERS-CoV vaccine protects monkeys
Vaccine neutralizes multiple MERS-CoV strains. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 17, 2020 Category: American Health Source Type: news

Imaging confirms coronavirus transmits from mother to fetus
The combination of CT, x-ray, and DNA testing confirmed that the novel coronavirus...Read more on AuntMinnie.comRelated Reading: CT details effect of COVID-19 on pregnant women CT depicts how COVID-19 abnormalities change over time CT illuminates COVID-19 in Diamond Princess cases Radiologists distinguish COVID-19 pneumonia on CT CT findings for coronavirus may overlap with adenovirus (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 26, 2020 Category: Radiology Source Type: news

CT depicts how COVID-19 abnormalities change over time
CT scans revealed rapid progression of abnormalities in COVID-19 patients,...Read more on AuntMinnie.comRelated Reading: CT details effect of COVID-19 on pregnant women CT illuminates COVID-19 in Diamond Princess cases 3 factors linked to risk of death from coronavirus Radiologists distinguish COVID-19 pneumonia on CT CT findings for coronavirus may overlap with adenovirus (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 20, 2020 Category: Radiology Source Type: news

CT details effect of COVID-19 on pregnant women
Does COVID-19 have a more devastating effect on pregnant women? Is the disease...Read more on AuntMinnie.comRelated Reading: Ultrasound can be used for patients with COVID-19 CT illuminates COVID-19 in Diamond Princess cases 3 factors linked to risk of death from coronavirus Radiologists distinguish COVID-19 pneumonia on CT CT findings for coronavirus may overlap with adenovirus (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 20, 2020 Category: Radiology Source Type: news

Tracking adeno-associated virus capsid evolution
(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers have used high-throughput screening of adeno-associated viral (AAV) vector capsid libraries to maximize the likelihood of obtaining AAV variants with desired properties. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 18, 2020 Category: International Medicine & Public Health Source Type: news

CT shows pneumonia patterns in kids with coronavirus
CT helped confirm that the novel coronavirus disease is indeed capable of triggering...Read more on AuntMinnie.comRelated Reading: 3 factors linked to risk of death from coronavirus CT findings for coronavirus may overlap with adenovirus How does COVID-19 differ from other coronaviruses? What do radiologists need to know about the coronavirus? CT again tops DNA tests for early coronavirus detection (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 12, 2020 Category: Radiology Source Type: news

Study outlines 1st person-to-person coronavirus spread
A study published March 12 in the Lancet journal describes what is...Read more on AuntMinnie.comRelated Reading: 3 factors linked to risk of death from coronavirus Radiologists distinguish COVID-19 pneumonia on CT USARad offers COVID-19 screening program ACR recommends sparing use of CT for COVID-19 CT findings for coronavirus may overlap with adenovirus (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 12, 2020 Category: Radiology Source Type: news