VARGADO data
Vargatef ® plus docetaxel could be an option after failure of immunotherapy in lung cancerResults from a real-world study1 support a recent update to the ESMO guidelines2 recommending nintedanib (Vargatef®) plus docetaxel following first-line chemotherapy (+/- immunotherapy) in advanced NSCLC of adenocarcinoma histology (Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - December 13, 2018 Category: Research Source Type: news
Intraoperative Consultation on Surgical Margins 98% Accurate in Gastric Cancer Intraoperative Consultation on Surgical Margins 98% Accurate in Gastric Cancer
The false-negative rate of intraoperative consultation (IOC) on surgical margins during resection of gastric and gastroesophageal adenocarcinoma is less than 2% overall, according to a retrospective study at a specialty center.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - November 6, 2018 Category: Surgery Tags: Hematology-Oncology News Source Type: news
Pancreatic cancer genetic marker may predict outcomes with radiation therapy
(Thomas Jefferson University) scientists find that a gene involved in the immune system called IDO2 plays a significant role in pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The discovery may help physicians provide better treatment options for patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 22, 2018 Category: Cancer & Oncology Source Type: news
Short-term ADT with RT improves survival over RT alone up to 10 years
(NRG Oncology) The long-term follow up of the NRG Oncology trial RTOG 9408, studying the addition of short-term androgen-deprivation therapy (ADT) to radiotherapy (RT) for men with early, localized prostate adenocarcinoma, indicated that RT combined with ADT is superior to RT alone for overall survival (OS) up to 10.4 years following treatment. However, when researchers assessed these results up to 18 years, the benefits of adding ADT to RT dissipated. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 22, 2018 Category: International Medicine & Public Health Source Type: news
Increased survival in patients with metastatic NSCLC receiving treatment in academic centers
(International Association for the Study of Lung Cancer) Patients with metastatic NSCLC receiving treatment at academic centers (ACs) have an increased 2-year survival compared to patients treated at community-based centers (CCs). An overall histology-dependent survival was also noted in patients with adenocarcinoma verses squamous cell carcinoma and varied by treatment facility. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 10, 2018 Category: Cancer & Oncology Source Type: news
UCLA researchers discover aggressive prostate and lung cancers are driven by common mechanisms
UCLA researchers have discovered a common process in the development of late-stage, small cell cancers of the prostate and lung. These shared molecular mechanisms could lead to the development of drugs to treat not just prostate and lung cancers, but small cell cancers of almost any organ.The key finding: Prostate and lung cells have very different patterns of gene expression when they ’re healthy, but almost identical patterns when they transform into small cell cancers. The research suggests that different types of small cell tumors evolve similarly, even when they come from different organs.The study, led by Dr. Owen ...
Source: UCLA Newsroom: Health Sciences - October 4, 2018 Category: Universities & Medical Training Source Type: news
Nano-Optic Endoscope Offers Anatomic Pathologists, Medical Laboratories Higher Resolution and Precision Optical Imaging
New metalens technology from MGH and SEAS researchers gives greater endoscopic optical imaging resolution and sample detail for anatomic pathologists performing diagnostics Anatomic pathologists and clinical laboratories know that biopsy samples are necessary to diagnose many diseases. But, current endoscopic imaging techniques used by physicians sometimes fail to clearly visualize disease sites. Consequently, biopsies collected […] (Source: Dark Daily)
Source: Dark Daily - September 26, 2018 Category: Laboratory Medicine Authors: Jude Tags: Instruments & Equipment Laboratory Instruments & Laboratory Equipment Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations adenocarcinoma anatomic path Source Type: news
Is AI the Key to Diving Deeper into Images and Pathology?
In a tale of two studies, it appears artificial intelligence is helping researchers analyze cells in ways that weren't possible before.
In one study, published this week in Nature Methods, scientists at the Allen Institute in Seattle, WA used machine learning to train computers to see parts of the cell that the human eye cannot easily distinguish. Using 3D images of fluorescently labeled cells, the team taught computers to find structures inside living cells without fluorescent labels, using only black and white images generated by an inexpensive technique known as brightfield microscopy.
Fluorescence microscop...
Source: MDDI - September 19, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Imaging Source Type: news
Reducing Risk of Esophageal Cancer in Barrett's Esophagus Reducing Risk of Esophageal Cancer in Barrett's Esophagus
Patients with Barrett ' s esophagus have a high risk of developing esophageal adenocarcinoma. Can PPIs and H2 receptor antagonists mitigate the risk?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 18, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Circulating Tumor Cell Dynamics in Pancreatic Adenocarcinoma Circulating Tumor Cell Dynamics in Pancreatic Adenocarcinoma
What is the clinical significance of circulating tumor cells in pancreatic ductal adenocarcinoma?Annals of Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 10, 2018 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news
Barrett's Tied to Better Survival in Esophageal Ca
(MedPage Today) -- Data suggests existence of two distinct types of esophageal adenocarcinoma (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 6, 2018 Category: Gastroenterology Source Type: news
Endocervical Cells With Gastric-Type Mucin on Pap Smears Endocervical Cells With Gastric-Type Mucin on Pap Smears
Does gastric-type mucin observed on Pap smears provide diagnostic value for endocervical adenocarcinoma and its precursors?American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 4, 2018 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news
Could HPV Be Prognostic in Esophageal Cancer Too? Could HPV Be Prognostic in Esophageal Cancer Too?
HPV positivity is associated with significantly better outcomes in patients with Barrett ' s high-grade dysplasia or esophageal adenocarcinoma, suggesting less intensive therapy might be considered.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 3, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Post-Prostatectomy Radiation Therapy: Patient Selection, Timing, Imaging, and Therapy Intensification
A 62-year-old man with prostate adenocarcinoma elected to proceed with radical prostatectomy as definitive management. After his pathology report showed stage IIIB disease, he elected for observation. What happened next? (Source: CancerNetwork)
Source: CancerNetwork - July 18, 2018 Category: Cancer & Oncology Authors: Tyler P. Robin, MD, PhD, Paul D. Maroni, MD, Bennett B. Chin, MD, Francisco G. La Rosa, MD, Brandon Bernard, MD, MPH, Thomas J. Pugh, MD Source Type: news
Complex Glandular Patterns in Lung Adenocarcinoma Complex Glandular Patterns in Lung Adenocarcinoma
This study provides new insight into the potential role of complex glandular patterns in clinical management of lung adenocarcinoma.American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 10, 2018 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news
