Effects of half-dose spiomet treatment in girls with early puberty and accelerated bone maturation: a multicenter, randomized, placebo-controlled study protocol
DiscussionThe present study, if successful, may provide a first proof of the concept that the rapid maturation of girls with an upward mismatch between pre- and post-natal weight gain can be slowed down with a fixed low-dose combination of old and safe generics jointly targeting a reduction of ectopic fat without necessarily lowering body weight.Trial registrationEudraCT 2021-006766-21. Registered on May 30, 2022. (Source: Trials)
Source: Trials - January 24, 2023 Category: Research Source Type: clinical trials

Effect of Acarbose and Mixture of Pioglitazone and Metformin in Patients With Type 2 Diabetes
Conditions:   Type 2 Diabetes;   Blood Glucose Fluctuation Interventions:   Drug: Metformin plus pioglitazone;   Drug: Acarbose Sponsor:   Nanjing First Hospital, Nanjing Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 29, 2022 Category: Research Source Type: clinical trials

Comparative Clinical Study Between Empagliflozin Versus Pioglitazone in Non-diabetic Patients With Non-alcoholic Steatohepatitis
Condition:   Non Alcoholic Steatohepatitis Interventions:   Drug: Pioglitazone 30mg;   Drug: Empagliflozin 10 MG Sponsor:   Tanta University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 4, 2022 Category: Research Source Type: clinical trials