MKSAP: 71-year-old man with new dyspnea on exertion
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.A 71-year-old man is evaluated in the emergency department for new dyspnea on exertion. He has a 15-year history of type 2 diabetes mellitus and has had a number of changes in his medications over the past 12 weeks to improve glycemic control. His dosage of metformin has been increased to 1000 mg/d, glyburide to 10 mg/d, and pioglitazone to 45 mg/d. Within the past week, bedtime insulin glargine was initiated.On physical examination, blood pressure is 140/90 mm Hg, pulse rate is 90/min, and respiration rate is 20/...
Source: Kevin, M.D. - Medical Weblog - January 27, 2013 Category: Family Physicians Tags: Meds Diabetes Heart Source Type: blogs
10 Reasons Why The Actos Pre-Diabetes Study is Dumb
A week ago, the media was all abuzz about a new study published in the New England Journal of Medicine showing that the oral drug Actos can prevent diabetes. At first we at the 'Mine didn't pay much attention, because of course we're more concerne... (Source: Diabetes Mine)
Source: Diabetes Mine - April 1, 2011 Category: Endocrinology Authors: Amy Tenderich Source Type: blogs
Insulin v. Triple oral therapy for DM
Diabetes Care 12/23/09 – “Insulin is the most effective hypoglycemic agent in our treatment armamentarium and is now recommended by the American Diabetes Association (ADA) guidelines as the second agent added after metformin” (FTA). Despite this fact (or because some of us were unaware of this guideline), physicians often prefer to max out that second and third oral medication before turning to insulin. An article in Diabetes Care looks at a comparison between a three drug regimen and insulin + metformin for newly diagnosed DM.
The study compared 2 groups of 29 subjects that were newly diagnosed diabe...
Source: Consider The Evidence: Med/Peds Journal Roundup - January 3, 2010 Category: Internists and Doctors of Medicine Authors: medblog Tags: diabetes Source Type: blogs
