SCCM Pod-504 CCM: Baricitinib or Tocilizumab for Severe COVID-19
Host Marilyn N. Bulloch, PharmD, BCPS, FCCM, is joined by Joy Peterson, PharmD, BCPS, BCIDP, Neha Paranjape, MD, MPH, to discuss the article, "Outcomes and Adverse Effects of Baricitinib Versus Tocilizumab in the Management of Severe COVID-19," (Crit Care Med. March 2023 51(3):337-346) which delves into the comparative outcomes, mortality rates, and adverse effects of baricitinib and tocilizumab in severe COVID-19 cases. Dr. Peterson is a Clinical Pharmacy Specialist in infectious disease, and Dr. Paranjape is an Infectious Disease Specialist at Wellstar Health System in Marietta, Georgia. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - March 25, 2024 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
TWiV 970: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses modelling the adjustment of COVID-19 response and exit from dynamic zero-COVID in China, canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event, two masks can be worse than one: N95 respirator failure caused by an overlying face mask, airflow patterns in double-occupancy patient rooms may contribute to roommate-to-roommate transmission of severe SARS-CoV-2, clinical validation of a novel T-Cell receptor sequencing assay for identification of recent or prior SARS-CoV-2 infection, antibody-dependent cellular cytotoxicity against SARS-...
Source: This Week in Virology - MP3 Edition - December 31, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: This Week in Virology - MP3 Edition - October 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Tocilizumab for Polymyalgia Rheumatica, Helmet Noninvasive Ventilation for Severe COVID-19, Roflumilast Cream for Chronic Plaque Psoriasis, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the September 20, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - September 20, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts
TWiV 934: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses variant influenza virus infections: recommendations for identification, treatment, and prevention for summer and fall 2022, low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals, using the right tools at the right time for SARS-COV-2 infection, onset and window of SARS-COV-2 infectiousness and temporal correlation with symptom onset, transmission of SARS-COV-2: a review of viral, host, and environmental factors, antibody persistence and safety through 6 months after heterologous orally aerosolized Ad5-nCoV in individuals...
Source: This Week in Virology - MP3 Edition - September 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 886: COVID-19 clinical update #109 with Dr. Daniel Griffin
In COVID-19 clinical update #109, Daniel Griffin discusses cardiac complications after infection or vaccination, long COVID in children, fourth vaccine dose in Israel, no need for fourth vaccine does in EU, dexamethasone dosing, immunomodulation therapy, MIS outcomes in children, US long COVID effort launched, and herd immunity. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cardiac complications after infection or vaccination (MMWR) Long COVID in children (Future Med) Fourth vaccine dose in Israel (NEJM) No need for fourth vaccine dose (Eur Med Agency)...
Source: This Week in Virology - MP3 Edition - April 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 856: COVID-19 clinical update #98 with Dr. Daniel Griffin
In COVID-19 clinical update #98, Daniel Griffin reviews COVID-19 in South Africa, recognition of Omicron by ancestral T cells, booster effectiveness against disease, infection and vaccination in pregnant women, early Remdesivir to prevent progression to severe disease, management of hospitalized adults, Tocilizumab in hospitalized patients, vaccination and long COVID, and the true toll of the pandemic. Click arrow to play Download TWiV 853 (58 MB .mp3, 48 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 in South Africa (pdf) Ancestral T cells recogn...
Source: This Week in Virology - MP3 Edition - January 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 826: COVID-19 clinical update #87 with Dr. Daniel Griffin
In COVID-19 clinical update #87, Dr. Griffin reviews PCR cycle threshold and RNA copy number, rapid antigen tests, hospitalization rate after infection or vaccination, allergies and vaccination, community transmission and viral RNA load, early treatment with sotrovimab, meta-analysis of tocilizumab treatment, antibiotic overuse, and guidelines on the use of anticoagulation for thromboprophylaxis. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC vaccine nod to 5-11 year olds (CDC) Sensitivity of rapid antigen tests ...
Source: This Week in Virology - MP3 Edition - November 6, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 811: COVID-19 clinical update #82 with Dr. Daniel Griffin
In COVID-19 clinical update #82, Daniel Griffin reviews vaccines for 5-12 years old, safety of a third vaccine dose, Oklahoma reinfection data, Regencov outcomes, Pfizer protease inhibitor, impact of Tocilizumab, and incidence of long COVID. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Data on Pfizer-BioNTech in 5-12 year olds (Pfizer) Safety of additional vaccine dose (MMWR) Oklahoma reinfection rates (OK DOH) Regencov outcomes (NEJM) Pfizer protease inhibitor trial (Pfizer) WHO recommends antibody therapy (Hosp H...
Source: This Week in Virology - MP3 Edition - October 2, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 775: COVID-19 clinical update #69 with Dr. Daniel Griffin
In COVID-19 clinical update #69, Daniel Griffin covers effectiveness of mRNA vaccines against the delta variant, depression among public health workers, correlates of protection against asymptomatic and symptomatic infection, BNT162b2 in ChAdOx-1-S primed individuals, prior infection rescues B and T cell responses to variants after vaccination, effect of vaccination on household transmission, germinal responses induced by mRNA vaccines, phase 3 results of Novavax vaccine, and long COVID as our next national health disaster. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, e...
Source: This Week in Virology - MP3 Edition - July 3, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 752: COVID-19 clinical update #61 with Dr. Daniel Griffin
In COVID-19 clinical update #61, Daniel Griffin reviews a modeling of future hospitalizations and deaths by vaccination rates and non pharmaceutical intervention scenarios, performance evaluation of rapid antigen tests, children making up a growing share of new cases, antibody response to mRNA vaccine in solid organ transplant recipients, and outcomes in hospitalized patients treated with tocilizumab. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Modeling future COVID-19 cases (MMWR) Performance of rapid antigen tes...
Source: This Week in Virology - MP3 Edition - May 8, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
