TWiV 886: COVID-19 clinical update #109 with Dr. Daniel Griffin
In COVID-19 clinical update #109, Daniel Griffin discusses cardiac complications after infection or vaccination, long COVID in children, fourth vaccine dose in Israel, no need for fourth vaccine does in EU, dexamethasone dosing, immunomodulation therapy, MIS outcomes in children, US long COVID effort launched, and herd immunity. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cardiac complications after infection or vaccination (MMWR) Long COVID in children (Future Med) Fourth vaccine dose in Israel (NEJM) No need for fourth vaccine dose (Eur Med Agency)...
Source: This Week in Virology - MP3 Edition - April 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 856: COVID-19 clinical update #98 with Dr. Daniel Griffin
In COVID-19 clinical update #98, Daniel Griffin reviews COVID-19 in South Africa, recognition of Omicron by ancestral T cells, booster effectiveness against disease, infection and vaccination in pregnant women, early Remdesivir to prevent progression to severe disease, management of hospitalized adults, Tocilizumab in hospitalized patients, vaccination and long COVID, and the true toll of the pandemic. Click arrow to play Download TWiV 853 (58 MB .mp3, 48 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 in South Africa (pdf) Ancestral T cells recogn...
Source: This Week in Virology - MP3 Edition - January 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 826: COVID-19 clinical update #87 with Dr. Daniel Griffin
In COVID-19 clinical update #87, Dr. Griffin reviews PCR cycle threshold and RNA copy number, rapid antigen tests, hospitalization rate after infection or vaccination, allergies and vaccination, community transmission and viral RNA load, early treatment with sotrovimab, meta-analysis of tocilizumab treatment, antibiotic overuse, and guidelines on the use of anticoagulation for thromboprophylaxis. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC vaccine nod to 5-11 year olds (CDC) Sensitivity of rapid antigen tests ...
Source: This Week in Virology - MP3 Edition - November 6, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 811: COVID-19 clinical update #82 with Dr. Daniel Griffin
In COVID-19 clinical update #82, Daniel Griffin reviews vaccines for 5-12 years old, safety of a third vaccine dose, Oklahoma reinfection data, Regencov outcomes, Pfizer protease inhibitor, impact of Tocilizumab, and incidence of long COVID. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Data on Pfizer-BioNTech in 5-12 year olds (Pfizer) Safety of additional vaccine dose (MMWR) Oklahoma reinfection rates (OK DOH) Regencov outcomes (NEJM) Pfizer protease inhibitor trial (Pfizer) WHO recommends antibody therapy (Hosp H...
Source: This Week in Virology - MP3 Edition - October 2, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 775: COVID-19 clinical update #69 with Dr. Daniel Griffin
In COVID-19 clinical update #69, Daniel Griffin covers effectiveness of mRNA vaccines against the delta variant, depression among public health workers, correlates of protection against asymptomatic and symptomatic infection, BNT162b2 in ChAdOx-1-S primed individuals, prior infection rescues B and T cell responses to variants after vaccination, effect of vaccination on household transmission, germinal responses induced by mRNA vaccines, phase 3 results of Novavax vaccine, and long COVID as our next national health disaster. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, e...
Source: This Week in Virology - MP3 Edition - July 3, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 752: COVID-19 clinical update #61 with Dr. Daniel Griffin
In COVID-19 clinical update #61, Daniel Griffin reviews a modeling of future hospitalizations and deaths by vaccination rates and non pharmaceutical intervention scenarios, performance evaluation of rapid antigen tests, children making up a growing share of new cases, antibody response to mRNA vaccine in solid organ transplant recipients, and outcomes in hospitalized patients treated with tocilizumab. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Modeling future COVID-19 cases (MMWR) Performance of rapid antigen tes...
Source: This Week in Virology - MP3 Edition - May 8, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 727: COVID-19 clinical update #52 with Dr. Daniel Griffin
In COVID-19 clinical update #52, Daniel Griffin reviews differences in attack rates between children and adults, J&J vaccine phase III data, G6PD deficiency and vaccines, NIH halts convalescent plasma trial, dexamethasone in hospitalized patients, data on tocilizumab, and long COVID in children. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode SARS-CoV-2 attack rates in children and adults (Clin Inf Dis) Documents for J&J COVID-19 vaccine review (FDA) Convalescent plasma and clinical outcomes (JAMA) NIH halts convalesc...
Source: This Week in Virology - MP3 Edition - March 6, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 719: COVID-19 clinical update #49 with Dr. Daniel Griffin
In COVID-19 clinical update #49, Daniel Griffin discusses CDC guidelines on mask use, drop in test frequency in the US, resurgence of COVID-19 in Brazil, possible impact of Pfizer vaccine on viral load, EUA for bamlanivimab and etesevimab administered together, and preliminary results of Tocilizumab in hospitalized patients. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Resurgence of COVID-19 in Brazil (Lancet) Pfizer vaccine reduces viral load (medRxiv) EUA for bamlanivimab plus etesevimab (pdf) Tocilizumab in hos...
Source: This Week in Virology - MP3 Edition - February 13, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 671: Prizes, polio, and a pandemic puzzle
Daniel Griffin provides a clinical report on COVID-19, then Amy joins us to discuss the 2020 Chemistry Nobel Prize for gene editing using CRISPR/Cas9, continuing circulation of poliovirus in Afghanistan, inborn errors of interferon in patients with severe COVID-19, and listener questions. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Guests: Daniel Griffin and Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASH guidelines on anticoagulants in COVID-19 patients (ASH) Followup of adults with noncritical COVID-19 (Clin Micr Inf) Tocilizumab in...
Source: This Week in Virology - MP3 Edition - October 11, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 648: Life is for learning
Daniel Griffin provides a clinical report on COVID-19, followed by a review of the findings that children shed as much SARS-CoV-2 viral RNA from the respiratory tract as older patients, the lineage giving rise to SARS-CoV-2 has been circulating in bats in China for decades, and answers to listener questions. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Daniel Griffin and Chuck Knirsch Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Roche trial of Actemra for COVID-19 fails (Reuters) Postdoctoral position at RM...
Source: This Week in Virology - MP3 Edition - August 2, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 632: Countering a miasma of anti-think
Daniel Griffin provides a clinical update on COVID-19, then we review SARS-CoV-2 infections in non-humans, vesicular stomatitis in Kansas horses, and answer listener questions. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler and Brianne Barker Guests: Daniel Griffin and Chuck Knirsch Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Dexamethasone for COVID-19 (medRxiv) Proning trial for COVID-19 (Lancet) Tocilizumab for COVID-19 cytokine storm (Chest) Global causes of death Vesicular stomatitis in horses (ProMedMail) Daily tests needed (At...
Source: This Week in Virology - MP3 Edition - June 28, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts