Long-term Depot Specific Changes in Adipose Tissue after Treatment of Acromegaly
CONCLUSION: Treatment of acromegaly leads to an increase in AT mass in a depot and sex specific manner both at short-term and long-term follow-up. Glucose metabolism improves rapidly after disease control and persists.PMID:38401530 | DOI:10.1093/ejendo/lvae016 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - February 24, 2024 Category: Endocrinology Authors: Camilla M Falch Kristin Godang Tove Lekva Thor Ueland Ansgar Heck Jens Bollerslev Nicoleta C Olarescu Source Type: research

Long-term Depot Specific Changes in Adipose Tissue after Treatment of Acromegaly
CONCLUSION: Treatment of acromegaly leads to an increase in AT mass in a depot and sex specific manner both at short-term and long-term follow-up. Glucose metabolism improves rapidly after disease control and persists.PMID:38401530 | DOI:10.1093/ejendo/lvae016 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - February 24, 2024 Category: Endocrinology Authors: Camilla M Falch Kristin Godang Tove Lekva Thor Ueland Ansgar Heck Jens Bollerslev Nicoleta C Olarescu Source Type: research

Tall stature and gigantism in adult patients with acromegaly
CONCLUSION: In a group of 135 consecutive adult patients with acromegaly, 23% had increased height based on country specific and MPH data: 13% presented with gigantism while 10% had TS. The frequency of gigantism and TS in patients diagnosed with GH excess as adults is not higher in males than in females. Patients with acromegaly come from normal-stature families.PMID:38391173 | DOI:10.1093/ejendo/lvae019 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - February 23, 2024 Category: Endocrinology Authors: Anna Bogus ławska Magdalena Godlewska Alicja Hubalewska-Dydejczyk M árta Korbonits Jerzy Starzyk Aleksandra Gilis-Januszewska Source Type: research

Tall stature and gigantism in adult patients with acromegaly
CONCLUSION: In a group of 135 consecutive adult patients with acromegaly, 23% had increased height based on country specific and MPH data: 13% presented with gigantism while 10% had TS. The frequency of gigantism and TS in patients diagnosed with GH excess as adults is not higher in males than in females. Patients with acromegaly come from normal-stature families.PMID:38391173 | DOI:10.1093/ejendo/lvae019 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - February 23, 2024 Category: Endocrinology Authors: Anna Bogus ławska Magdalena Godlewska Alicja Hubalewska-Dydejczyk M árta Korbonits Jerzy Starzyk Aleksandra Gilis-Januszewska Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Drugs & Pharmacology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Endocrinology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Drugs & Pharmacology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Endocrinology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Drugs & Pharmacology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Endocrinology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Drugs & Pharmacology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Endocrinology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Drugs & Pharmacology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

The Effect of Metformin Treatment on Disease Control in Patients with Acromegaly
CONCLUSION: Due to the effect of metformin treatment on insulin-like growth factor-1 values in patients with acromegaly, it can be used in disease control, as well as diabetes treatment.PMID:38379171 | DOI:10.2174/0118715303260084231102105149 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 21, 2024 Category: Endocrinology Authors: Humeyra Rekali Sahin Serdar Sahin Betul Sarac Cem Sulu Pinar Kadioglu Hande Mefkure Ozkaya Source Type: research

High mortality risk among women with acromegaly still persists
ConclusionPatients diagnosed with acromegaly in the last 15 years had lower mortality rates than those diagnosed before 2008, due to the availability of new medications, primarily somatostatin receptor analogs and to a higher proportion of patients undergoing surgery. Females still have a high mortality ratio owing to older age at diagnosis and higher risk of metabolic complications. Therefore, efforts should be made for early diagnosis of acromegaly in women. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - February 21, 2024 Category: Endocrinology Source Type: research