Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study
CONCLUSIONS: gQlab administration can improve the overall IBS symptoms, especially in female and constipation-predominant IBS patients. Further research is necessary to clarify the pathophysiology behind sex-related treatment responses in IBS patients.PMID:38173160 | PMC:PMC10774795 | DOI:10.5056/jnm23036 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - January 4, 2024 Category: Gastroenterology Authors: Young Hoon Chang Yoon Jin Choi Cheol Min Shin Jin Seok Moon Tae-Yoon Kim Hyuk Yoon Young Soo Park Nayoung Kim Dong Ho Lee Source Type: research

Preparation of Synbiotic Yogurt Sauce Containing < em > Spirulina platensis < /em > Microalgae Extract and Its Effect on the Viability of < em > Lactobacillus acidophilus < /em >
Biomed Res Int. 2023 Dec 26;2023:8434865. doi: 10.1155/2023/8434865. eCollection 2023.ABSTRACTBACKGROUND: Preparing a healthy and practical substitute for mayonnaise and reducing the complications caused by its consumption are two of the concerns of the producers of this product. Therefore, this study was conducted with the aim of evaluating the possibility of producing synbiotic yogurt sauce prepared with Spirulina platensis microalgae extract (SPAE) as a valuable and alternative product for mayonnaise.MATERIALS AND METHODS: After preparing yogurt from fresh cow's milk, synbiotic yogurt sauce was prepared according to the...
Source: Biomed Res - January 3, 2024 Category: Research Authors: Hamidreza Kazemeini Asghar Azizian Katayoun Ahmadi Source Type: research

Preparation of Synbiotic Yogurt Sauce Containing < em > Spirulina platensis < /em > Microalgae Extract and Its Effect on the Viability of < em > Lactobacillus acidophilus < /em >
Biomed Res Int. 2023 Dec 26;2023:8434865. doi: 10.1155/2023/8434865. eCollection 2023.ABSTRACTBACKGROUND: Preparing a healthy and practical substitute for mayonnaise and reducing the complications caused by its consumption are two of the concerns of the producers of this product. Therefore, this study was conducted with the aim of evaluating the possibility of producing synbiotic yogurt sauce prepared with Spirulina platensis microalgae extract (SPAE) as a valuable and alternative product for mayonnaise.MATERIALS AND METHODS: After preparing yogurt from fresh cow's milk, synbiotic yogurt sauce was prepared according to the...
Source: Biomed Res - January 3, 2024 Category: Research Authors: Hamidreza Kazemeini Asghar Azizian Katayoun Ahmadi Source Type: research

Effects of Mesalamine Combined with Live Combined Bifidobacterium, Lactobacillus and Enterococcus Capsules on Intestinal Mucosa Barrier Function and Intestinal Microbiota in Mildly Active Crohn's Disease Patients
Conclusion: Mesalamine combined with Live combined Bifidobacterium, Lactobacillus and Enterococcus capsules are more effective in treating mildly active Crohn's disease.PMID:38159563 | DOI:10.1080/08941939.2023.2297565 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 30, 2023 Category: Surgery Authors: Meiqin Shen Yingqi Shi Zhenming Ge Junbo Qian Source Type: research

Lactobacillus acidophilus ‐Fermented Jujube Juice Ameliorates Chronic Liver Injury in Mice via Inhibiting Apoptosis and Improving the Intestinal Microecology
ConclusionsThis study suggests that FJJ exhibits a protective effect against CCl4-induced CLI mice by inhibiting apoptosis and oxidative stress, regulating liver lipid metabolism, and improving gut microecology. Jujube juice fermentation withL. acidophilus can be a food-grade supplement in treating CLI and related liver diseases. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 27, 2023 Category: Food Science Authors: Yu Zhang, Haitian Fang, Tong Wang, Zhigang Zhang, Tianxiang Zhu, Lei Xiong, Haiming Hu, Hongtao Liu Tags: Research Article Source Type: research

Characterization of Wnt signaling pathway under treatment of Lactobacillus acidophilus postbiotic in colorectal cancer using an integrated in silico and in vitro analysis
Sci Rep. 2023 Dec 27;13(1):22988. doi: 10.1038/s41598-023-50047-x.ABSTRACTColorectal cancer (CRC) is a prevalent and life-threatening cancer closely associated with the gut microbiota. Probiotics, as a vital microbiota group, interact with the host's colonic epithelia and immune cells by releasing a diverse range of metabolites named postbiotics. The present study examined the effects of postbiotics on CRC's prominent differentially expressed genes (DEGs) using in silico and in vitro analysis. Through single-cell RNA sequencing (scRNA-seq), we identified four DEGs in CRC, including secreted frizzled-related protein 1 (SFRP...
Source: Cancer Control - December 27, 2023 Category: Cancer & Oncology Authors: Nafiseh Erfanian Saeed Nasseri Adib Miraki Feriz Hossein Safarpour Mohammad Hassan Namaie Source Type: research

Novel Multi-Strain E3 Probiotic Formulation Improved Mental Health Symptoms and Sleep Quality in Hong Kong Chinese
Nutrients. 2023 Dec 8;15(24):5037. doi: 10.3390/nu15245037.ABSTRACTMental health issues have emerged as a significant concern in public health, given their association with physical and psychological comorbidities and the resultant socioeconomic burdens. Recent studies have highlighted the interplay between gut microbes and brain functions through the gut-brain axis. To investigate this further, we conducted a targeted 16S rRNA sequencing and comprehensive bioinformatic analysis among Southern Chinese individuals to explore the role of the gut microbiome in depression, anxiety, and sleep disturbance. We analyzed the differ...
Source: Genomics Proteomics ... - December 23, 2023 Category: Genetics & Stem Cells Authors: Helen Hoi Yin Chan Pui Ling Kella Siu Chi Tung Choy Un Kei Chan Junwei Zhou Chi Ho Wong Yuk Wai Lee Ho Wang Chan Joseph Chi Ching Tsui Steven King Fan Loo Stephen Kwok Wing Tsui Source Type: research

Novel Multi-Strain E3 Probiotic Formulation Improved Mental Health Symptoms and Sleep Quality in Hong Kong Chinese
Nutrients. 2023 Dec 8;15(24):5037. doi: 10.3390/nu15245037.ABSTRACTMental health issues have emerged as a significant concern in public health, given their association with physical and psychological comorbidities and the resultant socioeconomic burdens. Recent studies have highlighted the interplay between gut microbes and brain functions through the gut-brain axis. To investigate this further, we conducted a targeted 16S rRNA sequencing and comprehensive bioinformatic analysis among Southern Chinese individuals to explore the role of the gut microbiome in depression, anxiety, and sleep disturbance. We analyzed the differ...
Source: Genomics Proteomics ... - December 23, 2023 Category: Genetics & Stem Cells Authors: Helen Hoi Yin Chan Pui Ling Kella Siu Chi Tung Choy Un Kei Chan Junwei Zhou Chi Ho Wong Yuk Wai Lee Ho Wang Chan Joseph Chi Ching Tsui Steven King Fan Loo Stephen Kwok Wing Tsui Source Type: research