Development of an Antigen Delivery Platform Using Lactobacillus acidophilus Decorated With Heterologous Proteins: A Sheep in Wolf ’s Clothing Story
S-layers are bacterial structures present on the surface of several Gram-positive and Gram-negative bacteria that play a role in bacterial protection. In Lactobacillus acidophilus (L. acidophilus ATCC 4356), the S-layer is mainly composed of the protein SlpA. A tandem of two copies of the protein domain SLP-A (pfam: 03217) was identified at the C-terminal of SlpA, being this double SLP-A protein domain (in short dSLP-A) necessary and sufficient for the association of the protein to the L. acidophilus cell wall. A variety of proteins fused to the dSLP-A domain were able to spontaneously associate with high affinity to the c...
Source: Frontiers in Microbiology - October 27, 2020 Category: Microbiology Source Type: research

Neuroprotective effects of probiotics bacteria on animal model of Parkinson's disease induced by 6-hydroxydopamine: A behavioral, biochemical, and histological study.
Authors: Alipour Nosrani E, Tamtaji OR, Alibolandi Z, Sarkar P, Ghazanfari M, Azami Tameh A, Taghizadeh M, Banikazemi Z, Hadavi R, Naderi Taheri M Abstract Parkinson's disease (PD) is an age-associated, progressive, and common neurodegenerative disorder. It is characterized by dopaminergic neuron degeneration in the substantia nigra pars compacta. The involvement of oxidative stress, inflammation, and dysbiosis in PD has been confirmed and probiotics also have the ability to regulate the mentioned mechanisms. Here, we assessed probiotics supplementation effects on experimental model of PD. Thirty Male Wistar rats w...
Source: Journal of Immunoassay and Immunochemistry - October 22, 2020 Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research

Effect of Heat-Inactivated Compound Probiotics on Growth Performance, Plasma Biochemical Indices, and Cecal Microbiome in Yellow-Feathered Broilers
This study was carried out to investigate the effect of heat-inactivated compound probiotics on growth performance, plasma biochemical indices, and gut microbiota composition and functions in yellow-feathered broilers. A total of 360 1-day-old broilers were randomly divided into 3 groups, including a basal diet as negative control group (PC), basal diet plus antibiotics with 250 mg/kg calcium oxytetracycline and 200 mg/kg Nosiheptide as positive control (PC), and basal diet plus 500 mg/kg compound probiotics consisting of heat-inactivated Bacillus subtilis and Lactobacillus acidophilus BFI (BFI). Each group had 6 replicate...
Source: Frontiers in Microbiology - October 22, 2020 Category: Microbiology Source Type: research

Genes, Vol. 11, Pages 1234: Comparative Genomics of the Transport Proteins of Ten Lactobacillus Strains
ier The genus Lactobacillus includes species that may inhabit different anatomical locations in the human body, but the greatest percentage of its species are inhabitants of the gut. Lactobacilli are well known for their probiotic characteristics, although some species may become pathogenic and exert negative effects on human health. The transportome of an organism consists of the sum of the transport proteins encoded within its genome, and studies on the transportome help in the understanding of the various physiological processes taking place in the cell. In this communication we analyze the transport proteins and pr...
Source: Genes - October 21, 2020 Category: Genetics & Stem Cells Authors: Hassan Zafar Milton H. Saier Tags: Article Source Type: research

The effects of treatments with multistrain probiotics on serum aminotransferases, AST-ALT ratio, body weight and survivability scores of rats experimentally infected with Trypanosoma brucei
AbstractProbiotics can modulate gut-liver axis. Effects of administration of multistrain probiotics (MP) on liver damage and overall health of trypanosomic rats were investigated. Thirty male rats randomly assigned to five groups A –E (n = 6), and MP containingBifidobacterium BB-12,Lactobacillus delbrueckii LBY-27,Lactobacillus acidophilus LA-Z,Streptococcus thermophilus STY-31 andLactobacillus paracasei LC-01 were used for supplementation. From day 0 post-supplementation (PS), rats in groups A –C received 1 × 109, 5  × 109 and 10  × 109 ...
Source: Comparative Clinical Pathology - October 20, 2020 Category: Pathology Source Type: research

Lactobacillus acidophilus attenuates toxin production by Vibrio cholerae and shigella dysenteriae following intestinal epithelial cells infection
Publication date: December 2020Source: Microbial Pathogenesis, Volume 149Author(s): Shabnam Zeighamy Alamdary, Bita Bakhshi (Source: Microbial Pathogenesis)
Source: Microbial Pathogenesis - October 15, 2020 Category: Infectious Diseases Source Type: research

Rediscovering acidophilus milk, its quality characteristics, manufacturing methods, flavor chemistry and nutritional value
(Source: Critical Reviews in Food Science and Nutrition)
Source: Critical Reviews in Food Science and Nutrition - October 13, 2020 Category: Nutrition Authors: Farag, Mohamed A. El Hawary, Enas A. Elmassry, Moamen M. Source Type: research

Optimization of lead and cadmium biosorption by Lactobacillus acidophilus using response surface methodology
Publication date: Available online 10 October 2020Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Vahideh Afraz, Habibollah Younesi, Marzieh Bolandi, Mohammad Rasoul Hadiani (Source: Biocatalysis and Agricultural Biotechnology)
Source: Biocatalysis and Agricultural Biotechnology - October 12, 2020 Category: Biotechnology Source Type: research

Strategies to display heterologous proteins on the cell surface of lactic acid bacteria using as anchor the C-terminal domain of Lactobacillus acidophilus SlpA
This study presents the development of a protein delivery platform involvingL. acidophilus, a microorganism generally regarded as safe, which utilizes the contiguous, non-covalently attached S-layer at the cell surface of the bacterium without introducing any genetic modification.Graphic abstract (Source: World Journal of Microbiology and Biotechnology)
Source: World Journal of Microbiology and Biotechnology - October 12, 2020 Category: Microbiology Source Type: research

Molecules, Vol. 25, Pages 4638: Different Ultrasound Exposure Times Influence the Physicochemical and Microbial Quality Properties in Probiotic Goat Milk Yogurt
a Carlos Conte-Junior Despite goat milk having health benefits over cow milk, goat milk yogurt (GY) presents low consistency and viscosity, which reduces its overall acceptability by the consumer. Thus, new innovative methods can be an alternative to improve the quality of GY. Hence, this study aimed to investigate the effect of ultrasound (US) treatment with different sonication times on quality parameters of probiotic GY during refrigerated storage. US treatment was conducted at 20 KHz for 3, 6, and 9 min in yogurt. Lactobacillus bulgaricus and Lactobacillus acidophilus LA-5 were sensitive to US treatment, presenti...
Source: Molecules - October 12, 2020 Category: Chemistry Authors: Karina Delgado Carla Vieira Ilyes Dammak Beatriz Fras ão Ana Br ígida Marion Costa Carlos Conte-Junior Tags: Article Source Type: research

Novel bioactive caries-detecting dye solution: Cytotoxicity, antimicrobial activity, scanning electron microscope, and stereomicroscopic analysis in diagnosis of dental caries
Conclusions: Profound synergistic effect for BCD was observed with advantage of radiographic assessment. (Source: Journal of Conservative Dentistry)
Source: Journal of Conservative Dentistry - October 10, 2020 Category: Dentistry Authors: Govind Shashirekha Amit Jena Neeta Mohanty Sushanta Kumar Kamilla Source Type: research

Lactobacillus acidophilus Antimicrobial Peptide Is Antagonistic to Aeromonas hydrophila
We identified an antimicrobial peptide (AMP) from Lactobacillus acidophilus that was antagonistic to Aeromonas hydrophila. In vitro studies such as well-diffusion and field trials revealed that the AMP was active against A. hydrophila. The field trials of AMP using A. hydrophila-infected Channa striatus with a mannone oligosaccharide (MOS) prebiotic, A. hydrophila antigens, A. hydrophila-infected fish serum, L. acidophilus, and Lactobacillus cell free-supernatant (LABS-CFS) on an indicator organism further revealed that the antimicrobial agent could protect C. striatus. Other than the AMP, none of the above were able to el...
Source: Frontiers in Microbiology - October 9, 2020 Category: Microbiology Source Type: research

Protective efficacy of probiotics on the treatment of acute rotavirus diarrhea in children: an updated meta-analysis.
CONCLUSIONS: Probiotics could reduce the occurrence of acute RVD in children, especially in Caucasian population. Our findings still needed to be further validated in a multi-center institution with larger sample size and more qualified data. PMID: 33015812 [PubMed - in process] (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 7, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Assessment of oncogenic role of intestinal microbiota in colorectal cancer patients
AbstractIntroductionThe direct association between some microbial species and cancers, such as in colorectal cancer (CRC), has been disclosed.ObjectiveThe aim of this study was to evaluate the changes in intestinal microbiota in subjects with CRC compared with healthy group.MethodsThree-hundred fecal specimens were gathered from patients with CRC and 300 from healthy individuals during March 2014 to October 2019 from two hospitals in Tehran. The informed consent form and the questionnaire were completed by the patients. Following the identification ofLactobaccilus acidophilus (L. acidophilus),Lactobacillus palntarom (L. pa...
Source: Journal of Gastrointestinal Cancer - October 2, 2020 Category: Cancer & Oncology Source Type: research

IJERPH, Vol. 17, Pages 7239: Addition of Probiotics to Anti-Obesity Therapy by Percutaneous Electrical Stimulation of Dermatome T6. A Pilot Study
Alonso Jaime Ruiz-Tovar Obesity is becoming a pandemic and percutaneous electrical stimulation (PENS) of dermatome T6 has been demonstrated to reduce stomach motility and appetite, allowing greater weight loss than isolated hypocaloric diets. However, modulation of intestinal microbiota could improve this effect and control cardiovascular risk factors. Our objective was to test whether addition of probiotics could improve weight loss and cardiovascular risk factors in obese subjects after PENS and a hypocaloric diet. A pilot prospective study was performed in patients (n = 20) with a body mass index (BMI) &gt...
Source: International Journal of Environmental Research and Public Health - October 2, 2020 Category: Environmental Health Authors: Oscar Lorenzo Marta Crespo-Yanguas Tianyu Hang Jairo Lumpuy-Castillo Artur M. Hern ández Carolina Llavero MLuisa Garc ía-Alonso Jaime Ruiz-Tovar Tags: Article Source Type: research

Participation of the intestinal microbiota in the mechanism of beneficial effect of treatment with synbiotic Syngut on experimental colitis under stress conditions.
This study was designed to determine the effect of daily treatment with synbiotic (Syngut) containing inulin, Lactobacillus acidophilus, Bifidobacterium lactis W51, Lactobacillus plantarum W21 and Lactococcus lactis applied i.g. at a dose of 50 mg/kg i.g. on the colonic damage and colonic mucosal blood flow in rats with experimentally induced TNBS-colitis that were additionally exposed or not to acute stress (episodes of cold restraint stress every other day before colitis induction). Control rats received daily treatment with vehicle (saline, i.g.) or mesalazine (50 mg/kg-d i.g.), the standard drug recommended in therapy ...
Source: Journal of Physiology and Pharmacology - October 1, 2020 Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research

Effect of Aerva sanguinolenta (Lal bishalyakarani) plant extract on biofilm-induced human enamel demineralization: An in vitro study
Conclusion: Enamel exposed to 2 ml of 0.2% solution of A. sanguinolenta for 2 min could fairly inhibit formation of biofilm and positively inhibit underlying demineralization in cariogenic environment. (Source: Journal of Indian Society of Pedodontics and Preventive Dentistry)
Source: Journal of Indian Society of Pedodontics and Preventive Dentistry - September 28, 2020 Category: Dentistry Authors: Shabnam Zahir Tamal Kanti Pal Abhijit Sengupta Shibendu Biswas Shyamal Bar Source Type: research

Probiotics alter biofilm formation and the transcription of Porphyromonas gingivalis virulence-associated genes.
Conclusions: Probiotics affect P. gingivalis biofilm formation by down-regulating overall PgVAFs with the most pronounced effect observed for L. acidophilus LA5. PMID: 32944156 [PubMed] (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - September 20, 2020 Category: Microbiology Tags: J Oral Microbiol Source Type: research

Protective effects of Lactobacillus acidophilus NX2-6 against oleic acid-induced steatosis, mitochondrial dysfunction, endoplasmic reticulum stress and inflammatory responses
Publication date: November 2020Source: Journal of Functional Foods, Volume 74Author(s): Chao Tang, Fanqiang Meng, Xinyi Pang, Meirong Chen, Libang Zhou, Zhaoxin Lu, Yingjian Lu (Source: Journal of Functional Foods)
Source: Journal of Functional Foods - September 19, 2020 Category: Nutrition Source Type: research

Antifungal effects of Lactobacillus acidophilus and Lactobacillus plantarum against different oral Candida species isolated from HIV/ AIDS patients: an in vitro study.
In this study, the antifungal effects of both cells and cell-free supernatants (CFSs) of L. acidophilus and L. plantarum were investigated against different oral Candida species by co-aggregation, agar overlay interference and broth microdilution assays, respectively. Our results showed that the highest co-aggregation ratio of the two tested Lactic acid bacteria (LAB) was observed for C. krusei. Both L. acidophilus and L. plantarum at cell concentrations 1010 to 102 cfu/ml were able to inhibit the growth of most of the oral Candida species, except for C. albicans, and to some C. krusei. In this study, MIC and MFC values fo...
Source: Journal of Oral Microbiology - September 16, 2020 Category: Microbiology Tags: J Oral Microbiol Source Type: research

Lactobacillus acidophilus and Bifidobacterium longum exhibit antiproliferation, anti-angiogenesis of gastric and bladder cancer: Impact of COX2 inhibition
Publication date: Available online 6 September 2020Source: PharmaNutritionAuthor(s): Hanady G. Nada, Thangirala Sudha, Noureldien H.E. Darwish, Shaker A. Mousa (Source: PharmaNutrition)
Source: PharmaNutrition - September 6, 2020 Category: Nutrition Source Type: research

Effectiveness of a Direct-Fed Microbial Product Containing Lactobacillus acidophilus and Lactobacillus casei in Reducing Fecal Shedding of Escherichia coli O157:H7 in Commercial Feedlot Cattle
Foodborne Pathogens and Disease, Ahead of Print. (Source: Foodborne Pathogens and Disease)
Source: Foodborne Pathogens and Disease - September 6, 2020 Category: Food Science Authors: Diana M.A. Dewsbury Natalia Cernicchiaro Brandon Depenbusch T.G. Nagaraja David G. Renter Source Type: research

Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium.
Abstract Microbial processes are being developed to transform flavonoid glycosides to varieties of metabolites with higher bioavailability. The aim of this study was to determine the metabolic activity and survival of five lactic acid bacteria (LAB) stains (L. rhamnosus LRa05, L. casei LC89, L. plantarum N13, L. acidophilus LA85, and L. brevis LB01) in two different citrus flavanone standards (hesperetin-7-O-rutinoside and naringenin-7-O-rutinoside). The enzymatic activity, metabolites, antioxidant activities, and α-glucosidase inhibition property in the two standards were also investigated before and after ...
Source: Bioprocess and Biosystems Engineering - September 3, 2020 Category: Biomedical Engineering Authors: Guo X, Guo A, Li E Tags: Bioprocess Biosyst Eng Source Type: research

A class Ⅲ bacteriocin with broad-spectrum antibacterial activity from Lactobacillus acidophilus NX2-6 and its preservation in milk and cheese
Publication date: Available online 2 September 2020Source: Food ControlAuthor(s): Fanqiang Meng, Xiaoyu Zhu, Haizhen Zhao, Ting Nie, Fengxia Lu, Zhaoxin Lu, Yingjian Lu (Source: Food Control)
Source: Food Control - September 3, 2020 Category: Food Science Source Type: research

Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics
Type 1 autoimmune diabetes is an autoimmune disease characterized by specific destruction of pancreatic β-cells producing insulin. Recent studies have shown that gut microbiota and immunity are closely linked to systemic immunity, affecting the balance between pro-inflammatory and regulatory immune responses. Altered gut microbiota may be causally related to the development of immune-mediated diseases, and probiotics have been suggested to have modulatory effects on inflammatory diseases and immune disorders. We studied whether a probiotic combination that has immunomodulatory effects on several inflammatory diseases ...
Source: Frontiers in Immunology - September 2, 2020 Category: Allergy & Immunology Source Type: research

Effect of the apple cultivar on cloudy apple juice fermented by a mixture of Lactobacillus acidophilus, Lactobacillus plantarum, and Lactobacillus fermentum
Publication date: Available online 28 August 2020Source: Food ChemistryAuthor(s): Wanying Peng, Diaoqin Meng, Tianli Yue, Zhouli Wang, Zhenpeng Gao (Source: Food Chemistry)
Source: Food Chemistry - August 29, 2020 Category: Food Science Source Type: research

The effects of curcumin and Lactobacillus acidophilus on certain hormones and insulin resistance in rats with metabolic syndrome
In this study, we tried to investigate the effects of curcumin andLactobacillus acidophilus probiotics, given individually and in combination, to insulin, adipokines and nitric oxide changes and insulin resistance as experimental treatment of metabolic syndrome.MethodsFive groups were formed in the study. Fructose (20%) was administered with drinking water for 8 weeks to develop metabolic syndrome. For treatment, curcumin (100 mg/kg/day) andL. acidophilus (2  × 108 cfu/ml/day) were given individually or in combination for the last four weeks. At the end of the experiment; insulin, resistin, leptin, adip...
Source: Journal of Diabetes and Metabolic Disorders - August 26, 2020 Category: Endocrinology Source Type: research

Bacterial Cellulose Nano Fiber (BCNF) as carrier support for the immobilization of probiotic, Lactobacillus acidophilus 016
Publication date: Available online 20 August 2020Source: Carbohydrate PolymersAuthor(s): Jayani Tilak, B. Sanjeev, S. Marimuthu, Sivakumar Uthandi (Source: Carbohydrate Polymers)
Source: Carbohydrate Polymers - August 22, 2020 Category: Biomedical Science Source Type: research

Microencapsulation of Probiotic Strains by Lyophilization Is Efficient in Maintaining the Viability of Microorganisms and Modulation of Fecal Microbiota in Cats.
This study aimed to (i) evaluate the effects of two types of microencapsulation techniques, different encapsulating agents, and 120 days of storage on the viability of a commercial probiotic product and (ii) investigate fecal microbiota populations and fecal characteristics of adult cats fed with diets supplemented with probiotics. Three experimental treatments were evaluated: T1, commercial feed (control); T2, commercial kibbles coated with probiotics; and T3, commercial feed supplemented with freeze-dried probiotics and fructooligosaccharides. Fructooligosaccharides and gum arabic were used as encapsulating agents for fr...
Source: International Journal of Microbiology - August 19, 2020 Category: Microbiology Tags: Int J Microbiol Source Type: research

Irradiation-Induced Intestinal Damage Is Recovered by the Indigenous Gut Bacteria Lactobacillus acidophilus
This study provides the first evidence that the indigenous gut bacteria L. acidophilus enhance intestinal epithelial function with respect to irradiation-induced intestinal damage by improving intestinal stem cell function and cell differentiation. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - August 17, 2020 Category: Microbiology Source Type: research

Recombinant Lactobacillus acidophilus expressing S1 and S2 domains of porcine epidemic diarrhea virus could improve the humoral and mucosal immune levels in mice and sows inoculated orally
Publication date: Available online 16 August 2020Source: Veterinary MicrobiologyAuthor(s): Yue Zang, Ye Tian, Yungang Li, Ruixue Xue, Liping Hu, Dong Zhang, Shengfu Sun, Guisheng Wang, Jing Chen, Zouran Lan, Shaoli Lin, Shijin Jiang (Source: Veterinary Microbiology)
Source: Veterinary Microbiology - August 17, 2020 Category: Veterinary Research Source Type: research

Does probiotic supplementation aid weight loss? A randomized, single-blind, placebo-controlled study with Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 supplementation.
CONCLUSION: The results of this investigation do not support claims made by probiotic products manufacturers, that they aid weight loss. Our results seem to support an argument that weight loss is mostly associated with food habits and dietary behaviors, not probiotic intake. It is possible that probiotic supplementation may play a facilitating weight loss but has no effect without dietary intervention. Another possible explanation is that due to strain specificity-bacteria strains used in this study are not effective for weight loss. LEVEL OF EVIDENCE: I: randomized controlled trial. PMID: 32797375 [PubMed - as ...
Source: Eating and weight disorders : EWD - August 13, 2020 Category: Eating Disorders & Weight Management Authors: Czajeczny D, Kabzińska K, Wójciak RW Tags: Eat Weight Disord Source Type: research

S-layer associated proteins contribute to the adhesive and immunomodulatory properties of Lactobacillus acidophilus NCFM
Surface layers (S-layers) are two-dimensional crystalline arrays of repeating proteinaceous subunits that form the outermost layer of many bacterial cell envelopes. Within the Lactobacillus genus, S-layer presenc... (Source: BMC Microbiology)
Source: BMC Microbiology - August 12, 2020 Category: Microbiology Authors: Courtney Klotz, Yong Jun Goh, Sarah O ’Flaherty and Rodolphe Barrangou Tags: Research article Source Type: research

Effect of a Dual-Strain Probiotic on Necrotizing Enterocolitis in Neonates with Ductal-Dependent Congenital Heart Disease: A Retrospective Cohort Study
Conclusions: This is the first study to investigate the effect of a dual-strain probiotic on NEC in CHD patients. Infants with aortic arch malformations appear to benefit from dual-strain probiotics. Due to the scarcity of concurrence of ductal-dependent CHD and NEC, a clinical trial on probiotics to decrease risk of NEC in infants with ductal-dependent CHD would require several thousand infants.Neonatology (Source: Neonatology)
Source: Neonatology - August 11, 2020 Category: Perinatology & Neonatology Source Type: research

Effect of a Dual-Strain Probiotic on Necrotizing Enterocolitis in Neonates with Ductal-Dependent Congenital Heart Disease: A Retrospective Cohort Study.
CONCLUSIONS: This is the first study to investigate the effect of a dual-strain probiotic on NEC in CHD patients. Infants with aortic arch malformations appear to benefit from dual-strain probiotics. Due to the scarcity of concurrence of ductal-dependent CHD and NEC, a clinical trial on probiotics to decrease risk of NEC in infants with ductal-dependent CHD would require several thousand infants. PMID: 32781449 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 10, 2020 Category: Perinatology & Neonatology Authors: Kocjancic L, Bührer C, Berger F, Boos V Tags: Neonatology Source Type: research

In situ production of conjugated linoleic acid by Bifidobacterium lactis BB12 and Lactobacillus acidophilus LA5 in milk model medium
Publication date: October 2020Source: LWT, Volume 132Author(s): Saber Amiri, Reza Rezaei Mokarram, Mahmoud Sowti Khiabani, Mahmoud Rezazadeh Bari, Mohammad Alizadeh Khaledabad (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - August 1, 2020 Category: Food Science Source Type: research

Thermosonication as an alternative method for processing, extending the shelf life, and conserving the quality of pulque: A non-dairy Mexican fermented beverage.
, Miranda-Castilleja DE Abstract The aim of this study was to evaluate thermosonication as an alternative method for the pasteurization of pulque in order to improve its shelf life and retain its quality parameters. Thermosonication was carried out at 50 °C using amplitudes of 75% (for 6 and for 9 min), 85% (for 4 and for 6 min), and 95% (for 3 and for 5 min). These were the optimal conditions found for processing pulque by thermosonication. Physicochemical (acidity, color, alcohol content, and sensory analysis) and microbiological (lactic acid bacteria and yeasts) parameters were determine...
Source: Ultrasonics Sonochemistry - July 29, 2020 Category: Chemistry Authors: Alcántara-Zavala AE, Figueroa-Cárdenas JD, Pérez-Robles JF, Arámbula-Villa G, Miranda-Castilleja DE Tags: Ultrason Sonochem Source Type: research

The effect of iron oxide nanoparticles on Lactobacillus acidophilus growth at pH 4.
Abstract Probiotics, in particular, lactic acid bacteria (LAB) are widely used as starter cultures in food and pharmaceutical industries. Presence of LAB supports the production and preservation of a diverse range of food products, provides a positive effect on the human gastrointestinal tract, and prevents the progression of many diseases. However, the main limiting factor in the application of LAB is that they hardly survive in acidic conditions, including the human digestive system. This factor inhibits LAB to maintain their functionality and deliver their health benefits to the host. For this purpose, magnetic...
Source: Bioprocess and Biosystems Engineering - July 29, 2020 Category: Biomedical Engineering Authors: Novin D, Seifan M, Ebrahiminezhad A, Berenjian A Tags: Bioprocess Biosyst Eng Source Type: research

Immune enhancing effects of Lactobacillus acidophilus on Newcastle disease vaccination in chickens
Publication date: Available online 18 July 2020Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Sahar Nouri Gharajalar, Parisa Mirzai, Katayoon Nofouzi, Mohammad Sadegh Madadi (Source: Comparative Immunology, Microbiology and Infectious Diseases)
Source: Comparative Immunology, Microbiology and Infectious Diseases - July 18, 2020 Category: Infectious Diseases Source Type: research

Immune enhancing effects of Lactobacillus acidophilus on Newcastle disease vaccination in chickens.
CONCLUSION: In conclusion, L. acidophilus can use for improving immunogenicity of NDV vaccination programs. PMID: 32721773 [PubMed - as supplied by publisher] (Source: Comparative immunology, microbiology and infectious diseases.)
Source: Comparative immunology, microbiology and infectious diseases. - July 17, 2020 Category: Allergy & Immunology Authors: Nouri Gharajalar S, Mirzai P, Nofouzi K, Madadi MS Tags: Comp Immunol Microbiol Infect Dis Source Type: research

Pilot Study of Probiotic Supplementation on Uremic Toxicity and Inflammatory Cytokines in Chronic Kidney Patients
Conclusion: Lactobacillus acidophilus strains given as probiotic were not able to reduce serum levels of uremic toxins and biomarkers of inflammation in CKD patients in stage 3 and 4. (Source: Current Nutrition and Food Science)
Source: Current Nutrition and Food Science - July 14, 2020 Category: Nutrition Source Type: research

Protective effect of probiotic Lactobacillus acidophilus against the toxicity of beauvericin mycotoxin on the Caco-2  cell line.
Protective effect of probiotic Lactobacillus acidophilus against the toxicity of beauvericin mycotoxin on the Caco-2 cell line. Toxicon. 2020 Jul 13;: Authors: Mohseni M, Salim A, Nadri S, Hosseini MJ, Rokni-Zadeh H Abstract The present study evaluated the protective effect of Lactobacillus acidophilus against the toxicity of the Beauvericin on the Caco-2 cell line. After culturing Caco-2 cells and applying different concentrations of Beauvericin and L. acidophilus individually and in combination, cell viability was assessed by enzyme-linked immunosorbent assay at different times. The results in...
Source: Toxicon - July 12, 2020 Category: Toxicology Authors: Mohseni M, Salim A, Nadri S, Hosseini MJ, Rokni-Zadeh H Tags: Toxicon Source Type: research

Oral Intake of Lactobacilli Can Be Helpful in Symptomatic Bacterial Vaginosis: A Randomized Clinical Study
Conclusions Oral intake of L. crispatus LMG S-29995, L. brevis, and L. acidophilus can significantly decrease percent of recurrences of BV in recently treated women and prolong time to recurrence of the disease. (Source: Journal of Lower Genital Tract Disease)
Source: Journal of Lower Genital Tract Disease - June 23, 2020 Category: OBGYN Tags: Vaginal Source Type: research

Human probiotic bacteria attenuate Pseudomonas aeruginosa biofilm and virulence by quorum-sensing inhibition.
This study suggests that the metabolites of L. casei and L. acidophilus could be a promising alternative to combat the pathogenicity of P. aeruginosa. PMID: 32573275 [PubMed - as supplied by publisher] (Source: Biofouling)
Source: Biofouling - June 22, 2020 Category: Molecular Biology Authors: Díaz MA, González SN, Alberto MR, Arena ME Tags: Biofouling Source Type: research

Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives.
The objective of this communication is to present and analyze the recent results from the LAPIBSS study in order to improve future clinical trials on the effects of Lactobacillus strains in the treatment of irritable bowel syndrome (IBS). Using a tightly-controlled clinical trial protocol with the highest Jadad score of 5/5, the current trial aimed to demonstrate the efficacy of a 2-strain mixture of Lactobacillus acidophilus (L. acidophilus) to improve IBS symptoms. Eighty patients diagnosed with IBS according to Rome III criteria were recruited to a multicentric, double-blind, in parallel groups, placebo-controlled, rand...
Source: Cellular and Molecular Biology - June 18, 2020 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

The antibacterial effect of caffeic acid phenethyl ester on cariogenic bacteria and Streptococcus mutans biofilms.
In conclusion, CAPE appears to be a new agent with anticariogenic potential, not only via inhibition of the growth of cariogenic bacteria. PMID: 32540977 [PubMed - as supplied by publisher] (Source: Antimicrobial Agents and Chemotherapy)
Source: Antimicrobial Agents and Chemotherapy - June 14, 2020 Category: Microbiology Authors: Niu Y, Wang K, Zheng S, Wang Y, Ren Q, Li H, Ding L, Li W, Zhang L Tags: Antimicrob Agents Chemother Source Type: research

Thermostable arginase from Sulfobacillus acidophilus with neutral pH optimum applied for high-efficiency L-ornithine production.
This study aims to use neutral pH optimum arginase as the catalyst for high-efficiency L-ornithine production. Sulfobacillus acidophilus arginase was firstly cloned and overexpressed in Escherichia coli. The purified enzyme was obtained, and the molecular mass determination showed that this arginase was a hexamer. S. acidophilus arginase possessed similarities with the other arginases such as the conserved sequences, purification behavior, and the necessity for Mn2+ as a cofactor. The maximum enzyme activity was obtained at pH 7.5 and 70 °C. Thermostability and pH stability analysis showed that the arginase w...
Source: Applied Microbiology and Biotechnology - June 10, 2020 Category: Microbiology Authors: Huang K, Zhang S, Guan X, Liu J, Li S, Song H Tags: Appl Microbiol Biotechnol Source Type: research

Effects of Different Sample Pulverisation Methods on the Extraction of Metabolites from the Fermented Cottonseed Meal Based on UPLC-Q-TOF-MS.
This study built a foundation work for the further research of the fermented feed metabolomics. PMID: 32524273 [PubMed - as supplied by publisher] (Source: Current Microbiology)
Source: Current Microbiology - June 9, 2020 Category: Microbiology Authors: Wang Y, Xie H, Liu D, Wang Y, Liu C, Khan MA, Jiang J, Zhang W Tags: Curr Microbiol Source Type: research

Characterization of the sortase A from Lactobacillus acidophilus ATCC 4356 involved in adherence to intestinal cells
Future Microbiology, Ahead of Print. (Source: Future Microbiology)
Source: Future Microbiology - May 31, 2020 Category: Microbiology Authors: Zhen Wu Jing Wu Fengxuan Lang Zhendong Cai Xiaoqun Zeng Yuxing Guo Xiaotao Liu Daodong Pan Source Type: research