Integrative Approaches to Managing Gut Health
AbstractPurpose of ReviewTo summarize key integrative approaches to managing common gastrointestinal conditions.Recent FindingsLifestyle interventions like diet, exercise, and stress reduction impact the gut microbiome and gastrointestinal symptoms. Evidence supports mind-body therapies, herbs, certain supplements, and other modalities as complimentary approaches, when appropriate, for common conditions like irritable bowel syndrome or gastroesophageal reflux disease.SummaryAn integrative approach optimizes both conventional treatments and incorporates lifestyle modifications, complimentary modalities, and the doctor-patie...
Source: Current Gastroenterology Reports - March 12, 2024 Category: Gastroenterology Source Type: research
Comment on: “Effectiveness of sleeve gastrectomy plus fundoplication versus sleeve gastrectomy alone for treatment of patients with severe obesity: a systematic review and meta-analysis”
Laparoscopic sleeve gastrectomy (LSG) is generally associated with superior perioperative safety profile when compared to laparoscopic Roux-en-Y gastric bypass (LRYGB); however, LRYGB offers better gastroesophageal reflux disease (GERD) control (1). In fact, LRYGB is considered the technique of choice for patients with GERD (2). Additionally, for patients without GERD, there is an increased risk of de novo GERD with LSG as opposed to LRYGB. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - March 11, 2024 Category: Surgery Authors: Guilherme S. Mazzini, Guilherme M. Campos Tags: Editorial Source Type: research
Cumulative Anticholinergic Burden and its Predictors among Older Adults with Alzheimer ’s Disease Initiating Cholinesterase Inhibitors
ConclusionFour out of five older adults with AD had some level of anticholinergic burden, with over 60% having moderate –high anticholinergic burden. Several predisposing, enabling, and need factors were associated with the cumulative anticholinergic burden. The study findings suggest a critical need to minimize the cumulative anticholinergic burden to improve AD care. (Source: Drugs and Aging)
Source: Drugs and Aging - March 11, 2024 Category: Geriatrics Source Type: research
Prolonged acid reflux monitoring using acid exposure time and DeMeester score: two days are not enough
ConclusionsIn patients undergoing extended pH monitoring, almost half were found to have an abnormal pH study after a normal study on Day 1. An additional 25% of patients had a change in study interpretation by extending the study beyond 48 h. Our findings suggest only 48 h of pH monitoring will miss a diagnosis of GERD in a clinically important number of patients. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - March 11, 2024 Category: Surgery Source Type: research
Comment on: Effectiveness of sleeve gastrectomy plus fundoplication versus sleeve gastrectomy alone for treatment of patients with severe obesity: a systematic review and meta-analysis
Laparoscopic sleeve gastrectomy (LSG) is generally associated with a superior perioperative safety profile when compared with laparoscopic Roux-en-Y gastric bypass (LRYGB); however, LRYGB offers better gastroesophageal reflux disease (GERD) control [1]. In fact, LRYGB is considered the technique of choice for patients with GERD [2]. Additionally, for patients without GERD, there is an increased risk of de novo GERD with LSG as opposed to LRYGB. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - March 11, 2024 Category: Surgery Authors: Guilherme S. Mazzini, Guilherme M. Campos Tags: Editorial comment Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
Gastrointestinal dysfunction in the valproic acid induced model of social deficit in rats
Auton Neurosci. 2024 Feb 29;253:103161. doi: 10.1016/j.autneu.2024.103161. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) has increased in incidence over the past several decades, and is associated with a range of co-morbidities including gastrointestinal (GI) dysfunctions including gastroesophageal reflux, abdominal pain, bloating, constipation and/or diarrhea. Several animal models have been used that replicate several aspects of ASD but no single model has been able to replicate the entire disease pathophysiology. In humans, prenatal exposure to valproic acid (VPA) has been identified as a significant risk...
Source: Autonomic Neuroscience - March 10, 2024 Category: Neuroscience Authors: Ashley N Varley Kirsteen N Browning Source Type: research
