Use of isotretinoin among girls and women of childbearing age and occurrence of isotretinoin-exposed pregnancies in Germany: A population-based study
ConclusionsIsotretinoin use among girls and women of childbearing age increased in Germany between 2004 and 2019, and there was a considerable number of pregnancies likely exposed to isotretinoin in a critical period. This highlights the importance of monitoring compliance with the existing risk minimization measures for isotretinoin in Germany. (Source: PLoS Medicine)
Source: PLoS Medicine - January 25, 2024 Category: Internal Medicine Authors: Jonas Reinold Source Type: research
Isotretinoin-Induced Dyslipidemia: a Single-Center Study in Saudi Arabia
(Source: Patient Preference and Adherence)
Source: Patient Preference and Adherence - January 19, 2024 Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
Network Analysis Finds Oral Isotretinoin Most Effective for Acne Vulgaris
Am Fam Physician. 2024 Jan;109(1):Online.NO ABSTRACTPMID:38227885 (Source: American Family Physician)
Source: American Family Physician - January 16, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research
Network Analysis Finds Oral Isotretinoin Most Effective for Acne Vulgaris
Am Fam Physician. 2024 Jan;109(1):Online.NO ABSTRACTPMID:38227885 (Source: American Family Physician)
Source: American Family Physician - January 16, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research
Practice and attitude of general practitioners towards initiating isotretinoin for acne vulgaris in Fars province, Iran: cross-sectional study
Since general practitioners manage acne-related referrals, there needs to be more information in Iran about how drugs such as Isotretinoin are prescribed and the treatment plan. Thus, this study aimed to evalu... (Source: BMC Family Practice)
Source: BMC Family Practice - January 13, 2024 Category: Primary Care Authors: Parisa Hosseinpour, Ghazal Gholamabbas, Fatemehsadat Pezeshkian, Amirhossein Erfani, Reza Shahriarirad and Ahmad Reza Parhizkar Tags: Research Source Type: research
Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects
Biol Trace Elem Res. 2024 Jan 10. doi: 10.1007/s12011-023-04053-9. Online ahead of print.ABSTRACTIsotretinoin is an effective treatment against acne vulgaris, but it also causes many side effects during and after the treatment. The relationship between the changes in the levels of plasma trace elements of patients with AV after 3 months of isotretinoin treatment and the side effects was investigated in the study. Plasma samples of 35 patients were collected before and after isotretinoin treatment. Samples were analyzed by Inductively Coupled Plasma-Mass Spectrometer. After treatment, the levels of phosphorus, magnesium, an...
Source: Biological Trace Element Research - January 10, 2024 Category: Biology Authors: Tugrul Cagri Akman Mustafa Yazici Alptug Atila Cuma Mertoglu Source Type: research
A novel predictive method for risk stratification in acne patients receiving isotretinoin: an analysis of laboratory abnormalities and changes in inflammatory parameters
CONCLUSIONS: We found that a baseline cholesterol level of 163.9 mg/dl and a baseline triglycerides level of 85.5 mg/dL are highly specific and sensitive in detecting grade 1 abnormalities at the one-month follow-up. This novel prediction approach serves as an effective risk stratification method for isotretinoin acne patients.PMID:38186323 | DOI:10.1080/09546634.2023.2301435 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 8, 2024 Category: Dermatology Authors: Rand Murshidi Salsabiela Bani Hamad Assem Al Refaei Nour Shewaikani Moayad Shaf'ei Sara N Alshoubaki Tala A Haddad Tawfiq Khasawneh Taima Fkheideh Mahmoud Abdallat Source Type: research
The Microbiome and Acne: Perspectives for Treatment
AbstractThe skin microbiome consists of the microorganisms populating the human skin.Cutibacterium acnes (C. acnes, formerly namedPropionibacterium acnes) is recognized as a key factor in acne development, regulating inflammatory and immune pathways. Dysbiosis has been described as the imbalance in skin microbiome homeostasis and may play a role in acne pathogenesis. Microbial interference has been shown to be a contributor to healthy skin homeostasis and staphylococcal strains may exclude acne-associatedC. acnes phylotypes. In this review we present an update on the skin microbiome in acne and discuss how current acne...
Source: Dermatology and Therapy - January 6, 2024 Category: Dermatology Source Type: research
The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris
Conclusion:Supplementation of ω-3 fatty acids could alleviate the inflammation of acne vulgaris by increasing the abundance of butyric acid producing bacteria.PMID:38164791 | DOI:10.1080/09546634.2023.2299107 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 2, 2024 Category: Dermatology Authors: Yaxin Huang Fuming Liu Jindong Lai Shiyu Jiang Xiaoqi Tan Lingna Chen Yong Xu Xia Xiong Yongqiong Deng Source Type: research
Errors in Figures 3 and 4
This article has been corrected. (Source: JAMA Dermatology)
Source: JAMA Dermatology - January 1, 2024 Category: Dermatology Source Type: research
Pityriasis Rubra Pilaris: An Updated Review of Clinical Presentation, Etiopathogenesis, and Treatment Options
AbstractPityriasis rubra pilaris (PRP) is a rare papulosquamous reaction pattern with a significant impact on quality of life. Type I PRP is the most common PRP variant, presenting as erythematous papules emerging in a follicular distribution and later coalescing into plaques with characteristic islands of sparing; histologically, an alternating pattern of orthokeratosis and parakeratosis is considered the hallmark of PRP (checkerboard hyperkeratosis). Other PRP variants (types II –V) differ in their age of onset and clinical presentation. Type VI PRP is a rare PRP subtype associated with human immunodeficiency virus inf...
Source: American Journal of Clinical Dermatology - December 30, 2023 Category: Dermatology Source Type: research
The primary role of sebum in the pathophysiology of acne vulgaris and its therapeutic relevance in acne management
CONCLUSIONS: To date, only combined oral contraceptives and oral spironolactone (both limited to female patients), oral isotretinoin and topical clascoterone (cortexolone 17α-propionate) modulate sebum production in patients with AV. A better understanding of mechanisms underlying sebaceous gland changes driving AV development is needed to expand the AV treatment armamentarium.PMID:38146664 | DOI:10.1080/09546634.2023.2296855 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: James Q Del Rosso Leon Kircik Source Type: research
