Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Assessment of the In Vivo Reprotoxicity of Isotretinoin in Sprague-Dawley Male Rat
CONCLUSION: These observations suggest that ISO was reprotoxic, and future therapies should be further reassessed.PMID:37587808 | DOI:10.2174/1570163820666230816155855 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - August 17, 2023 Category: Drugs & Pharmacology Authors: Ahmad Khalil Mai Daradkeh Amneh Alrabie Hasan Abo Siam Source Type: research

Impact of the 2018 revised Pregnancy Prevention Programme by the European Medicines Agency on the use of oral retinoids in females of childbearing age in Denmark, Italy, Netherlands, and Spain: an interrupted time series analysis
Conclusion: This study shows a limited impact of the 2018 RMMs on oral retinoids utilisation patterns among females of child-bearing age in four European countries. Pregnancies still occur during retinoid use, and oral retinoids are still prescribed to pregnant women. Contraception and pregnancy testing information was limited in most databases. Regulators, policymakers, prescribers, and researchers must rethink implementation strategies to avoid any pregnancy becoming temporarily related to retinoid use. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2023 Category: Drugs & Pharmacology Source Type: research